Brunner

Question 0

What was wrong with the males in the family?

Answer 0

Borderline mental retardation and abnormal violent behaviour.

Question 1

What did they want to explain?

Answer 1

The behaviour of a large family in the Netherlands.

Question 2

What abnormal violent behaviour did they display?

Answer 2

Impulsive aggression, arson, attempted rape and exhibitionism

Question 3

How many members of the family were involved?

Answer 3

5

Question 4

How was data collected?

Answer 4

Analysis of urine samples over a 24-hour period

Question 5

What did the tests show?

Answer 5

Disturbed monoamine metabolism associated with a deficit of the enzyme monoamine oxidase A

Question 6

What was found in the X chromosome of the gene responsible for production on MAOA?

Answer 6

Point mutation

Question 7

What is point mutation?

Answer 7

A single point mutation occurs when a single nucleotide is replaced with a different one

Question 8

What is a nucleotide?

Answer 8

One of the structural components of DNA and RNA.