Branching Morphogenesis Flashcards

1
Q

name of descriptive models of branching behaviour

A

L-systems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Give example for an L-system for regular placement (of heterocysts in Anabena)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Give example for an L-system for btanching structure

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the turtle interpretation of the branching L-system

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The three rules of branching behaviour?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is subtree persistence?

A

Length of subtrees higher than certain threshold gen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe a general mechanistic model for branching?

A

Diffusion Limited Aggregation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How can DLA be implemented using CA?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why CA branches formed from two initial seeds will never touch?

A

between the two seeds a depletion zone will occur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

where do branches grow the fastest?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe how a branching model can be used for studying lung tissue branching

A

Growth of tissue cells is modelled as pressure gradient pushing the tissue outward in response to FGF concentration gradient leading to growth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe on this phase diagram of lung tissue branching growth what are the two axes?

A

y: Diffusion and x: concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How can a DLA model be extended to form tissue branches which are smoother, more bio-looking and at lower number as seen in experiments?

A

surface tension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How do the following results relate to the DLA model?

A

Reduction in surface tension leads to more branching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the polyp fanning effect

A

convex surface => more competition and the opposite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does higher polyp density affect branching

A

higher polyp density => finer branching as there are less resources per coral and lower censity=> thicker less expressed branching

17
Q

How does surface tension affect branching in sprouting cells in a CPM?

A
18
Q

What is fractal dimension?

A

N:number of samples
l: scaling factor
D: fractal dimensions