Breast CA & Lymphedema Flashcards

1
Q

Cancer Warning Signs

A

C: Changes in bowel & bladder
A: a sore that does not heal
U: unusual bleeding or discharge
T: thickening of lump in breast or elsewhere
I: Indigestion or difficulty in swallowing
O: obvious change in wart/mole
N: nagging cough or hoarseness

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2
Q

Signs of Breast CA

A

New lump or mass, breast swelling, skin irritation or dimpling, breast or nipple pain,nipple retraction, redness/scaliness/thickening of nipple or skin, nipple discharge

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3
Q

Sentinal Lymph Node Biopsy

A

Preferred to axillary lymph node dissection; indicated for ductal carcinoma in situ; radioactive dye is injected in breast (subareolar, peritumoral, intradermal or intraparenchymal); 1-3 nodes are dissected and tested for mets.

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4
Q

Axillary lymph node dissection (ALND) Procedure

A
used to be the standard; 
Level 1 (lat to pec minor) and 2 (beneath pec minor) extraction; level 3 (medial to pec minor) only removed if suspicious.
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5
Q

ALND Risks

A

Long thoracic nerve (winged scapula 2/2 serratus anterior), Thoracodorsal nerve (disrupts brachial IR and ABD above 90 deg), medial and lateral pectoral nerves, Intercostobrachial nerves (numbness of inner arm);

Also–brachial plexus injury, nerve damage and lymphedema, cutaneous numbness, pain, infection, seroma, axillary webbing

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6
Q

Lumpectomy

A

Tumor removal with 1 cm margin for stage 1 & 2 breast invasive carcinoma (Contraindicated in radiation has occurred). Can be guided by palpation, wire, radioactive seed. 2 mm or greater is successful.

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7
Q

Mastectomy Indications

A

Radical procedure, performed if large or multifocal tumor, local recurrence after tx;

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8
Q

Mastectomy Complications

A

Lymphedema, reoccurrance, infection, skin-flap necrosis, “dog-ears,” Seroma, Hematoma, Fibrosis

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9
Q

Modified radical mastectomy

A

breast tissue + pec fascia + ALND

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10
Q

Skin-sparing mastectomy and nipple-sparing mastecotmy

A

presearve breast skin and outline of the inframammary fold; allows for immediate reconstruction;

Candidates: prophylactic mastectomy, early stage breast CA

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11
Q

Extended radical (Halstead) mastectomy

A

only proposed for a tumor that involved pec major; breast tissue, pec major and ANLD and internal mammary lymph node dissection

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12
Q

Contralateral Prophylactic Mastectomy

A

contraversial; risk is only 3-7%; should not be done if pt has locally advanced breast CA

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13
Q

Types of Implants

A

Inflatable with silicone envelope and valve for saline filling; gell-filled with set volume & shape; expanders

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14
Q

Complications of Implants

A

Capsular contracture, implant loss, glandular defects, scar retractions, nipple areola complex (NAC) dislocation

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15
Q

Capsular Contracture

A

(6-12 mo delay, fibroblastic capsule around implant, increases after radiotherapy; sx if severe for surgical capsulotomy; polyurethane coating and textured envelopes help to avoid contracture

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16
Q

Latissimus Dorsi Flap (LDF)

A

Indication: Pec mm affected by radiation and can’t be used to secure implant; Lat is excised and rotated below axilla to fix the implant; Tissue from abdomen is harvested to recontruct breast tissue

(+) safe blood supply, surgical time and rehab short
(-) Back scar, lat tendon cut to avoid bulge, shoulder function

17
Q

Transverse Rectus Abdominus Flap (TRAM)

A

Indication: sufficient tissue of lower abdomen; tissue taken from under umbilicus with resection. blood from sup epigastric.
(+) autologous, natural shape, decreased need for contralateral re-shaping;tummy tuck
(-) surgical time 4-5 hrs, recovery 6-8 weeks (6 days in hospital), mesh required to reinforce abdominal wall, decreased abdominal strength

18
Q

“Free Flaps” aka Microsurgical techniques

A

transfers tissue from abdominal, inner thigh or gluteal areas to create breast

19
Q

Free TRAM technique

A

small portion of rectus around umbilicus is harvested where inf epigastric is located; flap taken to chest wall and anastomosed with thoracodorsal vessel;
(+) improves blood supply, decreased abdominal mm loss, infepigastric better than superior for harvesting; preferred with pts who have had radiation.
(-) flap failure

