Breast Lump

Question 1

Risk factors for breast cancer non-modifiable

Answer 1

BRCA 1-lifetime CA risk breast 72% ovarian 39%
BRCA 2 lifetime CA risk breast 69% ovarian 11-17%
Gender
Age: 80%>50, 28%>70
Prior Hx of breast CA
1st degree relative w/breast cancer (risk increases x2)
Unopposed Estrogen (nulliparity, first pregnancy >30, menarch <12, menopause >55y, NOT breastfeeding, >5y of HRT
Hx of benign breast dz

Question 2

Modifiable risk factors for breast cancer

Answer 2

Decreased weight
Increased activity
EtOH 2-3/day increases risk by 43%
Less hormones exposure
Early pregnancy
Breastfeeding