Brain stem and cranial nerves Flashcards

1
Q

What are the major parts of the brainstem?

A

Midbrain - divided into dorsal tectum and ventral tegmentum
Pons - lies between medulla and the midbrain
Medulla oblongata - conical continuation of the spinal cord within the skull, beginning at the foramen magnum. It’s limited above by the caudal border of the pons and the bulbopontine sulcus.

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2
Q

How can the midbrain be divided up?

A

The midbrain can be divided into the tectum and the paired cerebral peduncles. Internally, the cerebral peduncles are further separated by the substania nigra into the crus cerebri (anterior) and the tegmentum (posterior).

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3
Q

What makes up the tectum?

A

The tectum houses four rounded prominences named colliculi (collectively the corpora quadrigemina) which sit directly inferior to the pineal gland. The colliculi are separated by the cruciform sulcus.
Superior colliculi - part of the visual system, concerned with eye reflexes
Inferior colliculi - part of the auditory system, concerned with the reflex of looking towards a loud noise

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4
Q

What are the cerebral peduncles?

A

The paired cerebral peduncles extend from the cerebral hemispheres to converge as they meet the pons. They are separated anteriorly in the midline by the interpeduncular fossa

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5
Q

What are the crus cerebri?

A

The crus cerebri is the anterior portion of the cerebral peduncle which contains the motor tracts, travelling from the cerebral cortex to the pons and spine. It contains the following tracts:
Frontopontine fibres – located most medially.
Corticospinal fibres – motor fibres from the primary motor cortex.
Corticobulbar tracts – motor fibres from the primary motor cortex.
Temporopontine fibres – located posterolaterally.

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6
Q

What are the different parts of the substantia nigra?

A

The substantia nigra – a pigmented nucleus that separates the two regions of the cerebral peduncles. It is further broken down into the pars reticulata (anterior) and pars compacta (posterior).

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7
Q

Which nerves can be found in the periaquaductal grey matter?

A

Within the periaqueductal gray matter lies the mesencephalic nucleus of the trigeminal nerve, as well as the trochlear nucleus with its fibres continuing around the gray matter to exit the midbrain.

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8
Q

What is the structure of the pons?

A

It is a group of nerves that function as a connection between the cerebrum and cerebellum.
The anterior or ventral surface of the pons is marked by a bulging formed by the transverse pontocerebellar fibers. The basilar groove demarcates the midline of the ventral surface and is where the basilar artery is located.

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9
Q

What is the pontomedullary junction?

A

The pontomedullary junction is an important anatomical landmark defined by the angle between the lower border of the pons and the superior border of the medulla.

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10
Q

Which cranial nerves come from the pons?

A

CNV, VI, VII, VIII originate from the ventral surface of the pons.

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11
Q

How is the pons connected to the cerebellum?

A

The pons is intimately related to the cerebellum, and is connected to it by the middle cerebellar peduncles. Removal of the cerebellum will reveal the underlying fourth ventricle.

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12
Q

What marks the floor of the fourth ventricle?

A

The medial eminence marks the midline of the floor of the fourth ventricle

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13
Q

What is the facial colliculus?

A

The facial colliculus is a bulge formed by the fibers of the facial nerve looping around the abducens nucleus.

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14
Q

What is the stria medullaris?

A

The stria medullaris of the fourth ventricle is a bundle of nerve fibers crossing transversely from the lateral aspect into the midline. They mark the posterior border between the pons and the medulla.

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15
Q

What is the cerebellopontine junction?

A

The angle formed at the junction of the pons, medulla, and cerebellum is another anatomical landmark and is named cerebellopontine angle.

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16
Q

What are the two major parts of the pons?

A

The ventral pons contains the pontine nuclei, which are responsible for coordinating movement. Fibers from the pontine nuclei cross the midline, and form the middle cerebellar peduncles on their way to the cerebellum.
The tegmentum is the evolutionarily older part of the pons which forms part of the reticular formation – a set of nuclei found throughout the brainstem that are responsible for arousal and attentiveness.

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17
Q

What tracts go through the pons?

A

Descending corticospinal tracts – responsible for voluntary motor control of the body.
Descending corticobulbar tracts – responsible for voluntary motor control of face, head and neck.
Ascending medial lemniscus tracts – responsible for fine touch, vibration and proprioception.
Ascending spinothalamic tracts – responsible for pain and temperature sensation

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18
Q

What is the bulbopontine sulcus?

A

A transverse groove at the caudal border of the Pons

19
Q

What are the borders of the medulla?

A

The superior margin of the medulla is located at the junction between the medulla and pons, while the inferior margin is marked by the origin of the first pair of cervical spinal nerves. This occurs just as the medulla exits the skull through the foramen magnum.

20
Q

What is the anterior median fissure?

A

A partial division of the medulla in the ventral midline

21
Q

What is a pyramid?

A

An elongated eminence (swelling) marking the position of underlying fibres passing from the cerebral hemisphere to the cord, the corticospinal or pyramidal tract

22
Q

What is decussation of the pyramids?

A

Diagonally oriented bundles of fibres crossing the fissure via which about 80% of the corticospinal fibres cross the midline to enter the opposite lateral white column of the spinal cord

23
Q

What is the ventrolateral sulcus?

