Brpt 04 Flashcards
Hypoxia
Lack of oxygen at the tissue level; does not meet cellular needs
Hypoxemia
Lack of oxygen in the arterial blood
Hyperoxia
Increased levels of oxygen to the tissues usually due to the use of supplement O2
Hypocapnea (hypocarbia)
Decrease in CO2 in the blood
Hypercapnea (hypercarbia)
Increase in CO2 in the blood
Cyanosis
Bluish tinge of skin and mucous membrane visible when you have 5 Gm/100 ml or 5 % of blood of dissociated hemoglobin
Secondary polycythemia
Increased production of RBCs. Compensatory mechanism to decreased levels of oxygen in the blood
A/C membrane has three main barriers:
Alveolar epithelium
Interstitial space and its structures
Capillary endothelium
Where is the highest CO2 level
In the venous blood
Hypoxemia aka hypoxic hypoxia
In adequate delivery of oxygen to the lungs or from the lungs got the blood
Causes of hypoxemia (hypoxic hypoxia)
Hypoventilation
High altitude
Shunt
V/Q mismatch
Does Hypoxemia (hypoxic hypoxia) respond to oxygen therapy?
Yes except for shunts because of no blood flow
Anemic Hypoxia
Hemoglobin deficiency
Anemic Hypoxia causes
Carbon monoxide poisoning, loss of hb
Does Anemic hypoxia respond well to oxygen therapy?
Yes
Circulatory hypoxia
Stagnant or hypoperfusion or low blood flow
Circulatory hypoxia causes
Ischemia, cardiac pump failure, shock
Does Circulatory hypoxia respond to oxygen therapy?
Yes as long as the pump is working. Do not withhold oxygen from patient
Histotoxic hypoxia (dysoxia)
Poisoning of the cellular oxygen utilization mechanism has occurred
Histotoxic hypoxia (dysoxia) example
Cyanide poisoning
Does histotoxic hypoxia (dysoxia) respond to oxygen therapy?
No
Acute hypoxia sign/symptoms
Tachypnea, increase depth of rr, tachycardia, arrhythmia, confusion
Chronic hypoxia signs/symptoms
Increased AP diameter on CXR and secondary polycythemia
Indications for oxygen use
PaO2 <60mmHg or SaO2 <90%