Brain Bee Comp Flashcards

1
Q

What are the 3 ways we learn about neuroscience and what do they mean?

A
  1. Experimental Design (scientists develop a research question and hypothesis and answer them by experimenting)
  2. Observational Study (no separation of patients into groups or any other form of intervention, which can have several confounding variables)
  3. Case Study (a highly detailed description of a certain, abnormal case)
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2
Q

What are some common myths about the brain?

A
  1. We only use 10% of our brain

Truth: We use all of our brains, and most of our brains are active, the majority of the time, just not at the same time
Think: Traffic light

  1. Forming new memories causes new neurons to be formed
    Truth: most likely, memories are stored in the synapses. Also, most cell reproduction is halted for adult neurons (not impossible, but not likely or common)
  2. The brain does not repair itself
    Truth: the brain is plastic, and can, therefore, find ways to rewire itself (not the case for all issues)
  3. If you are analytical, you are left-brain dominant, if you are creative, you are right-brain dominant
    Truth: Almost every function that the left side can do, the right side can also do and vice versa
    The only process that can typically be assigned to the left hemisphere is the processing and production of language → reason unknown
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3
Q

What are the fields involved in neuroscience? (5)

A

Chemistry
Psychology
Biology
Physics
Computational Neuroscience

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4
Q

What does rostral/anterior mean?

A

Front

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5
Q

What does Caudal/Posterior mean?

A

Back

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6
Q

What does Dorsal or Superior mean?

A

Top

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7
Q

What does Ventral/Inferior mean?

A

Bottom

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8
Q

What is the difference between white and gray matter?

A

White:
- White matter generally represents pathways for communication
- For neurons to send signals rapidly, the cells can be modified in a way that adds several layers of fatty lipids called myelin

Gray:
- Gray areas are usually dense with cell bodies

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9
Q

What is it called when a white matter pathway moves from one hemisphere to another?

A

Decussation

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10
Q

What is the Corpus Callosum?

A

The main white matter tract that allows for information to pass between the 2 hemispheres

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11
Q

What are the 3 compartments of the neural tube?

A
  1. Rhombencephalon or hindbrain
    - oldest part of the brain
    - It breaks into 2 parts:

A. Myelencephalon
- Develops into the medulla oblongata
- the medulla oblongata contains many clumps of neurons that are responsible for functions that an organism carries out unconsciously (breathing, heartbeat, etc)
- It also contains areas that detect toxins in the blood that come from dietary sources, triggering vomiting

B. Metencaphalon
- Develops into the pons and cerebrum

Pons
- helps perform involuntary actions (like breathing)
- Contains several areas that help us hear and taste

The cerebrum
- Also known as the little brain
- Enables motor control functions (balance, coordination, posture, etc)

  1. Mesencephalon/Midbrain
    - performs several functions
  2. Prosencephalon/ Forebrain
  • Develops into the “higher order” brain regions, including the cerebral cortex (the outer layer)
  • Contains a few major structures like the hypothalamus and basal ganglia
  • the hypothalamus, also known as the “relay station” because almost every sensory mortality passes through the thalamus
  • the hypothalamus serves as a communication route to the body’s endocrine system (the complex network of hormonal glands)
  • the basal ganglia are made up of a series of brain structures that are used for behaviours such as motor and habit learning, emotional processing, and action selection
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12
Q

What is the difference between a sulcus, gyrus, and fissure?

A

Sulcus: groove
Gyrus: Smooth
Fissure: Deeper groove

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13
Q

What is the main function of the occipital lobe?

A

Processing visual stimuli

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14
Q

What is the main function of the temporal lobe?

A
  • holds the hippocampus, which holds structures important for language
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15
Q

What is the main function of the parietal lobe?

A
  • able to detect things we can touch
    (touch, temperature, vibration)
  • also able to detect where various parts of the body are located
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16
Q

What is the main function of the frontal lobe?

A
  • contains neurons that control the movement of the body
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17
Q

The spinal cord is housed within a series of bones called WHAT?

A

The vertebral column

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18
Q

There are afferent and efferent nerves, branching out from the spinal cord. When they merge, they are called WHAT?

A

Spinal nerves

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19
Q

How many spinal nerves do humans have?

A

31

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20
Q

What are the 4 regions of the spinal cord and their function/responsability?

A

From the superior to the inferior:

CTLS

  1. Cervical
    - efferent nerves from the cervical section innervate/supply muscles in the neck, shoulders, arms, and hands
    - afferent nerves bring in sensory information from this same region
    - C3 and C5 innervate the diaphragm
    - its sweeling corresponds with the many inputs and outputs of the arms
  2. Thoratic
  • these nerves innervate the middle trunk area, including the heart, lungs and abdominal muscles
  • certain branches off the spinal cord in the thoratic area are responsible for changing various internal organs during flight-or-flight response
  1. Lumbar
  • has pathways that carry motor to the hips, thighs, and knees
  • afferent nerves carry information from the anteiror (front) of the legs to this part of the spinal cord
  • second widest area of the spinal cord
  1. Sacral
    - controls the flexing of the toes
    - nerves that detect sensory information around the genital organs and dorsal (back) aspects of the legs
    - some parasympathetic nerves also supply the colon, bladder and genital organs
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21
Q

What are the similarities between each cross section of the spinal cord

A
  1. Each cross section has a butterfly-shaped section of gray matter, surrounded by white matter
  2. The points of exit and entrance for efferent and afferent nerves

DIFFERENCE: The ratio of white to gray matter

22
Q

The PNS can be divided into 3 main systems. What are they

A

Somatic: Voluntary movements

Autonomic: Involuntary movements and functions. Also includes the sympathetic (fightor flight) and parasympathetic (read and digest)

Enteric: Digestive functions

23
Q

Test yourself on the cranial nerves!

