Breast Flashcards
Oestrogen receptor women (ER +VE)?
Premenopausal women = Tamoxifen
Postmenopausal women = aromatase inhibitor (ole / ane)
HER2 +VE women should be offered?
Trastuzumab (Herceptin) a monoclonal antibody = Disrupts Her2 receptor.
Name of the ligament that attaches breast lumps to the skin?
Suspensory ligament of copper connects the skin.
Breast abscess management?
Co-amoxiclav + review by the specialist breast team.
What is breast abscess?
an acute (usually bacterial) infection of the breast tissue. Assoc. w/ fever pus discharge from the nipple + local erythema, tenderness and heat.
What is used to screen women between 50 - 70 yrs in UK?
Mammogram
Offered screen every 3 years.
Women who are more likely to acquire breast abscess?
Diabetic women
Breastfeeding women
Benign
Affects sub-areolar ducts
Causes pain + assoc. w/ SMOKERS. Nipple discharge = blood stained.
Mammary Duct Ectasia
management of Mammary Duct Ectasia?
Treat conservatively + settles spontaneously.
What is Paget’s Disease?
Looks like eczema of the nipple/areolar.
Erythematous scaly/rash
indicates breast cancer involving the nipple.
Clinical feature suggesting breast cancer?
Lumps that are hard, irregular, painless / fixed in place
lumps tethered to the skin / chest wall
nipple retraction
skin dimpling / oedema (peau d’organge)
Recommend a two week wait referral for suspected breast cancer for:
Unexplained breast lump in >30s.
unilateral nipple change in >50yrs (discharge, retraction or other changes).
Are Fibroadenoma benign?
Yes. Tumours of stromal/epithelial breast duct tissue
Painless, Smooth, mobile mass, well circumscribed ?
Fibroadenomas
A benign condition triggered by localised trauma, radiotherapy/surgery w/ inflammatory reaction?
Fat necrosis
