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Breast > Breast Dx > Flashcards

Breast Dx Flashcards

1
Q

Triple assessment > 40

A 
History and exam
Mammogram
FNA +/- core biopsy
On the day results
Have to wait 1 week for biopsy results
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2
Q

FNA

A

Fine needle inserted into area of breast tissue being investigated. Sample of cells taken up by needle to be sent to pathology lab for cytology
LA not needed, quick procedure

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3
Q

Core biopsy

A

Procedure under LA, could be sitting or lying down on back or side.
A hollow needle is inserted into area of breast tissue investigating. A sample of breast tissue is taken up and sent to pathology lab for grading.

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4
Q

What is the sentinel node?

A

Radioactive dye injected into breast. A probe is used to detect the first node to take up radioactive dye. This LN is then removed surgically for and sent to pathology lab.
+ TNM staging
+ reduces num of patients undergoing ANC unnecessarily

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5
Q

Breast Ca Mx

A

Triple assessment
Surgery (lumpectomy, partial or total mastectomy)
Chemo
Radiotherapy
Targeted therapy (HER2 +ve with herceptin)
Hormone therapy (OR+ with tamoxifen, aromatase inhibitor)

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6
Q

Herceptin S.E.

A

CCF and cardiomyopathy

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7
Q

Pre-menopausal OR+

A

Tamoxifen

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8
Q

Post-menopausal OR+

A

Aromatase inhibitor - Anastrozole

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9
Q

HER2

A

Protein on breast cancer cells which stimulates them to grow

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10
Q

Green nipple discharge

A

Mammary duct ectasia
Inflammatory cells collecting near nipple
Tx: abx, NSAIDs and heat packs

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11
Q

Fat necrosis

A

Painless lump

Calcification on mammogram

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12
Q

Fibroadenoma

A

Benign lump

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13
Q

Paget’s disease of nipple

A

DCIS spread to skin

Gives the appearance of eczema of nipple

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14
Q

Peau d’orange

A

Inflamed breast due to blocked drainage

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15
Q

Triple assessment

A

History & exam
US
FNA +/- core biopsy

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16
Q

Lump ddx

A 
Benign:
Fibroadenoma
Fibrocystic changes
Fat necrosis - green nipple discharge
Abscess - hot, tender, raised CRP
Lipoma
Malignant:
DCIS
Intraductal papilloma - bloody discharge
Paget's disease - invasive ductal carcinoma with nipple involvement
17
Q

Risk factors

A 
COCP
FH
Early menarche
Late menopause
Increasing age
18
Q

Blood discharge from nipple

A

Intraductal papilloma

Breast cancer

19
Q

Screening programme

A

50-70 y/o

Every 3 years

20
Q

Blood tests

A

CA15

BRCA1/BRCA2

Breast (1 decks)

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