Bronchiectasis Flashcards

1
Q

What is bronchiectasis?

A

Obstructive lung disease characterised by** permanent** dilatation of of bronchi/oles caused by destruction of muscle & elastic tissue.

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2
Q

What are the causes of bronchiestasis?

A

Congenital;

  • Cystic fibrosis

Post-infection;

  • Pneumonia, TB, HIV, measles, pertussis, bronchiolitis

Other;

  • Bronchial obstruction (tumour, foreign body)
  • Allergic bronchopulmonary aspergillosis

Main causative organisms;

  • H. influenzae
  • Staph. aureus
  • Strep. pneumoniae
  • Pseudomonas aeruginosa.
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3
Q

What are the clinical features of bronchiectesis?

And what are some complications?

A

Symptoms;

  • Persistent cough & copious purulent sputum & intermitten haemoptysis

Signs;

  • Finger clubbing
  • Coarse inspiratory crepitations
  • Wheeze (asthma, COPD, ABPA)

Complications;

  • Pneumonia
  • Pleural effusion
  • Pneumothorax
  • Haemoptysis
  • Cerebral abscess
  • Amyloidosis
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4
Q

What investigations can you perform for bronchiectasis?

A
  • Sputum culture
  • CXR
    • Cystic shadows
    • Thickened bronchial walls (tramline & ring shadows)
  • Thin section high-resolution CT (HRCT); assess extent & distribution of disease
  • Spirometry; obstructive pattern
    • Bronchoscopy; locate site of haemoptysis/ exclude obstruction
  • Others; serum immunoglobulins, CF sweat test, Aspergillus precipitins or skin-prick test
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5
Q

How would you manage bronchiectasis?

A
  • Postural drainage - twice daily
  • Antibiotics
  • Bronchodilators
  • Surgery (if localized disease/ severe haemoptysis)
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