BotMed Flashcards
Achillea Millefolium
“Yarrow”
Constituents: thujone, sesquiterpene lactones, bioflavanoids, bitters, alkaloids, tannins, coumarins
Actions: Hemostatic, bitter, anti-inflammatory, diaphoretic
Indications:
Topical: wounds, skin ulcers
Internal: passive hemorrhage, meno/metrorrhagia, hematuria, hemorrhoids, poor digestions
CI: GERD, active peptic ulcer, gastritis, biliary obstruction, acute cholelithiasis, diarrhea, ASTERACEA ALLERGY
Large doses CI in Pgx
AdvFx: emenagogue, abortifacient, convulsions (from thujone)
Interactions: Antagonistic effects with PPIs, may decrease absorption of meds dt increased gut motility
Constituents: thujone, sesquiterpene lactones, bioflavanoids, bitters, alkaloids, tannins, coumarins
Actions: Hemostatic, bitter, anti-inflammatory, diaphoretic
Indications:
Topical: wounds, skin ulcers
Internal: passive hemorrhage, meno/metrorrhagia, hematuria, hemorrhoids, poor digestions
CI: GERD, active peptic ulcer, gastritis, biliary obstruction, acute cholelithiasis, diarrhea, ASTERACEA ALLERGY
Large doses CI in Pgx
AdvFx: emenagogue, abortifacient, convulsions (from thujone)
Interactions: Antagonistic effects with PPIs, may decrease absorption of meds dt increased gut motility
Achillea Millefolium (Yarrow)
Aconitum Napellus
“Monkshood”
Constituents (root and leaf): Tropane alkaloids
Actions: andoyne, anti-pyretic, sensory and motor depressant, sedative
Indications: neuralgias, pain
CI: Pregnancy, Lactation, high or sustained doses
AdvFX: narrow therapeutic window, lethal (this is a LOW DOSE herb). OD Sxs (Parasympatholytic): numb mouth, throat, hands, dizziness, restless, loss of speech, HA, pinpoint pupils, arrhythmias, chest pains, VFIB, sweat, hypothermia, anxiety, diarrhea, convulsions, death from cardiac/pulm paralysis
Interactions: none known
“Monkshood”
Constituents (root and leaf): Tropane alkaloids
Actions: andoyne, anti-pyretic, sensory and motor depressant, sedative
Indications: neuralgias, pain
CI: Pregnancy, Lactation, high or sustained doses
AdvFX: narrow therapeutic window, lethal (this is a LOW DOSE herb). OD Sxs (Parasympatholytic): numb mouth, throat, hands, dizziness, restless, loss of speech, HA, pinpoint pupils, arrhythmias, chest pains, VFIB, sweat, hypothermia, anxiety, diarrhea, convulsions, death from cardiac/pulm paralysis
Interactions: none known
Aconitum Napellus
Actea (Cimicifuga) Racemosa
“Black Cohosh”
Constituents: Triterpene glycosides, aromatic acids, fatty acids, starch, volatile oils
Actions: Uterine tonic, pituitary/estrogen mimetic, parturifacient, anti-rheumatic, spasmolytic, antitussive, nervine
Indications: dysmenorrhea, PMS, menopause, early labor, rheumatism, myalgia, OA, RA, whooping cough, tinnitus
CI: First trimester of pregnancy, lactation, estrogen dependent tumors
AdvFX: Nausea
OD Sxs: sedative, bradycardia, hypotension, blurred vision, N/V, HA
Interactions: HRT therapy leading to estrogen excess (but does not affect uterus), reduces hot flashes from tamoxifen.
Constituents: Triterpene glycosides, aromatic acids, fatty acids, starch, volatile oils
Actions: Uterine tonic, pituitary/estrogen mimetic, parturifacient, anti-rheumatic, spasmolytic, antitussive, nervine
Indications: dysmenorrhea, PMS, menopause, early labor, rheumatism, myalgia, OA, RA, whooping cough, tinnitus
CI: First trimester of pregnancy, lactation, estrogen dependent tumors
AdvFX: Nausea
OD Sxs: sedative, bradycardia, hypotension, blurred vision, N/V, HA
Interactions: HRT therapy leading to estrogen excess (but does not affect uterus), reduces hot flashes from tamoxifen.