A

On the lateral border of the pyramid on each side, continuous with the same groove in the spinal cord

24
Q

What is an olive?

A

Lateral to the ventrolateral sulcus, this eminence is cause by the presence of the underlying inferior olivary nucleus and is concerned with the control of movement.

25
Q

What is the inferior cerebellar peduncle?

A

Forms the posterolateral margin of the medulla, a thick bundle of white matter passing into the cerebellum

26
Q

What is the posterior median sulcus of the pons?

A

The posterior surface has a midline structure – the posterior median sulcus – which is continuous below as the posterior median sulcus of the spinal cord.

27
Q

What are the gracile and cuneate tubercles?

A

Gracile tubercle - a round swelling on either side of the midline
Cuneate tubercle - a swelling lateral to the gracile tubercles

The nuclei underlying the gracile and cuneate tubercles are often called the Dorsal Column Nuclei and are a major relay site for the Dorsal Column Sensory Pathway.

28
Q

What are the pyramidal tracts?

A

The motor signals from the precentral gyrus to the rest of the body
85% of motor fibres housed within the pyramids cross diagonally and posteriorly, and continue down the spinal column as the lateral corticospinal tracts (upper limbs and lower limbs)
15% of motor fibres stay on the same side (positional muscles) - these fibres crossover to the opposite side at the level of the muscle
If damaged, there is loss of motor function to the opposite side of the body.

29
Q

What is Bell’s palsy?

A

Acute unilateral inflammation of the facial nerve (lower motor neuron)
Symptoms (unilateral): pain behind the ear, paralysis of facial muscles and failure to close eye
Signs (unilateral): absent corneal reflex, hyperacusis (certain sounds heard unpleasantly loud), loss of taste on anterior two-thirds of tongue
If it’s caused by Herpes Zoster (virus that also causes shingles), a vesicular rash is present in the external auditory canal and on the oropharynx.

30
Q

What is Bulbar palsy?

A

Impairment of the functions of the cranial nerves that arise from the medulla (9, 10, 11, 12).
Symptoms: dysphagia (difficulty swallowing), slurring of speech, dysphonia (difficulty forming sounds), excess saliva (dribbing)
Signs: wasting and fasciculating tongue, absent gag reflex
Causes: motor neuron disease, Guillain-Barre syndrome
Pseudobulbar palsy presents with similar symptoms but the lesion is in the upper motor neurons e.g. caused by stroke or multiple sclerosis

31
Q

What is central pontine myelinolysis?

A

Destruction of myelin in the pons causes confusion, balance problems, dysphagia, hallucination, reduced consciousness, slurred speech, tremor and weakness in the face or limbs.
Occurs when sodium levels are corrected too quickly - care must be taken to increase sodium levels slowly when a patient is hyponatremic.

32
Q

What is the CNI?

A

Olfactory nerve
Special sensory - smell
Leaves skull by cribiform plate

33
Q

What is CNII?

A

Optic nerve
Special sensory - sight
Leaves skull by optic canal

34
Q

What is CNIII?

A

Oculomotor nerve
Motor
4 extrinsic eye muscles and levator palpebrae, pupillary sphincter
Leaves skull by superior orbital fissure

35
Q

What is CNIV?

A

Trochlear nerve
Motor
Superior oblique
Leaves skull by superior orbital fissure

36
Q

What is CNV?

A

Trigeminal nerve
Both sensory and motor
Opthalamic - scalp, forehead and nose (S)
Maxillary - cheeks, lower eye lip, nasal mucosa, upper lip, upper teeth and palate (S)
Mandibular - anterior ⅔ tongue, skin over mandible, skin over the mandible and lower teeth (S)
Muscles of mastication (M)
Leaves by:
Op - Superior orbital fissure
Max - foramen rotundum
Man - Foramen ovale

37
Q

What is CNVI?

A

Abducens nerve
Motor
Lateral rectus
Leaves skull by Superior orbital fissure

38
Q

What is CNVII?

A

Facial nerve
Both sensory and motor nerve
Sensation to external ear, taste from anterior ⅔ tongue, hard and soft palate (S)
Muscles of facial expression, lacrimal, submandibular, sublingual and mucous glands of mouth and nose (M)
Leaves skull by internal acoustic meatus

39
Q

What is CNVIII?

A

Vestibulocochlear nerve
Special sensory - hearing and balance
Leaves skull by internal acoustic meatus

40
Q

What is CNIX?

A
Glossopharyngeal nerve
Both sensory and motor
Posterior ⅓ tongue, external ear, and middle ear cavity.
Carotid body and sinus.
Taste from posterior ⅓ tongue (S)
Parotid gland (M)
Stylopharyngeus (M)
Leaves skull by jugular fissure
41
Q

What is CNX?

A

Vagus nerve
Both sensory and motor
External ear, larynx and pharynx, thoracic and abdominal viscera (S)
Taste from epiglottis region of tongue (S)
Smooth muscles of the larynx and pharynx (M)
Leaves by jugular fissure

42
Q

What is CNXI?

A
Accessory nerve
Motor
Trapezius and sternocleidomastoid
Some fibres to viscera with CNX
Leaves by jugular fissure
43
Q

What is CNXII?

A

Hypoglossal nerve
Motor
Intrinsic and extrinsic muscles of the tongue
Leaves by hypoglossal canal