Breast Cancer

Question 1

When is breast cancer risk reduction therapy usually considered, provided a patient has a >10 year life expectancy?

Answer 1

1. A PMHx of LCIS. 2. Atypical hyperplasia 3. An elevated risk of breast cancer per validated risk estimation models 4. A lifetime risk of >20% based on family-history-based risk model 5. A family history suggesting genetic predisposition 6. A known genetic predisposition 7. Prior thoracic radiation therapy before age 30