Burn Injuries Flashcards

1
Q

functions of the skin

A
barrier (body fluids and infection)
temperature 
elasticity
appearance
sensory organ
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2
Q

layers of skin

A

stratum coreneum, epidermis, dermis, subcutaneous tissue

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3
Q

types of burn injury

A

thermal (flash, flame, scald)
chemical (can progress until flushed out or neutralized)
electrical
radiological (alpha, beta, gamma radiation)

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4
Q

severity of burn injury and how they are classified

A

depth - extent of skin and tissue destruction (superficial, partial thickness, full thickness)
total body surface area involved (rule of nines)

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5
Q

superficial burn 1st degree

A

depth - destruction of epidermis
pain level - very painful
appearance - red
characteristics - dry, flaky, will heal spontaneously in 3-5 days

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6
Q

partial thickness burn 2nd degree

A

depth - superficial or deep, epidermis up to deep dermal element
pain level - very painful
appearance - bright cherry red, pink or pale ivory, usually with fluid filled blistering
characteristics - hair follicle intact, may require skin graft

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7
Q

full thickness burn 3rd degree

A

depth - all of the epidermis, dermis, down into the subcutaneous tissue
pain level - little or no pain
appearance - khaki brown, white, or charred/cherry red is pediatrics
characteristics - loss of hair follicles, will require skin graft

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8
Q

fourth degree

A

depth - full thickness extending into muscle and bone

will require skin graft or amputation

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9
Q

rule of 9’s for adults

A
head = 9 %
upper extremities = 18% (each arm 9%)
trunk = 36% (front = 18%, back = 18%)
lower extremities = 36% (each leg 18%)
genitalia = 1%
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10
Q

rule of 9’s for pediatrics

A
head = 18%
upper extremities = 20% (each arm 10%)
trunk = 32% (front = 16%, back = 16%)
lower extremities = 28% (each leg 14%)
genitalia = 1%
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11
Q

burns that should be transferred to burn center

A

full thickness burns in any age group
partial thickness >10% TBSA
burns of special areas (extreme of age, burns of face, hands, feet, perineum or major joints, inhalation, chemical, electrical burns, those burns associated with co-existing disease)

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12
Q

determining mortality with age and TBSA

A

if the age of the patient plus the TBSA is greater than 115 the mortality is greater than 80%

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13
Q

in a closed space thermal injury think…

A

airway injury

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14
Q

electrical injury may lead to occult

A

severe fracture, hematoma, visceral injury, skeletal, cardiac injury, neurologic injury

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15
Q

signs and symptoms of airway complications

A

singed facial hair, facial burns, dysphonia/hoarseness, cough/carbonaceous sputum, soot in mouth/nose, swallowing impairment, oropharynx inflammation, CXR initially normal

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16
Q

inhalation injury refers to

A

damage to the respiratory tract or lung tissue from heat, smoke, or chemical irritants carried into the airway during inspiration

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17
Q

upper airway inhalation injury involvement

A

thermal damage to soft tissues of the respiratory tract and trachea can make intubation difficult
increased risk of glottic edema with injury and fluid resuscitation

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18
Q

lower airway inhalation injury involvement

A

pulmonary edema/ARDS develops 1-5 days post burn

pneumonia and pulmonary embolism > 5 days post burn

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19
Q

smoke inhalation occurs in conjunction with

A

face/neck burns and closed space fires

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20
Q

chemical pneumonitis occurs after

A

smoke/toxic fume inhalation

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21
Q

honeymoon period for smoke inhalation that will show clear CXR

A

1st 48 hours

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22
Q

symptoms of smoke inhalation

A

increased sputum and rales/wheezing

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23
Q

hypoxia in the first 36 hours after inhalational injury

A

high risk of pulmonary edema

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24
Q

hypoxia in day 2-5 after inhalational injury

A

expect atelectasis, bronchopneumonia, airway edema maximum secondary to sloughing of airway mucosa, thick secretions, distal airway obstruction

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25
Q

hypoxia >5 days post inhalational injury

A

nosocomial pneumonia, respiratory failure, ARDS

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26
Q

implications of circumferential burns of chest/upper abdomen

A

restricted chest wall motion as eschar contracts and hardens

27
Q

if inhalation injury or facial burns are suspected or known

A

intubate and secure the airway early!

