Brand/Generic Flashcards
Acetaminophen (Oral)
Tylenol
Acetaminophen ( Rectal Suppository)
FeverAll
Acetaminophen (IV Injection)
Ofirmev
Hydrocodone + Acetaminophen (4 names)
Norco, Lorcet, Lortab, Vicodin
Acetaminophen + Oxycodone (2 names)
Percocet, Endocet
Acetaminophen + Codeine
Tylenol #3, #4
Aspirin + Caffeine
Excedrin Tension Headache
Acetaminophen + aspirin + caffeine
Excedrin Extra Strength, Excedrin Migraine
Acetaminophen + caffeine + pyrilamine
Midol Complete
Ibuprofen (3 names)
Advil, Motrin IB, Caldolor
Dyspepsia, abdominal pain, nausea limit self treatment to 10 days
Indomethacin
Indocin
CNS side effects
Naproxen
Aleve
Dosed BID
Naproxen + Esomeprazole
Vimovo
Naproxen + Sumatriptan
Treximet
Ketorolac
Toradol
Max 5 day duration (any formulation)
Acute renal and liver failure
Nasal spray must be primed 5x before use
Celecoxib
Celebrex
Avoid in sulfonamide allergy
Has the highest COX-2 selectivity
Diclofenac
Voltaren
Total body max dose of 32 g/day
Avoid misoprostol combo (Arthrotec) in women of childbearing potential
Meloxicam
Mobic
Aspirin EC (3 names)
Ascriptin, Bufferin, Ecotrin
Overdose can cause tinnitis
Avoid in children with viral infections
Take 1 hr before or 8 hr after ibuprofen
Aspirin ER capsule
Durlaza
Overdose can cause tinnitis
Avoid in children with viral infections
Take 1 hr before or 8 hr after ibuprofen
Magnesium Salicylate
Doan’s Extra Strength
Codeine
Prodrug converted to morphine via CYP2D6
Do not use in children under 12 (or under 18 if tonsillectomy/adenoidectomy)
Fentanyl (2 names)
Duragesic, Sublimaze
1 patch every 48-72 hrs
Do not use on opioid naive patients unless they use morphine 60 mg/day equivalent for a week
CYP3A4 SUBSTRATE
Hydrocodone IR/ER (no brand)
CYP3A4 SUBSTRATE
Hydromorphone
Dilaudid
Potent, high overdose risk
Methadone (2 names)
Dolophine, Methadose
CYP3A4 SUBSTRATE
QT prolongation
Variable half life
Can decrease testosterone level
Try to avoid with MAOIs
Meperidine
Demerol
Renal impairment and CNS toxicity for elderly
SEROTONERGIC AGENT
Morphine ER
MS Contin
Pruritis (can be treated with Benadryl)
Morphine Injection
Duramorph, Infumorph
Pruritis (can be treated with Benadryl)
Oxycodone IR
Roxicodone
CYP3A4 SUBSTRATE
Pruritis (can be treated with Benadryl)
Oxycodone CR
OxyContin
CYP3A4 SUBSTRATE
Pruritis (can be treated with Benadryl)
Oxymorphone (no brand)
Take on empty stomach
Methylnaltrexone
Relistor
PAMORA
Only for use after failing OTC laxatives
Can cause GI perforation
Naloxegol
Movantik
PAMORA
Can cause GI perforation
Naldemedine (no brand)
PAMORA
Can cause GI perforation
Tramadol
Ultram
CYP3A4 and 2D6 SUBSTRATE
SEROTONERGIC
SEIZURE RISK
Do not use in children under 12 (or under 18 if tonsillectomy/adenoidectomy)
Tapentadol is C-II, Tramadol is C-IV
Naloxone
Narcan
Older drug: Nalmefene
Buprenorphine (4 names)
Belbuca (buccal film)
Butrans (patch)
+ Naloxone = Suboxone (SL film)
+ Naloxone = Zubsolv (SL tablet)
C-III
QT Prolongation
Gabapentin
Neurontin
Dizziness, somnolence, peripheral edema, weight gain
Pregabalin
Lyrica
Carbamazepine
Tegretol
Approved for trigeminal neuralgia
Baclofen
Lioresal
Cyclobenzaprine (2 names)
Amrix, Fexmid
Serotonergic
Tizanidine
Zanaflex
Can cause hypotension
Carisoprodol
Soma
C-IV
CYP2C19 substrate
SEDATION
Methocarbamol
Robaxin
SEDATION
Rizatriptan
Maxalt-MLT
Tablet and ODT
Only Triptan approved for ages 6+
Sumatriptan
Imitrex: Nasal spray, SC injection
Imitrex STATdose: SC autoinjector
Zembrace SymTouch: SC autoinjector
Onzentra Xsail: Nasal powder
DO NOT PRIME THE NASAL SPRAY
ORAL, SPRAY, POWDER: CAN REPEAT DOSE AFTER 2 HRS
SUBQ: CAN REPEAT DOSE AFTER 1 HR
Zolmitriptan
Zomig ZMT
ODT, tablet, nasal spray
Triptans approved for age 12+
Almotriptran, Zolmitriptan NS
ALL TRIPANS SHOULD NOT BE USED IN HEART DISEASE
Dihydroergotamine (2 names)
D.H.E. 45, Migranal
CYP3A4 SUBSTRATE
IM,SC,IV,NS
Prime nasal spray with 4 pumps
SHOULD NOT BE USED IN HEART DISEASE
Rimegepant (no brand)
Calcitonin Gene Related Peptide (CGRT)
CYP3A4 SUBSTRATE
Used for prevention AND treatment
ODT
Ubrogepant
Calcitonin Gene Related Peptide (CGRT)
CYP3A4 SUBSTRATE
Used ONLY for prevention
Lasmiditan
C-V
May cause bradycardia and CNS depression (avoid driving)
5-hT1F agonist
DOES NOT CAUSE VASOCONSTRICTION
Other migraine treatments
Atogepant (tablet)
Eptinezumab-jjmr (IV q3 months)
Erenumab-aooe (SC q month)
Frenabezumab-vfrm (SC q month or q3 months)
Galcanezumab-gnlm (SC q month)
Colchicine
Colcrys
P-gp and CYP3A4 substrate
Start within 36 hours of symptom onset
Can cause myelosuppression
Two 0.6 mg tablets followed by 0.6 mg 1 hr later (total 1.8 mg)
Allopurinol (2 names)
Zyloprim, Aloprim
Severe rash (SJS) and hepatotoxicity
Test for HLA-B*5801, do not use if +
Use with colchicine or NSAIDS for 3-6 months
Febuxostat (no brand)
Only use if unable to tolerate allopurinol
Lesinurad (no brand)
Can cause acute renal failure
Inhibits reabsorption of uric acid in kidneys
Probenecid (no brand)
Can be used to increase beta lactam levels in body
Inhibits reabsorption of uric acid in kidneys
Pegloticase (no brand)
Converts uric acid to allantoin
Premedicate with antihistamine and steroids
G6PD deficiency can not use
Do NOT use with allopurinol, febuxostat, probenecid
INJECTION