Branching Morphogenesis Flashcards
name of descriptive models of branching behaviour
L-systems
Give example for an L-system for regular placement (of heterocysts in Anabena)
Give example for an L-system for btanching structure
what is the turtle interpretation of the branching L-system
The three rules of branching behaviour?
What is subtree persistence?
Length of subtrees higher than certain threshold gen
Describe a general mechanistic model for branching?
Diffusion Limited Aggregation
How can DLA be implemented using CA?
Why CA branches formed from two initial seeds will never touch?
between the two seeds a depletion zone will occur
where do branches grow the fastest?
Describe how a branching model can be used for studying lung tissue branching
Growth of tissue cells is modelled as pressure gradient pushing the tissue outward in response to FGF concentration gradient leading to growth.
Describe on this phase diagram of lung tissue branching growth what are the two axes?
y: Diffusion and x: concentration
How can a DLA model be extended to form tissue branches which are smoother, more bio-looking and at lower number as seen in experiments?
surface tension
How do the following results relate to the DLA model?
Reduction in surface tension leads to more branching
What is the polyp fanning effect
convex surface => more competition and the opposite
How does surface tension affect branching in sprouting cells in a CPM?
What is fractal dimension?
N:number of samples
l: scaling factor
D: fractal dimensions
