Brain and Behaviour Unit 5 Flashcards
two major kinds of cells in the nervous system
Neurons
Glial cells
What are Neurons
Cells specialized to receive, process and transmit information with electrical and chemical signals
Have about 100 billion- each has about a thousand connections to other neurons
Major parts of neuron
Soma (cell body)
Dendrites
Axon
Nerves
Myelin sheath
Axon terminals
Soma (cell body)
Life support centre, provides energy for neurons
Dendrites
Off of the soma (cell body)
gather incoming messages from other neurons, which influences the messages sent by the neurons its attached to
Axon
Off of the soma (cell body)
Each neuron only has one axon , but they branch
Nerves
Bunch of axons bundled together
Myelin sheath
Wraps around neurons and speeds up pace of signals sent by the neurons
Conduction
Electrical signals (action potential)
Resting potential
-70 millivolts
Neuron is in an inactive state
Ions
Molecules with a positive or negative electrical charge
Axon
Negative charge inside, positive charge outside
Due to different concentrations of ions inside and outside the cell
Sodium
Na+
More sodium + outside the cell at resting potential
Sodium potassium pumps
maintain negative charges inside axon - 3+ ions out, 2- ions in
Ion channels
gates in axon membrane, block most ions from entering unless open
Sodium ions channels closed at resting potential (that’s why - inside at resting)
Axon membranes are barriers to some ions (sodium cannot pass through but water and oxygen/co2 can)
How to open ion channels?
Changes in electrical charge- voltage gated Threshold of excitation(blue part): -50 millivolts
Voltage at which sodium ion channels open
Action potential
Neurons fired (electrical signal)
Electrical charge inside axon briefly becomes positive and outside negative
Note contrast with action potential
Increase voltage to +40 millivolts inside axon: (max green part)
All or nothing law
If the neuron fires and a action potential is generated, it always reaches +40 millivolts, so you either get one or you don’t
Either resting -70 or action potential +40
Propagation of action potential
Action potential move down the axon from cell body to the axon terminals (like dominos or wave at a hockey game)
Same thing happens over and over, the action potential follows through the axon
Negative after-potential and refractory period
The positive charge from the action potential is just a brief change, this is a bigger one
negative electrical charge after an action potential is more negative then the resting potential
Sodium ion channels close : this brings the axon back to a negative charge:
Axon repolarizes: potassium ion channels open
Refractory period: action potential cannot be triggered during this phase (further away)- resting potential returns after one millisecond
Synapse (gap/cleft)
Gap between the axon terminal of the presynaptic (sending) neuron and the dendrites of the postsynaptic (receiving neuron)
Synaptic vesicles
Located in the presynaptic neuron
Chemical messengers called neurotransmitters are stored here
Axon terminal
Release neurotransmitters into synapse when action potential reaches the axon terminal
Receptor sites
on post synaptic dendrite
When neurotransmitters bind to these sites, they affect the level of excitation and therefore whether the postsynaptic neuron fires (reach an action potential)
Neurotransmitters
Bind to receptor sites