Brain tumors Flashcards

1
Q

S+S SOL

A

ICP - headache, vomiting, papilloedema
Seizures
Focal neurology
Personality changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Temporal lobe SOL

A

Dysphagia
Homonymous hemianopia
Amnesia
Odd phenomenon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Frontal lobe SOL

A

Hemiparesis
Personality change
Broca’s dysphasia
Executive dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Orbitofrontal syndrome SOL

A

Lack of empathy, over-eating, disinhibition

Over familiar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Parietal lobe SOL

A

Hemisensory loss
Dysphagia
Gerstmann’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Occipital lobe SOL

A

Visual field defects
Palinopsia
Polyopia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cerebellum SOL

A
Dysdiadochokinesis
Ataxia
Slurred speech
Hypotonia
Intention tremor
Nystagmus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cerebellopontine angle SOL

A

Ipsilateral deafness
Nystagmus
Facial weakness
6th nerve palsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pathology of schwannoma

A

Benign nerve sheath Schwann cell tumour

Associated with neurofibromatosis 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Complications of schwannoma

A

Becomes malignant

Left untreated can cause brainstem compression, cerebellar tonsil herniation, hydrocephalus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

S+S of schwannoma

A

Cochlear nerve = hearing loss, tinnitus
Vestibular nerve = walking disequilibrium
Trigeminal nerve = facial paraesthesia, pain
Facial nerve = facial paresis, gustatory disturbances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Management of schwannoma

A

Excision

RT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pathology of glioblastoma

A

Highly malignant aggressive glial cell tumor

Usually in hemispheric white matter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

RF for glioblastoma

A

White males
Jews
Li Fraumeni
Tuberous sclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Complications of glioblastoma

A

Extension to ventricular wall
Meningeal gliomatosis
Mass effect
Seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

S+S of glioblastoma

A

Severe morning headache

Mental changes - altered mood, personality, impaired concentration

17
Q

Management of glioblastoma

A

Avastin
Surgery
Adjuvant chemo + RT

18
Q

Pathology of hemangioblastoma

A

Benign tumour, vascular cell proliferation

Cherry red cystic mass in cerebellum, spinal cord + brainstem

19
Q

RF for hemangioblastoma

A

Males 20-50

Von Hippel-Lindau

20
Q

Complications of hemangioblastoma

A

Acute hemorrhage
Tumor mass effect
Local structure compression
Paraneoplastic erythrocytosis

21
Q

S+S of hemangioblastoma

A

Brainstem = visual, sensory impairment + motor weakness
Cerebellum = ataxia
Spinal cord = pain, sensory impairment

22
Q

Management of hemangioblastoma

A
Antiangiogenic treatment (reduced EDGF production)
Surgery
23
Q

Pathology of meningioma

A

Tumor arising from meningeal arachnoid cells

Intracranial

24
Q

RF for meningioma

A
Neurofibromatosis 2 
Schwannomatosis 
MEN1
Ionising radiation 
Obesity 
Black
Females 
Older age
25
Q

Complications of meningiomas

A

Mass effect - obstructive hydrocephalus + raised ICP, herniation
Reactive sclerosis, bone invasion
Seizures

26
Q

S+S meningioma

A
Asymptomatic 
Visual impairment 
Impaired hearing 
Behavioural changes 
Muscle weakness
27
Q

Management of meningioma

A

Monitoring
Surgery
RT

28
Q

S+S of oligodendroglioma

A

Asymptomatic
Seizures
One-sided muscle weakness, impaired sensory perception, impaired memory
Impaired language