28
Q

ETT indicated in a burn patient if

A

pediatric, massive burn, stridor, respiratory distress, hypoxia/hypercarbia, altered level of consciousness, if deterioration likely

29
Q

safest approach for intubation in burn patient

A

fiberoptic intubation under adequate topical anesthesia

30
Q

treatment of hypoxia in burn patient with inhalational injury

A

PEEP, airway humidification, bronchial suctioning/lavage, bronchodilators, antibiotics, chest physiotherapy

31
Q

restriction of respiratory excursion may necessitate

A

escharotomy

32
Q

carbon monoxide is ____ times the affinity for Hgb as O2

A

200

33
Q

CO shifts the hemoglobin dissociation curve to the ___

A

left impairing O2 unloading at the tissue level

34
Q

CO interferes with

A

mitochondrial function, uncouples oxidative phosphorylation, reduces ATP production = metabolic acidosis

35
Q

carbon monoxide treatment

A

high FiO2

hyperbaric chamber if > 30% and patient is hemodynamically and neurologically stabilized

36
Q

a COHbg greater than ___ is incompatible with life

A

60%

37
Q

CO < 15-20% symptoms

A

HA, dizziness, confusion

38
Q

CO 20-40% symptoms

A

nausea, vomiting, disorientation and visual impairment

39
Q

CO 40-60% symptoms

A

agitation, combative, hallucinations, coma, shock

40
Q

blood cyanide levels of ____ confirm diagnosis of cyanide toxicity

A

> 0.2 mg/L

41
Q

lethal blood cyanide level

A

1.0 mL/L

42
Q

cyanide has a half life of

A

60 minutes

43
Q

treatment for cyanide toxicity

A

O2, hydroxycobalamine, amyl nitrate, sodium nitrate, thiosulfate

44
Q

burns and systemic effects

A

release of inflammatory mediators locally and systemically = edema
increase in microvascular permeability = fluid leak and loss of proteins
increased intravascular hydrostatic pressure and decreased interstitial hydrostatic pressure
increased interstitial osmotic pressure

45
Q

cardiovascular stresses with burn injury

A

severe decrease in CO lasts 1st 24 hours
circulation tumor necrosis factor = myocardial depression
diminished response to catecholamines
increased microvascular permeability = hypovolemia
intense vasoconstriction compensation = decrease flow to tissues
decreased tissue O2 supply and coronary blood flow

46
Q

after 24-48 hours of burn patients are in a ____ state

A

hyperdynamic state (high output CHF), CO is 2x normal

47
Q

metabolism in burn patient

A

increased metabolic rate is proportional to TBSA burned
increased core body temp reflects increased metabolic thermostat, loss of skin = loss of vasoactivity, piloerection, insulation functions

48
Q

GI complications

A

ileus, ulceration, cholecystitis

49
Q

Renal complications

A

decreased GFR, RBF, loss of Ca, K, Mg with retention of Na, H2O

50
Q

endocrine complications

A

increased corticotropin, ADH, renin, angiotensin, aldosterone, increased glucagon, insulin resistance, hyperglycemia

51
Q

blood and coagulation complications

A

increased viscosity, increase in clotting factors including fibrinogen, V and VIII, fibrin split products at risk of DIC development, HCT usually decreases (RBCs decreased half life)

52
Q

fluid resuscitation 1st 24 hours

A

crystalloid only
replace with 2-4 mL/kg for each 1% TBSA burned
titrate fluids to U/O 0.5 - 1 mL/kg/hr

53
Q

over aggressive fluid resuscitation can lead to

A

airway edema, increase chest wall restriction, and contribute to abdominal compartment syndrome

54
Q

fluid resuscitation after 1st 24 hours

A

use colloids at 0.3-0.5 mL/kg/% burn with 5% dextrose in water

55
Q

Parkland formula

A

4 mL of LR/kg/% burn/1st 24 hours

56
Q

Modified Brooke formula

A

2 mL of LR/kg/% burn/1st 24 hours

57
Q

calculated volumes are given in the 1st 24 hours

A

50% first 8 hours
25% second 8 hours
25% third 8 hours

58
Q

goals of resuscitation

A
urine output = 0.5-1 mL/kg/hr
HR = 80-140 
MAP = >60 in adults
base deficit = < 2
normal Hct
59
Q

what can we give if fluids are not enough?

A

low dose Dopamine 5 mcg/kg/min

60
Q

anesthesia considerations/concerns

A
often need repeated surgeries
maintain Hct
coagulopathy
temperature
fluids and electrolytes
hypermetabolic state 
increased risk for GI ileus
61
Q

challenges for anesthesia in burn patients

A

burned tissue = limited access for ECG, SaO2, PNS, NIBP
need large bore IV
compensate for evaporative/exposure heat loss (room temp 28-32 C)
minimize blood loss (topical/SQ epi, only 15-20% TBSA each procedure, tourniquets)
treat complications of massive transfusion (coagulopathy, hypocalcemia)

62
Q

anesthesia considerations for high voltage electrical injury

A

follows path of least resistance (bone most resistant)
cardiac arrhythmias
respiratory arrest
seizure
fractures
muscle damage = myoglobinurea and renal failure

63
Q

muscle relaxants in 1st 24 hours

A

unaltered response to depolarizing and non-depolarizing muscle relaxants

64
Q

muscle relaxants in 24 hours to 1 year post burn

A
avoid succinylcholine (massive release of K)
may be due to the proliferation of acetylcholine receptors along the entire muscle membrane 
resistance to most NDMR if >30% TBSA burned