Buzz Words 1 Flashcards

1
Q

Pancytopenia, Hx of radiation, Down syndrome

A

ALL

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2
Q

Pancytopenia, Auer rods, DIC

A

AML

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3
Q

WBC>100,000, blast crisis, Splenomegaly

A

CML

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4
Q

Male, Lymphadenopathy, Infection, SMUDGE cells, Splenomegaly

A

CLL

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5
Q

Plaque like itchy skin BS: w/ cerebriform nuclei Pautrier microabscess

A

Mycosis Fungoides

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6
Q

RS cells, night sweats cervical lymphadenopathy

A

Hodgkins lymphoma

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7
Q

Small follicular= best prognosis

Large diffuse = worst prognosis

A

NonHodgkins lymphoma

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8
Q

Anemia, teardrop, dry tap on BM, assoc w/ CML, High RDW MCV

A

Myelofibrosis

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9
Q

Folicular Lymphoma

A

T (14,18)

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10
Q

Burkitt’s lymphoma

A

T (8,14)

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11
Q

Mantle lymphoma

A

T (11, 14)

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12
Q

Presence of proliferation centers

Smudge cells

A

CLL

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13
Q

Presence of Centrocytes, Centroblasts

A

Follicular Lymphoma

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14
Q

Difference bet Leukomoid reaction from CML

A

Leukomoid rx >50,000 High leukocyte alkaline phosphatase

CML >50,000 Low leukocyte alkaline phosphatase

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15
Q

Primary chemotherapeutic drug for ALL & AE

A

Asparaginase (pancreatitis)

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16
Q

Primary chemotherapeutic drug for CML & AE

A

Imatinib (Fluid retention, CHF)

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17
Q

Plasmacytoma, bizarre, multinucleated cells, flame cells, mott cells, russell bodies, dutcher bodies, rouleaux conformation

A

Multiple myeloma

18
Q

Multiple Myeloma

A
Monoclonal M protein spike; IgM
Hypercalcemia
Renal Insufficiency
Anemia
Bone lytic lesions/ Bone pain
19
Q

Ringed sideroblasts, Pseudopelger-huet cells, pawn ball megakaryocytes

A

Myelodysplastic syndrome

20
Q

Fibrotic obliteration of marrow space; Osteosclerosis; Leukoerythroblastosis; Teardrop cells/dacryocytes

A

Primary Myelofibrosis

21
Q

Proliferative disorder of dendritic cells

Birbeck granules

A

Langerhans cell Histiocytosis

Letterer-Siwe disease

22
Q

Gandy-Gamna nodules

A

Congestive Splenomegaly

23
Q

Lobulated, firm, gray-white masses
Swirling pattern of spindle-shaped cells; assoc w/ myasthenia gravis;
Paraneoplastic syndrome is Pure red cell aplasia

24
Q

Normoblasts, Reticulocytosis, Cholelithiasis

A

Hemolytic anemias

25
Mutations of ankyrin, band 3, spectrin, band 4.2 | spherocytes, splenomegaly
Hereditary Spherocytosis
26
Heinz bodies and Bite cells
G6PD deficiency
27
Sickled cells, Reticulocytosis, Target cells (Codocytes), Howell jolly bodies Autosplenectomy
Sickle Cell Anemia
28
Target cells (codocytes) Basophilic stippling, Anisocytosis, Poikilocytosis, Microcytic and hypochromic anemia
Thalassemia
29
Autoimmune Hemolytic anemia associated with IgG
Warm agglutinin
30
Autoimmune Hemolytic anemia associated with IgM
Cold agglutinin | Mycoplasma, mononucleosis
31
Macro-ovalocytes, Hypersegmented neutrophils
Megaloblastic anemia
32
Atrophy of fundic glands, intestinalization, atrophic glossitis
Pernicious anemia
33
Conditions with basophilic stippling
Thalassemia, Anemia of chronic disease, IDA, Lead poisoning
34
Hypocellular bone marrow with fat cells | Normocytic, normochromic anemia
Aplastic anemia
35
Mucosal bleeding, previously healthy individual, Spontaneous resolution
ITP
36
Hx of Thrombosis FAT RN
TTP
37
GP 1B platelet adhesion; Platelet decrease
Bernard Soullier
38
GP IIB/IIIA platelet aggregation; Platelet normal
Glanzmann's thrombasthenia
39
MC inherited bleeding disorder; Hx of patient who has spontaneous bleeding but more commonly, trauma (dentist, nadapa) & wont stop bleeding but no hx of joint immobility
Von Willebrand factor disease
40
Hx of consaguinity X linked recessive severe bleeding d/o
Hemophilia
41
Child w/ diarrhea for several days presenting w/ frequent nosebleeding & gumbleeding; Prolonged PT/PTT
Vit K deficiency
42
Increase fibrinogen, pregnant px w/ FDU | Septic patient who is bleeding all over
DIC