brain abscess Flashcards

1
Q

considerations of antibiotic treatment

A

physiological properties of BBB and BCSF barrier are distinct. penetration of drugs into CSF and brain tissue differ

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2
Q

which antibiotics are used

A

ampicillin, penicillin, cefuroxime, cefotaxime, ceftazidime, metronidazole –> therapeutic concentrations in intracranial pus

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3
Q

sinugenic/ odontogenic abscess

A

cefotaxime 2g 6hrly

metronidazole 500mg 8hrly (both IV)

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4
Q

otogenic abscess

A

benzyl penicillin 2.4g 6hrly
ceftazidime 2g 8hrly
metronidazole 500mg 8hrly (all IV)

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