Box 14.1 Drugs that Interact with Monoamine Oxidase Inhibitors

Question 1

Which drug interacts with Monoamine Oxidase Inhibitors (1)

Answer 1

Over the counter medication cold, allergies, congestion

Any product containing epinedrine, phenylephrine hydrochloride, or phenylpropanolamine

Question 2

Which drug interacts with Monoamine Oxidase Inhibitors
(2)

Answer 2

Trycyclic Antidepressants
- impiramine
- amitriptylene

Question 3

Which drug interacts with Monoamine Oxidase Inhibitors
(3)

Answer 3

Narcotocs

Question 4

Which drug interacts with Monoamine Oxidase Inhibitors
(4)

Answer 4

Antihypertensives
- methylopa
- guanethidine
- reserpine

Question 5

Which drug interacts with Monoamine Oxidase Inhibitors
(5)

Answer 5

Amine precursors
- levodopa
- L-tryptophan

Question 6

Which drug interacts with Monoamine Oxidase Inhibitors
(6)

Answer 6

Sedatives
Alcohol
Barbiturates
Benzodiazepines

Question 7

Which drug interacts with Monoamine Oxidase Inhibitors
(7)

Answer 7

General Anesthetics

Question 8

Which drug interacts with Monoamine Oxidase Inhibitors
(8)

Answer 8

Stimulants
- amphetamines
- cocaine

Question 9

(Box 14.6)
What is a toxic reaction / effect(s) of Monoamine Oxidase Inhibitors?

Answer 9

-Hypersensitive crisis

-Severe Headaches

-Tachycardia (fast heart rate)

-Palpitations (sensation that the
heart is racing, pounding, fluttering, or skipping a beat)

-Hypertension

• Nausea/ Vomitting

Question 10

(Box 14.6)
What do do at a toxic reaction / effect(s) of Monoamine Oxidase Inhibitors?

Answer 10

Pt should go to the local emergency department immediately
BP should be checked
meds to lower bp should be given; 5mg IV phentolamine or sublingual nifedipine to promote vasodilation.

Pt’ may be prescribed a 10 mg nifeddipine capsule to carry in case of an emergency

Question 11

(Box 14.6)
Family teaching about Monoamine Oxidase Inhibitors

Answer 11

• Avoid aged, cured, ripened, ODC (unless prescribed) with HCP

Give PT wallet card describing MAOI’s regiment

Instruct pt to avoid asain restaurant’s (sherry, brewer’s yeast)

• tell pt to go to emergency dep. immediately if severe headaches arises
  BP should be monitored during 1st 6 weeks of treatment hyper and hypo bp
• After MAOI’s are stopped, instruct pt that dietary and drug restrictions should be maintained for 14 day’s