Breast Cancer Flashcards

1
Q

Local Symptoms of Breast Cancer

A
  • breast pain
  • breast enlargement
  • nipple retraction
  • nipple discharge
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2
Q

Abnormal Screening on Mammogram

A
  • calcifications
  • architectural distortion’s
  • Frank masses
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3
Q

Local Therapy for Breast Cancer

A
  • removal of tumor
  • evaluation of the axillary lymph nodes
  • radiation therapy
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4
Q

Mastectomy

A

Removal of all breast tissue

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5
Q

Lumpectomy

A

Removal of tumor with a wide margin of normal tissue followed by radiation

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6
Q

Whole Breast Radiation

A

Given five times per week for 5 to 6 weeks

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7
Q

Adjuvant Treatment

A

Treatment that occurs after the surgical removal of cancer. Aimed at preventing reoccurrence of the disease.

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8
Q

Adjuvant Treatment Types

A
  • Radiation
  • Systemic Treatments
    - hormonal therapy
    - chemotherapy
    - targeted biologic therapy
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9
Q

Systemic treatment is based on characteristics of the tumor including?

A
  • size
  • Grade
  • presence or absence of lymph involvement
  • expression of certain receptors
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10
Q

Hormonally directed medications for breast cancer

A
  • Tamoxifen

- Aromatase Inhibitors

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11
Q

Aromatase Inhibitor’s

A
  • Anastrozole (Arimidex)
  • Letrozole (Femara)
  • Exemestane (Aromasin)
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12
Q

HER2/neu

A
  • A protein that is associated with a more aggressive subtype of breast cancer.
  • 20 to 30% of breast tumors express this protein.
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13
Q

Breast Cancer

A

Detected either by abnormal screening mammogram or a lump palpated by patient or physician

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