Breathing Flashcards

1
Q

What are the applications of flexible bronchoscopy?

A

Therapeutic and Diagnostic

  1. visualisation of pathology
  2. sampling eg Bronchoalveolar lavage
  3. Difficult intubations
  4. Direct opening eg retrieval or stenting
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2
Q

Why might you pick rigid vs flexible bronchoscopy?

A

Rigid allows for greater suction and more instrumentation

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3
Q

What is Tidal Volume? and roughly what value is it?

A

Tidal Volume = volume in and out in one cycle

Roughly 7ml/kg ~500ml

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4
Q

What are inspiratory and expiratory reserve volumes?

A

This is the volume above and below quiet respiration and tidal volume
IRV is around 3L
ERV is around 1.3L

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5
Q

What is the Inspiratory Capacity?

A

Inspiratory Capacity = Tidal Volume + Inspiratory Reserve Volume

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6
Q

What is Vital Capacity?

A

Vital Capacity = Tidal Volume + both inspiratory and expiratory reserve volumes

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7
Q

What is Residual Volume?

A

Residual Volume = gas remaining after maximum expiration

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8
Q

What is Total Lung Volume?

A

Total Lung Volume = Vital Capacity + Residual Volume

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9
Q

What is Function Residual Capacity? and what increases it?

A

Functional residual capacity = Expiratory reserve + respiratory volume ~3L
This is increased in:
1. COPD/Asthma (obstructive)
2. PEEP eg CPAP

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10
Q

How do you differentiate obstructive vs restrictive lung disease

A

Use spirometry:
Obstructive: FEV1/FVC < 0.8
Restrictive: FEV1/FVC > 0.8

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11
Q

What is atelectasis?

A

Atelectasis is collapse (loss of gas) in any section of lung

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12
Q

What is absorption atelectasis?

A

Oxygen is absorbed more readily than nitrogen

over oxygenation causes collapse

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13
Q

What are the causes of post-op atelectasis?

A
  1. Increased secretions
  2. Pain causing reduced tidal volume
  3. Over oxygenation and absorption atelectasis
  4. Patient: High BMI, Smoking, COPD
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14
Q

What is Bronchiectasis?

A

Irreversible dilatation of the bronchi (due to infection) and impaired clearance of secretions
Presents clinically as obstructive

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15
Q

What are the common causes of bronchiectasis and how can they be categorised?

A

Congenital:
1. Cilliary Dyskinesia (Kartagener’s)
2. Cystic Fibrosis (most common)
3. Immunodeficiency (multiple infections)
Acquired:
1. Repeated acute and chronic inflammation (eg infection)
2. Obstruction (eg tumours/foreign body)
3. Others eg aspergillosis, Rheumatoid, UC

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16
Q

What is the management of bronchiectasis?

A
  1. Treat underlying cause (eg infections/airway obstruction)
  2. Medical (eg bronchodilators and steroids)
  3. Symptomatic (eg physio)
  4. Definitive ( eg surgery - RARE)
17
Q

What is the definition of pneumonia?

A

Inflammatory condition of the lung, characterised by exudative consolidation

18
Q

What are the phases of lobar pneumonia?

A
  1. Acute congestion (to day 2): hard, firm, lots of exudate
  2. Red hepatisation (to day 4): firm, red, consolidated with red cells and inflammatory cells
  3. Grey hepatisation (to day 6): firm, grey, consolidated with fibrin
  4. Resolution (day 8 to 3 weeks): macrophages break down exudate
19
Q

What are the common complications of pneumonia?

A
  1. Type I respiratory failure
  2. Pleuritis (extensive adhesions)
  3. Pleural effusion
  4. Empyema
  5. Abscess (local or systemic)
  6. Sepsis
20
Q

What is the definition of ARDS?

A
  1. Respiratory failure + persistent inflammatory disease

2. Causes: reduced compliance, hyperaemia, pulmonary oedema

21
Q

What are the phases of ARDS?

A
  1. Inflammatory: local complement, immune cells, increased permeability
  2. Proliferative: increased dead space with fibrosis and scarring
  3. Progressive: extensive fibrosis and loss of alveolar structure
22
Q

Which cells produce surfactant?

A

Type 2 Pneumocytes

23
Q

How do you manage ARDS?

A
  1. Manage initial insult
  2. Nutritional Support
  3. Mechanical ventilation to eliminate CO2
  4. Smaller tidal volumes
  5. Prone positioning
  6. Fluid management
  7. Nitric Oxide for vasodilatation
24
Q

Define Flail Chest

A

3 or more ribs broken in 2 or more places

25
Q

How does a flail segment present?

A

Paradoxical movement during respiratory cycle

Causes reduced tidal volumes and atelectasis

26
Q

What is a sucking chest wound?

A

Open chest wall injury larger than 2/3rds of trachea.
air preferentially enters via this.
causes a large tension pneumothorax
treated with a flutter valve

27
Q

What are the risk factors for DVT?

A
Intrinsic:
1. Age
2. Cancer
3. Dehydration and sepsis
4. Haematological
5. Previous thrombotic events
6. Endocrine eg COCP
Surgical:
1. Stasis from major surgery and immobilisation
28
Q

Where do DVTs usually occur?

A

Deep veins of the calves

venous plexus in soleus.

29
Q

What are you likely to see in obs and ABG of a PE?

A

hypoxia - V/Q mismatch due to decreased blood flow
hypocarbia - due to hyperventilation
tachycardia - due to right sided ventricular strain

30
Q

what is the treatment of a PE?

A
  1. LMWH
  2. Anticoagulation
  3. Thrombolytic agents
  4. Catheter dislodge or surgery
31
Q

What are the normal ranges of PaO2 and PaCO2?

A

PaO2: 10.6 - 13.3kPa
PaCO2: 4.7 - 6.0kPa

32
Q

How do you classify Respiratory Failure?

A

Type 1: low O2 - V/Q mismatch. This causes increased CO2 which leads to hyperventilation. PaO2 <8kPa

Type 2: ventilatory failure. alveolar hypoventilation causing hypercarbia. PaCO2 > 6.7kPa.

Mixed = Type 1 causing tiredness and leading to type 2

33
Q

Examples of Type 1 Respiratory failure?

A

Shunting: Eisonmenger’s, congenital shunt

V/Q Mismatch: PE, Pneumonia, Pneumothorax, Oedema, Bronchiectasis, Fibrosis

34
Q

Examples of Type II Respiratory failure?

A

Lung parenchyma issues: COPD, asthma, fibrosis, OSA

Neuro issues: stroke, head injury, drugs

Neuromuscular: MND, guillan barré

35
Q

Outline the equipment and steps for a surgical chest drain.

A

Equipment:
sterile pack - drapes, swab. Needles, scalpel. curved clamps, suture kit. Local anaesthetic. chest drain, tubing and drainage.

Procedure:

  1. Mark: based on CXR or 5th IC space
  2. prep and drape clavicle to pelvis
  3. Local: anaesthetic lidocaine layer by layer to pleura
  4. Incision and blunt dissection
  5. secure the incision
  6. insert chest drain
  7. connect to underwater drainage and check for bubbling.