24
Q

What are the 2 types of stroke and what are they?

A

Ischemic and Hemorrhagic

Ischemic: Happens when normal blood flow is disrupted, causing the deathof cells through oxygen deprivation

Hemorrhagic: results from a burst blood vessel, which causes bleeding into the brain, and therefore, increased intracranial pressure.

Also, as blood has dramatically different properties compared to the solution the brain cells like in, the neurosn could trigger a self destruction program

25
Which type of stroke is generally more deadly?
Hemorrhagic
26
What is the purpose of the Blood Brain Barrier (BBB)?
The BBB is a layer of cells that acts as a filter, keeping the harmful substances and pathogens out, while allowing the helpful substances into the brain
27
Where can the BBB be found?
It surrounds the blood vessels in the brain
28
What type of cells is the BBB made of?
It is made up of endothelial cells and a type of glial cell called an astrocyte
29
How many vesicles are there in the brain and what is their purpose
4 They are filled with cerebrospinal fluid (a salty solution), which is what causes the brain to float within the skull (Salt causes a greater buyoncy), which protects thebrain fromfriction against the skull
30
Where is CSF found?
- in the ventricles (providng the brain's ability to float) - within the meninges (providing cushioning)
31
How much CSF is within the body and how much does the body produce each day?
150ml in the body 1/2 a liter produced each day
32
What is hydrocephalus?
A condition in which the patient's amount of CSF is increased, which increases intracranial pressure Adults' skulls are hardened and unmoving, but with children, as their skulls are not fully developed they might have bulging parts of the skull
33
What are the 3 membranes of the meninges?
Dura mater - attached to the inside of the skull with resilient sutures between the membrane and the plates of cranium - tough Arachnoid mater - middle layer - made up of delicate fibres that resemble a spider web - allows CSF to exit the sub-arachnoid space and enter the bloodstrem Pia mater - thin tissue in direct contact with the brain - allows blood vessels to pass through and nourish the brain
34
Neurons are electroactive. What does this mean?
They exhibit eletrical activity and respond to electrical stimuli They are not the only cells in the body that are neuroactive
35
What is neurogenisis?
The process in which new neurons form (other cells regenerate often)
36
What is the purpose of spines on dendrites?
They are like bumps on the dendrites that allow neurons to recieve information from various places at once
37
Where are the largest somata?
In the Bletz cells of the motor cortex
38
What are nerves?
Multiple axons that travel together
39
What is the longest axon/nervein the body?
The sciatic nerve
40
What is the purpose of the axon hillock?
- the axon hillock is responsible for deciding whther or not to pass a sginal onto the next cell - to decide, the killock performs a complex set of arthmetic that weighs all incoming signals
41
What is it called when substances are transported away from the soma? And towards?
Away: Anterograde transport Towards: Retrograde transport
42
What is the active zone and where is it found?
- found in the axon terminal - made up of a variey of proteins that are important for the process of neurotransmitter release
43
What are vesicles?
They are small, spherecial packages of cell membrane that are coated in special proteins Within, there are the neurotransmitters that the neurons use for communication
44
What is the myelin sheath?
- myelin is comprised of tighly-wrapped (sometimes wrapped 250-300 times) layers of cell membrane that surround a short section of the axon - Purposes: - increases the speed by which electrical signals are transmitted - increases thickness of the cell membrane around the axon, which causes signals to be passed down more reliable
45
What is Nodes of Ranvier?
Sections of the axon that are not covered my the myelin sheath
46
What is multiple sclerosis?
- a disease that results from the destruction of myelin in the CNS - this causes signals to not be transmitted properly (body to brain and vice versa) - no known treatment now
47
What are the 3 ways to classify neurons based on their anatomy?
Unipolar cell - a singular extension coming off the soma - humans DO NOT have unipolar cells Bipolar cell - a single axon and dendrite - they are not common, but are found in the eyes Multipolar cell - most common -multpile dendrites and one axon
48
What are the 3 ways to classify neurons based on their function?
Sensory - afferent neurons Motor - efferent neurons Interneuron - a relay between sensory or motor neurons - they play an important part of reflex circuits
49
What are the 5 types of glia and what do they do?
1. Astrocytes - They maintain the BBB 2. Olgliodendrocytes - they add a layer of myelin around the axons of nearby CNS neurons 3. Schwann Cells - they add a layer of myelin around the axons of nearby PNS neurons 4. Microglia - As immune cells, they travel throughout the brain and spinal cord and identify and destroy clumps of proteins, dead/dying cells, or foreign pathogens (microorganism or toxin) that enter the brain 5. Ependymal cells - found along the inner lining of ventricles - they produce CSF
50