Brain Cancer Flashcards
Definite risk factors for brain tumour
Neurofibromatosis
Tuberous sclerosis
Immunosuppression
Therapeutic ionising radiation
Most common cancer that metastasise to the brain
Lung (small cell more than nsc)
Breast
Renal cell
Melanoma
Colorectal
What three tumours arise from glial cells
Astrocytoma ( most malignant) - glioblastoma multiforme
Oligodendroglioma
Ependymoma
Where do vestibular neuromas arise
Cerbellopontine angle
Most common type of primary brain tumour
Glioma
What grading system is used in brain tumour
WHO
What grade are meningiomas
1 usually
Bilateral vestibular neuromas are seen in what conditions
Neurofibromatosis 2
Imaging for brain tumour
CT and MRI
MRi is better
Grade the following
Pilocystic astrocytoma
Diffuse astrocytoma
Anaplastic astrocytoma
Glioblastoma multiforme
They are in order of grades
1p19q deletion is diagnostic of what
Oligodendroglioma
What kind of brain tumour is often calcified
Meningioma
What kind of genetic marker shows that a brain tumour is going to respond better to chemotherapy
MGMT methylation
What treats oedema in brain.
Dexamethasone
Neurofibromatosis types 1 and 2 chromosomal abnormality
NF1= c17
NF2 = c22
Both are autosomal dominant
Cafe au lait spots, axilloary freckles and neurofibromas seen in which condition
NF1
