Bugs and their Drugs Flashcards
Enterococcus faecalis Serious Infection
Ampicillin ( or Penicillin G) = Gentamicin or Streptomycin OR Vancomycin = (Gentamicin or Streptomycin), Daptomycin, linezolid, tigecycline
Enterococcus faecalis UTI
ampicillin, amoxicillin OR fosfomycin, nitrofurantoin
Enterococcus faecium
Linezolid, quinupristin/dalfopristin, daptomycin, tigecycline
Staph aureus/epidermidis (MSSA)
Nafcillin or oxacillin, Bacrim, FGC, BL
Staph aureus/epidermidis Hospital Aquired (MRSA)
Vancomycin +/- (gentamicin or rifampin) or daptomycin, linezolid, tigecycline, Bacrim, quinuprisin-dalfoprisin
Staph aureus/epidermidis Community Aquired (MRSA)
Clindamycin, Bacrim, Doxycycline or Daptomycin, linezolid, telavancin, tigecycline, or vancomycin
Streptococcus (Group A,B,C,G, strep bovis)
Penicillin G, Penicillin V, ampicillin or FGC, erythromycin, azithromycin, clarithromycin
Streptococcus pneumoniae Penicillin sensitive
Penicillin G, Penicillin V, ampicillin or FGC, doxycycline, azithromycin, clarithromycin, erythromycin
Strep pneumoniae Penicillin intermediate
High dose penicillin (12 million units/day for adults), ceftriaxone, cefotaxime
Strep pneumoniae Penicillin resistant
Vancomycin +/- rifampin, or per sensitivities: Cefotaxime, ceftriaxone, levofloxacin, moxifloxacin, gemifloxacin
Strep viridans
Penicillin G -/+ gentamicin, or, cefotaxime, ceftriaxone, erythromycin, azithromycin, clarythromycin, or vancomycin +/- gentamycin
Moraxella Catarrhalis
Amoxicillin-clavulanate, ampicillin-sulbactam, or, erythromycin, azithromycin, clarythromycin, doxycycline, SGC, cefotaxime, ceftriaxone, TGCPO
Neisseria gonorrhoeae Disseminated infection
Ceftriaxone or cefotaxime, Follow up: cefpodoxime, ciprofloxacin, levoflocacin
Neisseria gonorroeae Uncomplicated infection
Ceftriaxone, Cefotaxime, or cefpodoime
or Ciprofloxacin, levofloxacin
Neisseria meningitides
Penicillin G, Cefotaxime, ceftriaxone
Clostridium perfringens
Penicillin G +/- clindamycin, or metronidazole, clindamycin, doxycycline, cefazolin, cabapenem
Clostridium difficile
Oral metronidazole, oral vancomycin