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Neuro > BTR > Flashcards

BTR Flashcards

1
Q

Meissener corpuscles

A

MC- most common(numerous)
In Non Hairy skin only
Messi- fast moving touch and two point discrimination

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2
Q

Pacinian corpuscles

A

Pc -largest receptor as largest star
But sensitive
And High frequency vibration
Onion shape

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3
Q

Hair end organ

A

Fast
Hair movement

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4
Q

Merkel cells

A

Slow adaptation
Epidermis
Edge
Braille

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5
Q

Skin stretch, pressure
Max in joint capsule

A

Ruffini’s corpuscles

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6
Q

C fibers

A

Itching and slow pain
Via Subs p

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7
Q

Fast adapting receptor

A

Mc
Pc
Hair end organ

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8
Q

Erlanger Grasser classification

A

A (alpha beta gamma delta)
B
C

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9
Q

A alpha

A

Propioception
Somatic motor
120 m/sec

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10
Q

A beta

A

Beta treated with touch and pressure

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11
Q

A gamma

A

Efferent to muscle spindle

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12
Q

A delta

A

Fast pain , temp (cold)

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13
Q

C fibers

A

Slow pain , warm temp
Post ganglionic symp

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14
Q

Local anesthetic sensitivity

A

A gamma >delta>alpha>beta>B>C

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15
Q

Pressure sensitivity

A

A>B>C

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16
Q

Hypoxia

A

B>A>C

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17
Q

Awake EEG Wave

A

Beta

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18
Q

Awake eyes closed wave?

A

Alpha

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19
Q

Stage N1 (5%)

A

Theta

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20
Q

Problem solving eeg

A

Gamma wave

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21
Q

Stage N2 eeg

A

Sleep spindles and K complexes

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22
Q

Stage N3 eeg

A

Delta

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23
Q

REM SLEEP EEG

A

Beta , PGO

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24
Q

Night mares and night terror

A

Mares - Memory
In REM

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25
Q

Stage NREM

A

N1
N2 Bruxism
N3 Night walking
Nocturnal enuresis
Night terrors

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26
Q

Sleep changes in elderly

A

Decrease in REM sleep
Decrease N3

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27
Q

Sleep changes in depression.

A

Increase in REM sleep time
Decrease Rem Latency
Decrease N3 repeated night time awakenings
Early morning awakening

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28
Q

Sleep Changes in narcolepsy

A

Decrease REM LATENCY

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29
Q

SNpc

A

Dopamine
Main regulator of basal ganglia

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30
Q

STN

A

Glutamate as Nt
Contralateral hemiballismus

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31
Q

Caudate disorder

A

Chorea
Gaba release

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32
Q

Globus pallidus

A

Athetosis

(Global athelete)

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33
Q

Hypothalamic
Lateral nucleus

A

Hunger and anger
Mediated by Grehlin

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34
Q

Thalamic nuclei
VPL

A

ST/DC —-> BODY(Pain , temp , touch) and Vibration —>3,1,2

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35
Q

Thalamic nuclei
VPM

A

ST/DC—>FACE/TASTE—>3,1,2

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36
Q

LGN

A

Optic tracts/SC—> Vision—>1° visual cortex(17)

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37
Q

MEDIAL GENICULATE NUCLEUS

A

LL/IC—>HEARING—->AUDITORY CORTEX

38
Q

Thalamic nuclei
Ventral anterior/lateral nucleus

A

BG/cerebellum—>motor cortex

39
Q

Hypothalamic nucleus
Lateral

A

Hunger and anger (by Grehlin)

40
Q

Hypothalamic nucleus
VM

A

Satiety (leptin)

41
Q

Hypothalamic nucleus
Anterior

A

Ac –> cooling

42
Q

Hypothalamic nucleus
Suprachiasmatic

A

Circadian rythm(melatonin)

43
Q

Hypothalamic nucleus
SON AND PVN

A

SAD(ADH)
POX(OXYTOCIN)

44
Q

Hypothalamic nucleus
Preoptic nucleus

A

Sexual response(GnRH)
Related to kallman sx.

