brain abscess Flashcards
1
Q
considerations of antibiotic treatment
A
physiological properties of BBB and BCSF barrier are distinct. penetration of drugs into CSF and brain tissue differ
2
Q
which antibiotics are used
A
ampicillin, penicillin, cefuroxime, cefotaxime, ceftazidime, metronidazole –> therapeutic concentrations in intracranial pus
3
Q
sinugenic/ odontogenic abscess
A
cefotaxime 2g 6hrly
metronidazole 500mg 8hrly (both IV)
4
Q
otogenic abscess
A
benzyl penicillin 2.4g 6hrly
ceftazidime 2g 8hrly
metronidazole 500mg 8hrly (all IV)