Actea (Cimicifuga) Racemosa (Black Cohosh)
Aesculus Hippocastanum
“Horse Chestnut”
Constituents: glycoside lactones, saponins
Actions: astringent, vasoconstrictive, veno-tonic, anti-inflammatory, mild expectorant
Indications: bruises, hemorrhoids, pruritis ani, varicose veins, venous insufficiency, DVT, thrombophlebitis, edema, hemorrhoids, chronic prostitis
CI: high doses
AdvFX: nausea. unprocessed fruit is highly toxic, IM injection may cause hepatitis or renal failure.
Interactions: N/A
Allium Sepa/ Allium Sativum
“Onion”/ “Garlic”
Constituents: disulfides, phenolic acids, flavanoids, sterols, saponins, pectin, oils
Actions: Anti-atherosclerotic, hypolipidemic, hypoglycemic, antiplatelet, immune modulator, antimicrobial, carminitive, anti-helminthic (garlic)
Indications: dermatophytosis, onychomycosis, warts, vaginitis, otitis media, athersclerosis, hypercoagulation, dyslipidemia, intermittent claudication, HTN, DM, insufficient lactation, candidiasis, gastroenteritis, h.pylori, UTIs, internal parasites (garlic)
CI: bleeding d/o, anticoag therapy, thyroid disease (inhibits iodine uptake!)
AdvFX: increased bleeding time, may worsen colicky infants through breast milk
Interactions: potentiates warfarin and other anticoagulants, insulin, hypoglycemic drugs
Aloe Vera (Gel)
Constituents: polysaccharides
Actions: inflammation/immune moderator, vulnerary, demulcent
Indications: burns, wounds, frost bite, ulcerations, stretch marks, warts, varicose, veins, gastritis, IBD, peptic ulcer, interstitial/infectious cystitis
CI: 3rd degree burns, deep or infected wounds, wounds healing by secondary intention
AdvFX: very safe herd, may cause diarrhea or abd cramping
Interactions: hypoglycemia effects with glyburide
may reduce absorption of drugs dt polysaccharide action
Aloe Vera (Latex)
Constituents: anthraquinone glycosides
Actions: cathartic
Indications: atonic constipation
CI: use over 10 days, bulimia, obstruction, spastic constipation, acute GI inflammation, unknown abdominal pain, under 12yo, pregnancy, lactation
AdvFX: acute GI cramping, colic, harmless red urine/feces, pseudomelanosis coli, diarrhea
Interactions: Avoid hypokalemic drugs (Diuretics, furosemide, HCTZ, corticosteroids, cardiac glycosides (digoxin, digitalis, leonorus), anti-arrythmics (atenolol, propranolol, amiodarone), pseudoephedrine, GLYCYRRHIZA
may reduce drug absorption dt increased TT
Althea Officinalis
"Marshmallow" Constituents: Mucilage, polysaccharides Actions: demulcent, vulnerary Indications: (root): gastritis, PUD, IBS, colitis (leaves): Pharyngitis, laryngitis, bronchitis, dry cough, asthma, interstitial cystitis, lower UTI
CI: wet cough
AdvFX: N/A
Interactions: may reduce drug abs dt polysaccharides
Angelica Sinensis
“Dong quai”
Constituents: coumarins, polysaccharides, ferulic acid
Actions: uterine tonic, liver tonic, spasmolytic, anti-inflammatory, analgesic, sedative
Indications: amenorrhea, dysmenorrhea, endometritis, estrogen imbalance, menopause, PMS
Hepatitis, cirrhosis, poor digestion, migraine, HA, arthritis
CI: menorrhagia, bleeding diathesis
AdvFX: slight anti-platelet activity, otherwise safe
Interactions: potentiates anticoagulants (warfarin)
Arctium Lappa
“Burdock”
Constituents: lignins, sesquiterpene lactones, tannins, mucilage, pectin
Actions: alterative, bitter, hepatoprotective, diuretic, diaphoretic, anti-pyretic, phytoestrogen, anti-rheumatic, antimicrobial, hypoglycemic, demulcent
Indications:
(root) : psoriasis, eczema, rheumatism, OA, RA, poor digestions (hypochlorhydria, dyspepsia, biliary insufficiency, dyskinesia, anorexia, atonic constipation, gas, hepatitis
(leaves) : mastitis, OA, RA, sprains
CI: GERD, active PUD, gastritis, biliary obstruction, acute cholelithiasis, diarrhea