45
Q

Gaba agonist

A

BZD(Inc freq)
Topiramates
Phenobarbi(durates)

46
Q

Increase GABA RELEASE

A

Pregabalin
Gabapentin

47
Q

Gaba reuptake inhibitor

A

Tiagabine

48
Q

GABA transaminase inhibitor

A

Vigabatrin

49
Q

Vigabatrin

A

Visual field defect
Gaba transaminase inhibitor

50
Q

AMPA receptor blocker

A

PerAMPANEL

51
Q

NMDA RECEPTOR blocker

A

FELBAMATE

52
Q

K+ channel opener

A

Retigabine / Ezogabine

53
Q

SV2A RECEPTOR BLOCKER

A

Levetiracetam
Block exostosis of Na and Ca synaptic vessicle

54
Q

Ethosuximide
Gapapentin

A

Ca channel blocker

55
Q

Carbamazapine s/e

A

Ataxia
Blood dyscracias
Cleft lip and palate
Cyt p450 induction
Diplopia
SIADH(MORE WITH OXCARBAZEPINE)¤
SJS

56
Q

Phenytoin side effect

A

P P450 Indn , pseudolymphoma
H irsuitism
Enlarged gums
Nystagmus
Yellow brown skin
Teratogenicity
Osteopenia
Inhibited folate absorption
Neuropathy

57
Q

Lamotrigine

A

SJS
Hemophagocytic lymphohistiocytosis

58
Q

Doc Focal seizures

A

Carbamazepine

59
Q

D o c focal seizures in elderly

A

Lamotrigine

60
Q

DOC trigeminal Neuralgia

A

CBZ

61
Q

DOC
TYPICAL ABSENCE SEIZURE
Atypical

A

Ethosuximide
Valproate

62
Q

DOC
INFANTILE SPASM

A

ACTH

63
Q

DOC
INFANTILE SPASM IN TSC

A

Vigabatrine

64
Q

DOC NEONATAL SEIZURE

A

Phenobarital

65
Q

DOC
FEBRILE SEIZURE

A

Diazepam

66
Q

DOC
STATUS EPILEPTICUS

A

Lorazepam

67
Q

BZD APPROVED IN LGS

A

Clobazam

68
Q

DOC GTCS/JME/LGS

A

Valproate

69
Q

Seizure DOC IN PREGNANCY

A

Levitiracetam/lamotrigine

70
Q

Decussation at spinal cord and asc contralateral

A

Lateral Spinothalamic tract
Pain and temp

71
Q

Ascends I/L
Decussate at medulla as medial leminuscus

A

Dorsal column tract

72
Q

Desends from 1° motor cortex
Decussate at medulla
Go to AHC

A

Corticospinal tracts

73
Q

Brown sequard

A

LMN AT LEVEL OF LESION
BELOW THE LESION
I/L CORTICOSPINAL AND DORSAL COLUMN
C/L SPINOTHALAMIC LOSS

74
Q

Ant 2/3 rd cord affected

A

Ant spinal artery infarct
Only DC is working

75
Q

Post column affected with DRG

A

Tabes dorsalis
(Tertiary syphillis)
Loss of joint position
Argyl robertson pupil
Lancenating pain

76
Q

Cape ljne loss of temp and sensation

A

Syringomyelia

77
Q

DC and corticospinal loss

A

SACD IN B12 DEF , CU Def , HIV

78
Q

AHC AFFECTED

A

Acute flaccid paralysis
In poliomyelitis

79
Q

B/l symmetrical AHC

A

LMN PALSY
WERNIG HOFFMAN DISEASE/SPINAL MUSCULAR ATROPHY
(FLOPPY BABY)

80
Q

UMN + LMN

A

ALS
(LEU GEHRIG DISEASE)

81
Q

ALS

A

Riluzole
(NMDA blocker)
Edavarone

82
Q

SCN1A

A

Dravet syndrome
Doc Valproate

83
Q

EPM2A DEFECT

A

Lafora ds.

84
Q

1st drug in seizure (early se)

A

Iv BZD lorazepam 0.1 mg/kg

Then Phenytoin

85
Q

Established SE

A

IV midaz or propofol

Then any other anti epileptic

86
Q

Refractory Status epilepticus

A

Pentobarbitone 5 mg/kg

87
Q

Myotonia congenita

A

CLCN1 DISORDER

88
Q

Hyperkalemic periodic paralysis

A

SCN4A Na channel problem

Kalemic not related to potassium

89
Q

Hypokalemic periodic parslysis

A

CaCNA1S Ca channel
SCN4A

90
Q

Anderson tawil sx

A

KCNJ2

Neuro (3 decks)

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