Brain Tumors Flashcards
Most common primary brain tumors
- Glioblastoma multiforme
- Meningioma
- Schwannoma
Most common primary brain tumor, poor prognosis, in cerebral hemispheres
Glioblastoma multiforme
“Butterfly glioma”
Glioblastoma multiforme
GFAP
Intermediate filament in astrocytes, stains + in glioblastoma multiforme and pilocytic astrocytoma
Pesudopalisading with endothelial cell proliferation
Glioblastoma multiforme
2nd most common primary brain tumor, benign, most often in convexities of hemispheres and parasagittal region, from arachnoid cells, does not invade cortex, can cause seizures, resectable
Meningioma
Whorled pattern with psammoma bodies
Meningioma
Psammoma bodies
Laminated calcifications
CN that Schwannomas localized to
CNVIII
3rd most common primary brain tumor, found at cerebellopontine angle, +S-100
Schwannoma
B/L Schwannomas seen in what condition
Neurofibromatosis type 2
Slow-growing tumor in frontal lobes, chicken-wire capillary pattern, “fried egg” cells, can present with seizures, white matter
Oligodendroglioma
Most commonly a prolactinoma, bitemporal hemianopsia
Pituitary adenoma
Well-circumscribed tumor in children, GFAP+, benign, often cerebellar
Pilocytic astrocytoma
Rosenthal fibers, cystic lesion with mural nodule
Pilocytic astrocytoma
Highly malignant cerebellar tumor, PNET, can cause compress 4th ventricle –> hydrocephalus
Medulloblastoma
Tumor that undergoes “drop metastasis”
Medulloblastoma
H-W rosettes
Medulloblastoma
Malignant tumor, commonly found in 4th ventricle, poor prognosis
Ependymoma
Perivascular peseudorosettes
Ependymoma
Often cerebellar, associated with with von Hippel-Lindau sd. when seen with retinal angiomas
Hemangioblastoma
Foamy cells and high vascularity
Hemangioblastoma
Benign childhood tumor, bitemporal hemianopsia, reoccuring, calcification
Craniopharyngioma
Derived from remnants of Rathke’s pouch
Craniopharyngiom
