Brand/Generic?/Treats?/Testing?/Give if positive? Flashcards

1
Q

Ziagen

A

Abacavir/HIV/HLA-B5701/Y

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2
Q

Plavix - 3/1

A

Clopidogrel/ACS, PAD, Stroke/CYP2C19/D

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3
Q

Tegretol

A

Carbamazepine/Seizures/HLA-B*1502 if of asian ancestry/D

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4
Q

Herceptin 2/1

A

Trastuzumab/Breast and gastric Ca/Her2-neu oncogene/Y

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5
Q

Kadcyla

A

Ado-Trastuzumab, Emtansine/breast and gastric Ca/ Her2-neu oncogene/Y

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6
Q

Erbitux - 2/2

A

Cetuximab/Colorectal Ca, NSCL Ca/K-Ras mutation, EGFR/N, Y

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7
Q

Vectibix

A

panitumumab/Colorectal Ca/K-Ras mutation/N

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8
Q

Tarceva

A

erlotinib/NSCL Ca/EFGR/Y

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9
Q

Gleevec 2/1

A

Imatinib/GIST, CML/cKIT, BCR-ABL/Y

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10
Q

Selzentry

A

Maraviroc/HIV/Tropism for CCR5/Y

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11
Q

Sprycel

A

dasatinib/CML/BCR-ABL/Y

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12
Q

Tasigna

A

nilotinib/CML/BCR-ABL/Y

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13
Q

Bosulif

A

nosutinib/CML/BCR-ABL/Y

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14
Q

Arzerra 3/1

A

ofatumumab/NHL, HL, CLL/CD-20/Y

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15
Q

Rituxan

A

Rituximab/NHL, HL, CLL/CD-20/Y

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16
Q

Olysio

A

Simeprevir/Hep C/NS3 Q80K/N

17
Q

Xalkori

A

Crizotinib/Metastatic NSCLC/Anaplastic lymphoma kinase (ALK)/Y

18
Q

Zelboraf

A

Vemurafenib/Metastatic melanoma/BRAF V600E mutation/Y

19
Q

Bexxar

A

Tositumomab/NHL /MS4A1/Y

20
Q

Adcetris 2/1

A

Brentuximab Vedotin/HL, Systemic anapestic large cell lymphoma/TNFRSF8/Y

21
Q

Ontak

A

Denileukin Diftitox/Cutaneous T-cell lymphoma/IL2RA (CD-25)/Y

22
Q

Kalydeco

A

Ivacaftor/CFTR/CFTR G551D/Y

23
Q

Zyloprim

A

Allopurinol/Gout/HLA-B*5801/-

24
Q

Jantoven 1/2

A

warfarin/clot prevention/CYP2C9, VKORC1/D

25
Q

Dilantin

A

phenytoin/Seizure/HLA-B*1502/N