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Pathology Pt. 5 > Buzzwords > Flashcards

Buzzwords Flashcards

1
Q

Brushfield spots in the iris

A

Down syndrome

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2
Q

Single palmar crease

A

Down syndrome

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3
Q

Barr body

A

Klinefelter

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4
Q

Gynecomastia

A

Klinefelter

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5
Q

Silver-white scaly lesion

A

Psoriasis

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6
Q

Neutrophils in the stratum corneum

A

Psoriasis

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7
Q

multiple minute bleeding points

A

Psoriasis

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8
Q

edema between keratinocytes

A

eczema

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9
Q

Undulant epidermal hyperplasia

A

verrucae (common to both forms)

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10
Q

Blue-gray elastic fibers

A

actinic keratosis

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11
Q

Keratin pearls

A

squamous cell carcinoma

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12
Q

elevated serum creatine kinase

A

muscular dystrophy

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13
Q

dystrophin

A

Duchenne or Becker muscular dystrophy

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14
Q

pseudohypertrophy of calves

A

Duchenne or Becker muscular dystrophy

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15
Q

red granular stuff in sarcoplasm (ragged red fibers)

A

mitochondrial myopathy

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16
Q

para-crystalline “parking lot inclusions” in the cristae of mitochondria

A

mitochondrial myopathy

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17
Q

PAX3-FKHR gene fusion

A

rhabdomyosarcoma

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18
Q

its worse to be a man

A

melanoma

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19
Q

tadpole and strap cells

A

rhabdomyosarcoma

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20
Q

a1 or a2 type 1 collagen mutation

A

osteogenesis imperfecta

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21
Q

Blue sclera

A

Osteogenesis imperfecta TYPE 1!

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22
Q

Point mutation (gain of function) in FGFR3

A

Achondroplasia

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23
Q

Increased osteoclasts

A

Type 1 (postmenopausal) osteoporosis

24
Q

Dowager’s hump

A

aka kyphosis. Osteoporosis

25
Q

Decreased osteoblasts

A

Type 2 (senile) osteoporosis

26
Q

diffuse pain, aspirin doesn’t help

A

osteoblastoma

27
Q

aspirin helps

A

osteoid osteoma

28
Q

central radiolucent nidus, rim of sclerotic bone

A

osteoid osteoma or osteoblastoma

29
Q

elevated serum alkaline phosphatase

A

osteosarcoma

30
Q

lifted periosteum –> Codman Triangle

A

osteosarcoma

31
Q

monosodium urate crystals

A

gout

32
Q

intraparenchymal vessel rupture

A

intracerebral hemorrhage

33
Q

berry aneurysm

A

subarachnoid hemorrhage

34
Q

middle meningeal artery rupture

A

epidural hematoma

35
Q

kicked in the side of the head

A

epidural hematoma

36
Q

fusiform and lenticular

A

epidural hematoma

37
Q

stroke from hypertension

A

intracerebral hemorrhage

38
Q

Pseudo-palisade arrangement of tumor cells

A

Glioblastoma multiforme

39
Q

whorled pattern of concentrically arranged spindle cells

A

meningioma

40
Q

psammoma bodies

A

meningioma

41
Q

gamma globulin in CSF

A

MS

42
Q

SORL-1

A

Late onset Alzheimer’s

43
Q

E2

A

good

44
Q

E4

A

bad (Alzheimer’s)

45
Q

Presinilin-1

A

Early onset Alzheimer’s

46
Q

beta-amyloid

A

Alzheimer’s

47
Q

tau protein

A

neurofibrillary tangle - Alzheimer’s

48
Q

you get hit in the head, you think you are ok, then you die

A

epidural hematoma

49
Q

2/3 have mutated RB gene, many also have mutated p53

A

osteosarcoma

50
Q

acute hypocorticism

A

Waterhouse-Friderichsen syndrome (complication of bacterial meningitis)

51
Q

HPV 2, 4

A

verruca vulgaris

52
Q

HPV 3, 10

A

verruca plana

53
Q

mitotic figures above the basal layer

A

psoriasis

54
Q

thin or absent stratum granulosum

A

psoriasis

55
Q

neutrophils in stratum corneum

A

psoriasis

Pathology Pt. 5 (7 decks)

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