20
Q

DIEP flap; aka perforator flap

A

skin island by deep inferior epigastric perforator vessel is harvested; preferred to TRAM but must be large enough mm; RA is spared but risk of vascular thrombosis and loss of flap

21
Q

SIEA: Superior Inferior Epigastric Artery flap

A

blood supply harvested from abdominal fatty tissue; spares mm, preferred to DIEP, decreased post op time. Difficult to find an SIEA with enough blood flow

22
Q

Gluteal Artery perforator flap

A

skin and fat harvested within pantyline; indicated for thin women with inadequate abdominal adipose; no loss of tissue, no functional loss, concealed scar

23
Q

gracilis flap

A

gracilis harvested to create B-cup if not enough adipose on abdomen or back; Commonly harvested with reported minimal consequence

24
Q

Microsurgical Breast Reconstruction Recovery

A

6-8 hrs of surgery with anesthesia
3 weeks no driving
8 weeks no lifting> 5 lbs

25
PT after expanders & final implant
2 weeks post-op: limited ROM 2+ weeks: progress to normal activity with ROM Final implant: limited ROM x 1 week; progress after to full ROM
26
PT after Flap Procedures (LDF, TRAM, Microsurgery)
LDF: Week 2-3: Drans intact and overuse of arms contraindicated 2/2 seroma TRAM: no heavy lifting; At 8 weeks begin STM, stretching, MFR--common to feel tight and stiff; may have abdominal pain up to 2 years post-op Microsurgery: No pressure on operative side for 2 mo! Avoid prone or SL on side of repair; No garments or bras.
27
Cellulitis (signs, sxs, tx)
S/s: Rubor, warmth, tenderness, flu-like sxs, fever, swollen lymph nodes; Dx by placing pt in supine and seeing if it resolves (may be disrupted lymphatics post-op) Tx: mild with antibiotics orally, severe with parenteral antibiotics
28
Flap Necrosis
death of surgically excised mm, fat, skin 2/2 poor blood supply; will require office debridement or surgical excision
29
Dehiscence
split in incision line which results in open surgical wound
30
Seroma
pocket of serous fluid at surgical site (usually near axilla); prevent with closed suction drains. Small seroma is advantageous and reduces risk of breast concavity May require decompression
31
Pneumothorax
accumulated air in pleural space/collapsed lung; s/s: SOB, crepitus Cause: excision via wire localization of lesion, deep dissection of the intercostals region Tx: reinflation of lung with chest tube or aspiration with catheter
32
Brachial Plexopathy
damage to brachial plexus S/s: altered sensation, decreased strength and ROM in arm and hand; differentially dx intercostal brachial nerve injury--caused by poor positioning during operation; early intervention helps
33
Axillary web syndrome
formation of taught cords in axilla extending from chest wall to UE--wrist Cause: ALND and SLND; common 2/2 lymphatic and venous disruption in axillary region; S/s: pain with insious onset, decreased ROM in flexion and abduction Tx: Early intervention, antiinflammatories
34
Risk factors for Lymphedema
Axillary dissection, Mastectomy, Radiation of breast/chest wall & nodes Maybe higher BMI, AA, increased age, lower UE function, sedentary behavior
35
Precautions for exercise while patient is undergoing Chemo or radiation
Goal to maintain PA; decrease intensity and duration; Anemia: delay exercise Severe fatigue: 10 min light exercise daily Radiation: avoid Chlorine Osteoporosis: avoid trunk flexion PN: stationary bike over treadmill Avoid gyms and public pools 2/2 decreased immune function
36
Types of Lymphedema
Acute: less than 5 mo: 60% Chronic/Progressive: 30-40% Fluctuating: 15-22% ** Mild are 3x more likely to have mod-sev
37
Objective Measures of Lymphedema
Bioimpedance spectroscopy: observes presence of extracellular fluid water displacement perometry circumferential measures circumferential measures converted to volume measures
38
Surgical tx of Lymphedema
Debaulking procedures, microsurgery, lymphatic-venous anastomosis; * Consider when conservative tx has failed, chronic & pitting; need for compression garments will continue after tx.
39
Medications for lymphedema
Benzopyrones Selenium compounds pentoxifylline (imprved blood flow in vessels) Vit E (skin care)