breathing rate and homeostatis Flashcards
respiratory quotient
ratio of amount of CO2 produced by the body to the amount of oxygen consumed
what can cause a decrease in RQ (avg normally 0.8)
excess fat intake or diabetes
starvation
inspiratory muscles
diaphragm
external intercostals
accessory muscles:
scalene muscles
sternomastoids
muscles of neck
muscles of expiration (forced)
rectus abdominus
internal and external obliques
internal intercostals
dorsal respiratory group (DRG)
controls the diaphragm, involved in inspiration
ventral respiratory group (VRG)
controls intercostals muscles, involved in inspiration and expiration
apneustic centre
modulates DRG function to prevent over-expansion, loss of this area causes apneusis
pneumotaxic centre
modulated DRG, increasing RR and decreasing VT (tidal vol) to maintain MV (mechanical ventilation)
how is oxygen carried in the blood
bound to haemoglobin (97%)
dissolved in blood (3%)
how is carbon dioxide carried in the blood
as bicarbonate (90%)
as dissolved CO2 (5%)
as carbamino (5%)
what can testing A-a gradient be useful for
recognising shunts and give an idea of VQ mismatch
lung compliance
vol change per unit pressure change (mls/cmH2O)
hypoxemia causes
alveolar ventilation (V) and pulmonary perfusion (Q) mismatch
intrapulmonary shunt
hypoventilation
main types of acid-base imbalance
respiratory acidosis
metabolic acidosis
metabolic alkalosis
respiratory alkalosis