PREGNANCY (at high doses)
AdvFX: nausea
Interactions: antagonistic effect with PPIs, may require insuin adjustment, decreased drug abs dt increased gut motility
Arctostaphylos uva-ursi
“bearberry”
Constituents: glycosides, flavonoids, tannins
Actions: urinary antiseptic and sedative
Indications: Alkali UTIs, chronic bladder irritation with pain, tenesmus, blood mucus
CI: pregnancy, use beyond 10 days
AdvFX: Nausea, chronic use may be carcinogenis
OD Sxs: tinnitus, vomiting, delirium, convulsions, collapse, death
Interactions: Vitamin C, cranberry acidify urine
Arnica Montana
Constituents: sesquiterpene lactones, flavonoids, polysaccharides
Actions: topical vulnerary, anti-inflammatory, immune stimulant
Indictions: bruises, phlebitis, rheumatism, strains/sprains, myalgia, small wounds, skin ulcers
CI: use over large areas of broken skin, ASTERACEA allergy, internal use
AdvFX: gastroenteritis, HA, nervous disturbance, altered HR, HTN, muscle weakness, dyspnea, drowsiness, cardiovasc collapse, convulsions, coma, death
Interactions: N/A
Artemisia Absinthum
“Wormwood”
Constituents: sesquiterpene lactones (thujone), lignans, flavanoids
Actions: bitter, vermifuge, febrifuge, nervine, carminitive, antimicrobial, antiseptic, antidepressant, emmenagogue
Indications: poor digestion (hypochlorhydria, dyspepsia), biliary insufficiency, biliary dyskinesia, anorexia, intestinal roundworms, pinworms, depression, colds, influenza
CI: Large doses, pregnancy, lactation
GERD, active PUD, gastritis, obstruction, cholelithiasis, ASTERACEA allergy
AdvFX: intoxication, vomiting, Gi upset, HA, dizziness, impotence, convulsions
Interactions: PPIs, dec drug absoprtion dt increased motility
Artemisia Annua
“sweet annie”
Constituents: sesquiterpene lactones, volatile oils
Actions: antiparasitic, antimicrobial, antineoplastic, bitter
Indications: MALARIA, parasitic infx, cancer
CI: pregnancy, lactation, ASTERACEA allergy
AdvFX: nausea, whole herb is safe but sesquiterpene lactones may be neurotoxic
Interactions: combine with IRON for optimum efficiency
Artemisia Vulgaris
“Mugwort”
Constituents: sesquiterpene lactones, volatile oil, falvanoids, coumarins
Actions: bitter, nervine, emmenagogue, carminative
Indications: poor digestion, depression, amenorrhea
CI: GERD, active, PUD, obstruction (GI and biliary), Pregnancy, Lactation, ASTERACEA allergy, diarrhea
AdvFX: (from thujone) emmenagogue, abortifacient, convulsions
Interactions: PPIs, potentiates hypoglycemics, dec drug abs dt increased motility
Ascelpias Tuberosa
“pleurisy root”
Constituents: Glucosides, tannins, resins
Actions: diaphoretic, expectorant, anti-tussive, antispasmodic
Indications: infection, respiratory tract congestion (bronchitis, pleurisy, pertussis, pneumonia, cough, cold, flu)
CI: Pregnancy, large doses for several days
AdvFX: N/V, GI upset, diarrhea, anorexia
Interactions: cardiac glycosides (digoxin, leonorus convallaria, digitalis)
Aspidosperma Quebracho
Constituents: alkaloids, tannins
Actions: stimulating expectorant, anti-tussive, antimicrobial
Indications: Dyspnea, asthma, emphysema, TB, hemoptysis, wet cough, bronchitis, pneumonia, periodic fevers
CI: dry cough, pregnancy, lactation, infants, long-term use
AdvFX: N/V
Interactions: N/A
Astragalus Membranaceus
Constituents: triterpenoid saponins, glycosides, polysaccharides, flavonoids
Actions: adaptogen, immune modulator, antibacterial, antiviral, hepatoprotective, cardioprotective, hypoglycemic
Indications: depressed immune system, infection (viral myocardiopathy), pharyngitis, tonsilitis, cancer, male infertility
CI: may exacerbate AD and acute infections
AdvFX: May increase fibrin formation
Interactions: potentiates acyclovir, IF 1, IF2. may antagonize corticosteroids.
