Breast Flashcards

0
Q

Sentinel node biopsy procedure?

A
  1. Technician sulfur colloid (search for it with gamma probe)
  2. Isosulfan blue (look for blue lymphatics)
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1
Q

Ways to sample lesion for biopsy?

A
  1. Needle localized biopsy

2. Stereotactic core biopsy (costs less, looks better, shorter recovery time)

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2
Q

Axilla – level I versus level II versus level III nodes?

A

Lateral versus under versus medial to pectoralis minor

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3
Q

Postmenopausal breast cancer – post-op management?

A
  1. If estrogen receptor positive, give aromatase inhibitor

2. If cancer larger than 1 cm, give chemo

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4
Q

Adjuvant chemotherapy for premenopausal breast cancer? Post menopausal?

A

Multiagent chemo

  1. CMF (cyclophosphamide, methotrexate, five-FU)
  2. AC – doxorubicin (adriamycin) and cyclophosphamide

If postmenopausal – Multiagent chemo if node positive but not absolutely necessary if node negative

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5
Q

Sporadic versus familial versus hereditary breast cancer?

A

No relatives within two generations

versus

one or more first/second degree relatives versus

Familial but at younger age, bilateral, associated with other primary tumors, autosomal dominant

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6
Q

Differential for bloody nipple discharge?

A
  1. Intraductal papilloma
  2. Paget’s disease of the nipple
  3. Fibercystic change
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7
Q

Galactogram?

A

Cannulation of the affected duct and injection of contrast medium

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8
Q

Bacteria associated with mastitis in non-breast-feeding postmenopausal women?

Differential? Work up?

A

Gram-negative anaerobes

Inflammatory carcinoma.

  1. Immediate breast ultrasound to look for abscess
  2. If No abscess, mammogram
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9
Q

Most aggressive form of breast cancer? Characteristics? Treatment?

A

Inflammatory cancer of the breast

  1. Dimpling of the skin and erythema resembling skin of an orange
  2. Wildly infiltrating with no palpable masses
  3. Invasion of dermal lymphatics (can get skin biopsy)

Multiagent chemotherapy followed by radiation and surgery

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