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MedChem2 > Buschauer > Flashcards

Buschauer Flashcards

1
Q

Parasympatholytika

WM

A

1

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2
Q

Wrkg. von Agonisten am M-Rezeptor

A

2

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3
Q

M-Rezeptoren

Eigenschaften

A

3

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4
Q

M-Rezeptortypen, Vorkommen, Effekte

A

4

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5
Q

Atropin-Struktur

A

5

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6
Q

Nachweis der äquatorialen OH-Gruppe von beta-Tropanol

A

6

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7
Q

Stereochemie

endo/exo

syn/anti

A

7

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8
Q

Atropin-racemat

Optimum

A

8

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9
Q

Dehydratisierung und anschließende Dimerisierung von Atropin

A

9

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10
Q

Atropin

Wirkung und Indikation

A

10

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11
Q

Parasympatholytika/ Anticholinergika

Indikation

A

11

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12
Q

Anticholinergika Stoffklassen

A

12

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13
Q

quarternisierte Atropin-Analoga

A

13

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14
Q

Haupt und Nebenprodukt bei Quaternisierung

A

14

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15
Q

Butylscopolaminiumbromid

stereochemie

A

15

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16
Q

Scopolamin Hydrolyseprodukte

A

16

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17
Q

Brechvorgang

A

17

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18
Q

Rezeptoren im Bereich der Atemwege

A

18

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19
Q

Aclidiniumbromid

A

19

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20
Q

Umeclidiniumbromid

A

20

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21
Q

Methanthelin

Verwendung

A

21

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22
Q

Antiasthmatika, COPD

3 Beispiele

A

22

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23
Q

Mydriatika

3 Beispiele

A

23

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24
Q

Schlemmscher Kanal Öffnung

A

24

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25
Q

Tolterodin

A

25

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26
Q

Fesoterodin

A

26

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27
Q

antonome Inervation der Harnblase

A

27

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28
Q

Pirenzepin

A

28

Telenzepin 10 mal stärker

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29
Q

papaverin synthese

A

29

30
Q

Coralyn-Reaktion

A

30

31
Q

Tiropramid

A
32
Q

Neurotrop-muskulotrope Spasmolytika

A
33
Q

Parasympathikus Sympathikus Wirkung

A

33

34
Q

NTs im NS

A

34

35
Q

GPCR gekoppelte Rezeptoren

A

35

36
Q

Adrenozeptoren

A

36

37
Q

Biosynthese von Adrenalin

A

37

38
Q

Biotransformation von NA

A

38

39
Q

Noradrenalin vs Adrenalin

A

39

40
Q

Rezeptorselektivität Adrenalin NA

A

40

41
Q

Wirkorte von Pharmaka

A

41

42
Q

Anwendung

Adrenozeptoragonisten

A
43
Q

Adrenalin-Anwendung

A

43

44
Q

Phenylethylamine - pks Werte

A

44

45
Q

Farbreaktion prim Amine mit Diethoxytetrahydrofuran und Dimethylaminobenzaldehyd

A
46
Q
A
47
Q

Struktur-Wirkungsbeziehung

A
48
Q

Vorteile von alpha sympathomimetika zu adrenalin

A

48

49
Q

phenylethylamine als alpha-sympathomimetika

beispiele

A

49

50
Q

Imidazoline

A

50

51
Q

Naphazolinsynthese

A

51

52
Q

Naphazolin

A

52

53
Q

Wirkung von Betablockern am Herzen und an den Gefäßen

A

53

54
Q

beta-sympathomimetika

A

54

55
Q

nicht selektive betasympathomimetika

A

55

56
Q

beta2 selektive Sympathomimetika

A

56

57
Q

reproterol

tulobuterol

pirbuterol

A

57

58
Q

LABA

A
59
Q

Asthma Therapie

A

59

60
Q

langwirkende beta2-sympathomimetika

therapieempfehlung

A

60

langwirksame b. werden nur bei schwerer asthma b. gegeben (keine bedarfsapplikation)

sonst gabe von kurzwirksamen b. mit langzeitbehandlung mit inhalierbaren glucocorticoiden

61
Q

Olodaterol

Vilanterol

A

61

62
Q

Indacaterol

A

62

63
Q

Fenoterol-Synthese

A

63

64
Q

Effekte von beta3 sympathomimetika

A

64

65
Q

mirabegron

A

65

66
Q

von adrenalin zu metamfetamin

A

66

67
Q

Ephedrin und Ameziniummetilsulfat

A

67

68
Q

Stereochemie Ephedrin

A

68

69
Q

Reaktionsverhalten von Ephedrin

A

69

70
Q

L-Ephedrin-Synthese

A

70

71
Q

Wirkung Amfetamin Metamfetamin

A

MedChem2 (3 decks)

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