reduced drug absorption dt polysaccharides
Atropa Belladonna
Constituents: atropine, tropane alkaloids
Actions: spasmolytic, vasoconstrictor, bronchodilator, analgesic, ANTI-MUSCARINIC (sympathetic/ anti-cholinergic)
Indications: smooth muscle spasm, spastic constipation, asthma, Parkinsonism, tremors
Pain from SM contractions- PMS, dysmenorrhea, GERD, peptic ulcer, gastritis, hyperchlorhydria
CI: Long term use, High doses, BPH, urinary retention, prostate cancer, tachycardia, arrhythmia, closed-angle glaucoma, acute pulmonary edema, GI stenosis, megacolon, pregnancy, lactation, children
AdvFX: hyperthermia, flushed face, dry membranes, mydriasis, blurred vision, giddiness, loquacity, delirium, tachycardia, hyperventilation, sleepiness, hallucinations, dysphagia, convulsion, coma, death
“Hot as a hare, red as a beet, dry as a bone, blind as a bat, mad as a hatter”
Interactions: potentiates anticholinergics (atropine, burproprion, dextromethorphan, dicyclomine, diphenhydramine, tolterodine tricyclic antidepressants, amantadine…
Avena Sativa
“oat”
Constituents: starch, polysaccharides, fiber, indole alkaloids
Actions: anxiolytic, nervine, hypolipidemic, nutritive
Indications: eczema, inflamed skin, seborrhea, fatigue, anxiety, general debility, hyperlipidemia, cardiac rheumatism, nicotine/opiate withdrawl.
CI: none
AdvFX: none
Interactions: none
Bacopa Monierri
“Brami”
Constituents: triterpenoid saponins
Actions: analgesic, anti-helminthis, antifungal, antioxidant
Indications: cognition, anxiety, epilepsy, poor memory
CI: none
AdvFX: palpitations, nausea, dry mouth, thirst, fatigue
Interactions: may induce CYP450 (increase thyroid hormon and potentiate levothyroxine)
may potentiate Ca-channel blockers (amlodipine) and sedatives, antihistamines, barbiturates, benzodiazepines, opiates, trazadone, zolpidem
Baptisia Tinctoria
“wild indigo”
Constituents: alkaloids, isoflavones, flavanoids, coumarins, polysaccharides
Actions: immune stimulant, anti-microbial, anti-catarrhal, alterative
Indications: URI with catarrh, pharyngitis, tonsilitis, mastitis, delirium with fever, chronic fatigue
CI: long term use, high dose, pregnancy, lactation
AdvFX: anorexia, N/V, hypersalivation, tachypnea, tachycardia, respiratory paralysis
Interactions: none
Berberis (Mahonia) Aquifolium
“Oregon Grape”
Constituents: isoquinolone alkaloids
Actions: bitter, alterative, hepatoprotective, cholagogue
Indications: poor digestion, dyskinesia, anorexia, atopic constipation, gas
Chronic skin disease, acne, candida, mastitis, gastroenteritis, hepatitis, lower UTI, vaginitis, cancer
CI: GERD, active PUD, obstruction, acute cholelithiasis, diarrhea, late pregnancy
AdvFX: N/V, mucus membrane irritation, hypotension, heart failure, convulsions, parethesias
Interactions: PPIs, increased gut motility, may cause vaginal dysbiosis
Berberis Vulgaris
“Barberry”
Constituents: isoquinolone alkaloids, chelidonic acid, tannins
Actions: bitter, antimicrobial, cholagogue, choleretic, antiparasitic
Indications: poor digestion, gastritis, Hpylori, gastroenteritis, chronic hepatitis, liver disease, gallstones, malaria, splenomegaly
CI: GERD, active PUD, obstruction, hyperbilirubinemia, kidney disease, acute hepatitis, cirrhosis, liver cancer, pregnancy, lactation
AdvFX: N/V, mucus membranes irritation, hypotension, heart failure, convulsions, paresthesias
Interactions: PPIs, potentiates barbiturates (phenobarbital), dec drug abs dt increased gut motility.
