bs+scp

Question 1

sudden transient loss of muscle tone

Answer 1

cataplexy

Question 2

varencicline moa

Answer 2

partial nicotinic receptor agonist
(80% more effective than bupropion)
ass with suicidal thoughts

Question 3

valproate during pregnancy causes

Answer 3

spina bifida, hypospadias

Question 4

SSRI discontinuation syndrome fx

Answer 4

flu like
dizziness
vivid dreams
irritability
crying spells
sensory symptoms

particularyl common in paroxetins and venlafaxine

Question 5

huntingdon’s disease gene

Answer 5

IT15

Question 6

alzheimers disease gene

Answer 6

APOE

Question 7

CADSIL fx

Answer 7

migrains, TIA, Stroke
35-55
subcortical dementia ass with pseudobulbar palsy
urinary incontinence
Notch 3 gene

Question 8

Goldstein-Scheerer Object Sort Test

Answer 8

used to assess abstract/concrete thinking and how well concepts are formed.

Question 9

sedatives recommended in hepatic impairment

Answer 9

Lorazepam
Oxazepam
Temazepam
Zopiclone

Question 10

senile pupil

Answer 10

characteristically small pupil sometimes seen in older people which fails to dilate in the dark
sluggish

Question 11

histrionic fx

Answer 11

Inappropriate sexual seductiveness
Need to be the centre of attention
Rapidly shifting and shallow expression of emotions
Suggestibility
Physical appearance used for attention seeking purposes
Impressionistic speech lacking detail
Self dramatization
Relationships considered to be more intimate than they are

Question 12

borderline fx

Answer 12

Efforts to avoid real or imagined abandonment
Unstable interpersonal relationships which alternate between idealization and devaluation
Unstable self image
Impulsivity in potentially self damaging area (e.g. Spending, sex, substance abuse)
Recurrent suicidal behaviour
Affective instability
Chronic feelings of emptiness
Difficulty controlling temper
Quasi psychotic thoughts

Question 13

Risk factors for SIADH include

Answer 13

Being elderly
Being female
Being a smoker
Having medical co-morbidity
Polypharmacy

Question 14

least developed sense at birth

Answer 14

vision- 20-30 cm distance focus
can see lines where light and dark meet
Can see mothers face at 1 week post term

Question 15

effect of lithium on FBC

Answer 15

raises white cell count

Question 16

Autosomal Dominant

Answer 16

Neurofibromatosis type 1 and 2, tuberous sclerosis, achondroplasia, Huntington disease, Noonan’s syndrome

Question 17

Autosomal Recessive

Answer 17

Phenylketonuria, homocystinuria, Hurler’s syndrome, galactosaemia, Tay-Sach’s disease, Friedrich’s ataxia, Wilson’s disease, cystic fibrosis

Question 18

X-Linked Dominant

Answer 18

Vitamin D resistant rickets, Rett syndrome

Question 19

X-Linked Recessive

Answer 19

Cerebellar ataxia, Hunter’s syndrome, Lesch-Nyhan

Question 20

Mitochondrial

Answer 20

Leber’s hereditary optic neuropathy, Kearns-Sayre syndrome