Breast Flashcards

1
Q

What does a breast triple assessment consist of?

A

History taking + examination, imaging and histology

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2
Q

Decribe a breast examination

A
  • Inspection
    • Symmetry, scars, masses, skin changes (erythema, puckering), nipple changes
    • With hand by side, on hips and behind head
  • Palpation
    • Lumps - position, size, shape, consistency, overlying skin changes, mobility
    • Axilla - lymphadenopathy
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3
Q

What risk factors should be asked about when taking a breast history?

A
  • Family history (first degree relative)
  • Age at menarche
  • Age at menopause
  • How many children?
  • Breastfeeding?
  • At what age did they have their first child?
  • Hormonal birth control or hormone replacement therapy?
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4
Q

What is the mainstay of imaging investigations used for triple assessment?

A

*

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5
Q

What does mammography involve?

A

Compression views of the breast across two views (oblique and craniocaudal), allowing for the detection mass lesions or microcalcifications.

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6
Q

What is ultrasound scanning used for?

A

Ultrasound scanning is more useful in women <35 years and in men, due to the density of the breast tissue in identifying anomalies.

This form of imaging is also routinely used during core biopsies.

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7
Q

A biopsy is required of any suspicious mass or lesion presenting to the clinic, how is this most commonly obtained?

What is the advantage of this compared to fine needle aspiration?

A

Core biopsy

A core biopsy provides full histology (FNA only provides cytology), allowing differentiation between invasive and in-situ carcinoma.

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8
Q

What is mastitis?

What is the most common cause?

A

Mastitis describes inflammation of the breast tissue, both acute or chronic.

By far the most common cause is from infection, typically through S. Aureus, but can occasionally be granulomatous.

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9
Q

How can mastitis be classed?

A
  • Lactational mastitis (more common) is seen in up to a third of breastfeeding women; it usually presents during the first 3 months of breastfeeding or during weaning

It is associated with cracked nipples and milk stasis (often caused by poor feeding technique), and is more common with the first child

  • Non-lactational mastitis (less common) can also occur, especially in women with other conditions such as duct ectasia, as a peri-ductal mastitis

Tobacco smoking is an important risk factor, causing damage to the sub-areolar duct walls and predisposing to bacterial infection

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10
Q

Clinical features of mastitis

A

Tenderness, swelling and erythema over the area of infection

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11
Q

Management of mastitis

A

Antibiotic therapy and simple analgesics

Continue milk drainage or feeding

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12
Q

Types of benign breast tumours

A
  • Fibroadenoma
  • Adenoma
  • Papilloma
  • Lipoma
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13
Q

Fibroadenoma is the most common benign growth in the breast. Who does it usually occur in?

A

Women of reproductive age

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14
Q

Fibroadenoma on examination:

A
  • Highly mobile
  • Well defined and rubbery
  • Most less than 5cm
  • Can be multiple and bilateral
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15
Q

Carcinomas in situ are malignancies that are contained within the basement membrane tissue. They are seen as pre-malignant condition, typically found on imaging and are rarely symptomatic at presentation.

What are the two main types of carcinoma in situ?

A

Ductal Carcinoma In Situ(DCIS) and Lobular Carcinoma In Situ (LCIS)

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16
Q

How is DCIS usually detected?

A

DCIS is often detected during screening, where it appears as microcalcifications on mammography, either localised or wide spread. This will then be confirmed on biopsy.

17
Q

Management of DCIS

A

Any detected localised DCIS should be treated with complete wide excision, ensuring the surrounding tissue of all margins have no residual disease.

Cases of widespread or multifocal DCIS normally requires complete mastectomy.

18
Q

How is LCIS usually diagnosed?

A

LCIS is usually asymptomatic, much like DCIS, however LCIS is not associated with microcalcifications but instead usually diagnosed as an incidental finding during biopsy of the breast.

19
Q

Management of LCIS

A

Dependent of extent of the disease. Low grade LCIS is usually treated by monitoring rather than excision.

20
Q

Invasive carcinoma of the breast can be classified into:

A
  • Invasive ductal carcinoma (75-85%)
  • Invasive lobular carcinoma (10%)
  • Other subtypes (5%), such as medullary carcinoma or colloid carcinoma
21
Q

Which staging system is used for primary breast cancer prognosis?

A

Nottingham Prognostic Index

(Size x 0.2) + Nodal Status + Grade

22
Q

At what age and how often does the NHS breast cancer screening programme invite women for screening?

A

Women aged 50-70yrs to have a mammogram every three years