Bronchiectasis Flashcards

1
Q

Types of bronchiectasis

A

Cylindrical, varicose and cystic

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2
Q

Clinical Phenotypes

A

Psuedomonas aeruginosa = 16%
Other chronic infection = 24%
Daily Sputum = 33%
Dry Bronchiectasis = 27%

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3
Q

Investigations for bronchiectasis

A
FBC, Ig levels
Sweat test
Sputum culture, including mycobacteria
Serology for aspergillus species
Spirometry
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4
Q

Treatable causes

A
CVID
ABPA
MAC infections
TB
Airway obstruction
IBD
RA
Aspiration
COPD
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5
Q

Treatment of Bronchectasis

A

Pulmonary rehabilitation
Pseudomonas eradication
Antibiotic therapy - 10 days
Physiotherapy for airway clearance techniques

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6
Q

Role of macrolides?

A

Immunomodulatory and antibacterial effect

Useful in patients with recurrent infections - decreases exacerbation frequency but nil change in disease course

Must exclude MAC colonisation

Azithromycin 500mg TDS

S/E: GIT pain and diarrhoea and QT prolongation

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7
Q

Pseudomonas eradication protocol

A

Ciprofloxicin 750mg BD for 2 weeks

–> 80% eradication
Decreases exacerbation frequency

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