Breast Flashcards
What is the a/b ratio of the breast
3 Gy
What are the indications for a boost?
<50 or high risk features
E.g. G3
TNBC
N1
Threatened or positive margin
What is the fractionation for whole breast RT post BCS?
26Gy in 5#
What is the increased risk of breast boost?
Double risk of moderate-severe fibrosis
What is the increased risk of breast boost?
Double risk of moderate-severe fibrosis
In what women can post-BCS RT consider being omitted?
> 70
G1-2
T1N0 (<2cm)
ER+ HER2-
Having 5 years ET with mammograms to 10 years
What is the fractionation for chest wall RT?
26Gy in 5#
What is the fractionation for axillary nodal RT?
40Gy in 15#
Assuming an a/b of 3Gy, what is the BED of 26Gy in 5# compared with 40Gy in 15#
40Gy in 15# = 66.7Gy
26Gy in 5# = 60Gy
What are the indications for IMC RT?
- T4 and/or N2/3 disease
- 1-3 macromets (N1) and medial disease
How should IMC RT be delivered
Breath hold
What are the constraints for heart, ipailateral lung, contralateral breast?
Heart V17Gy <10%
Ipsi lung V17Gy <35%
Mean contralateral breast <3.5Gy
In patients who have not received NACT, how should isolated tumour cells and/or micromets only on SLNB be managed?
No axillary treatment needed for micromets only
How should the axillary be managed in patients who have undergone NACT and were thought to be N0 to start with but are found to have fibrosis in 1/3 LN?
No axillary treatment needed (as only 1 with evidence of downstaging in a sample of at least 2 SLNs)
How should the axillary be managed in patients who have undergone NACT and were thought to be N0 to start with but are found to have fibrosis in 1/2 LN?
No axillary treatment needed