BREAST MASS-MALE BREAST CARCINOMA

Question 1

General considerations

of male breast carcinoma

Answer 1

(a) Rare
1) Incidence is only about 1% of all breast cancer
(b) Average age of occurrence is 70
(c) Increased incidence in men with prostate cancer
(d) First degree relatives of men with breast cancer are at high risk
(e) BRCA 2 mutations are common in men with breast cancer
(f) Prognosis is worse in men than women

Question 2

Signs and symptoms of male breast carcinoma

Answer 2

(a) Patient usually presents with a painless lump
1) With or without nipple discharge, retraction, ulceration or erosion
(b) Physical exam
1) Hard, ill defined, nontender mass beneath the nipple or areola
(c) Gynecomastia
1) Current or history of Gynecomastia
(d) Staging is the same as in women

Question 3

Differential diagnosis of male breast carcinoma

Answer 3

(a) Gynecomastia
(b) Metastatic cancer from another primary
(c) Benign tumors are rare

Question 4

Imaging of male breast carcinoma

Answer 4

Mammography and Ultrasound

Question 5

Diagnoses of male breast carcinoma

Answer 5

(a) Biopsy

1) Should be performed on all men with defined breast masses

Question 6

Treatment of male breast carcinoma

Answer 6

(a) All breast masses should be referred to General Surgery for further
evaluation and work up
(b) Modified radical mastectomy
(c) Radiation
(d) Adjuvant systemic therapy
1) Chemotherapy
2) Targeted therapy

Question 7

Prognosis of male breast carcinoma

Answer 7

(a) 5 year survival
1) Node negative disease – 88%
2) Node positive disease – 69%