Brain Tumours Flashcards

1
Q

How many brain tumours per year

A

11,000

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2
Q

How are tumours classified

A

Primary (originated in brain) vs secondary (Metastases)

Intratentorial (below tent) vs supratentorial (above tent)

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3
Q

What forms of tumour are more common in children

A

Medullablatomas
Astrocytoma
(Infratentorial)

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4
Q

What tumours are more common in adults

A

Meningiomas
Metastaces
Gliomas
(Supratentorial)

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5
Q

What are some symptoms of brain tumours

A

Intracranial pressure headaches which are worse in the morning and cause nausea

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6
Q

How many people admitted with a headache have a tumour

A

<0.1%

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7
Q

What are two different types of seizure

A

Localised- one area eg arm

Generalised- effects whole body

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8
Q

What must brain tumours be differentially diagnosed from

A

Trauma (haematoma)
Infections (HIV which can cause swelling )
Vascular (aneurysm)
Inflammatory (MS)

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9
Q

Discuss metastasis that form brain tumours

A

Lung metastasis form 33% of brain tumours
Breast metastasis form 20% of brain tumours
66% of skin cancers (melanomas) spread to brain

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10
Q

What are the most common forms of primary tumours in the brain

A

Gliomas - 40-50%
Meningiomas -15-20%
Pituitary tumours -10%

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11
Q

Discuss glioblastomas and their life expectancies

A
Full name- Glioblastoma Multiforme
Very aggressive 
Low grade- stage 1- 8/10 years 
Stage 2- 5> years 
High grade- stage 3 -2/5 years
Stage 4 - 3/7 months
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12
Q

Discuss meningiomas

A

Occur in brain coverings
Form 20% of primary brain tumours
Usually a good outcome

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13
Q

What is the status called which assessed how much a tumour effects your everyday life

A

Karnofsky performance status

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14
Q

Discuss the initial management and surgery options for brain tumours

A

Initial management- reduce swelling (dexamethasone)
Treat seizures (anti epileptic drugs)
Blood tests

Surgery 
Debulk 
Complete excision 
Image guidance 
Awake craniotomy
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15
Q

How is radiation implimented

A

In a processed called ‘fractioned treatment’ which means completing it over a period of time so it is more bare able for the patient

Stereotactic radio surgery- focus radiation in relevant part of brain

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16
Q

Discuss the forms of chemotherapy

A

Temozolamide - used with high grade gliomas
Brachy implantation- inject chemo itself
Intraventricular - inject into appropriate ventricle