Boswelia Serrata
“Frankincense”
Constituents: resins, volatile oils
Actions: anti-inflammatory, analgesic, antiseptic, astringent
Indications: asthma, chrons, UC, OA, RA, chronic prostatitis, inflammation
CI: none
AdvFX: GI upset, pain
Interations: enhances NSAIDs (aspirin, ibuprofen, naproxen, celecoxib)
Bryonia Alba
Constituents: cucurbitacins, fatty acids, volatile oils, tannins
Actions: anodyne, sedative, anti-rheumatic, antiviral, cathartic
Indications: pain, pain from ovarian cysts, infection, rheumatism, PUD, asthma, bronchitis, pleurisy
CI: pregnancy, lactation, not for internal use
AdvFX: abd pain, N/V, diarrhea, hypothermia, bronchial irritation, mydriasis, HA, delirium, dizziness, cold sweat, jaundice, kidney irritation, weak pulse, tachycardia, paralysis, collapse
Interactions: none
Calendula Officinalis
“Marigold”
Constituents: flavonoids, triterpenoids, carotenoids, resin, polysaccharides, tannins
Actions: demulcent, anti-inflammatory, vulnerary, anti-pruritic, antiseptic
Indications: dermatitis, wounds, skin ulcers, chronic prostitis, periodontal disease, gingivitis, conjunctivitis
PUD, indigestion, hepatic congestion.
CI: topically on deep wounds, ASTERACEA FAMILY
AdvFX: none
Interactions: none
Camella sinensis
“Tea”
Constituents: polyphenols, caffeine, L-theonine
Actions: anti-tumor, antimicrobial, stimulant, diuretic, anti-inflammatory, antioxidant
Indications: asthma, cancer prevention, infection, cavity prevention, weight loss, memory enhancement, stimulant
CI: children, beriberi
(CVD, Kidney dz, duodenal ulcer, psychological do, pregnancy- theoretically)
AdvFX: insomnia, agitation, tremors, potentially hepatotoixic
Interactions: Reduces Iron absorption
potentiates: acetaminophen, clopidogrel, doxorubicin, warfarin, CNS stimulants (caffeine, MDMA, dextromethorphan, pseudoephedrine),
Antagonizes sedatives: bendryl, barbiturates, benzos, opiates, trazadone, zolpidem
caffeine effects
Cannabis sativa
“Marijuana”
Constituents: cannabinoids (THC, CBD), flavonoids
Actions: analgesic, sedative, anti-emetic, antiinflammatory, hypotensive, psychoactive
Indications: cancer (cachexia, pain), glaucoma, MS, cerebral palsy, HTN, pain, anxiety, depression, insomnia, neuropathy, N/V, AIDS, asthma
CI: Pregnancy, Lactation, schizophrenia, prolonged inhalation, use of heavy equipment
AdvFX: dry mouth, impaired short-term memory, paranoia, anxiety, panic attacks
(long term): decreased LH, FSH, genital dysfxn, infertility, impaired judgement, impaired REM sleep, arrested for illegal use
Interactions: potentiates opiates (codeine, hydrocodone, morphine, oxycodone, methadone), barbiturates (phenobarbital)
Capsella bursa-pastoris
“Shephards purse”
Constituents: volatile oils, bioflavanoids
Actions: diuretic, astringent, styptic
Indications: mild menorrhagia, metrorrhagia, mild post-partum hemorrhage, hemorrhoids
CI: major bleeding, pregnancy
AdvFX: none
Interactions: may potentiate anticoagulants (warfarin)
Capsicum Frutescens
“Cayenne”
Constituents: phenolic acids, carotenoids, saponins
Actions: anodyne, anti-neuralgic, anti-pruritic (depletes substance P), counter-irritant, anti-inflammatory.
digestive stimulant, carminitive, hypolipidemic, anticatarrhal, antiplatelet, circulatory stimulant
Indications: diabetic neuropathy, pruritis, psoriasis, OA, RA, migraines
hypochlorhydria, Hpylori, maldigestion, dyspepsia, biliary insufficiency, atonic constipation, athersclerosis, stimulant, capillary atony, hypercoagulation
CI: contact with eyes, GERD, active PUD, obstruction, pregnancy, bleeding do
AdvFX: N/V, diarrhea, abdominal pain
Interactions: anticoagulants (warfarin), inhibits CYP450, may aggravate cough from ACE-inhibitors
Cassia Spp.
Senna Alexandrina
Constituents: anthraquinone glycosides, mucilage, flavonoids
Actions: cathartic, stimulant
Indications: ATONIC CONSTIPATION
CI: use beyond 10 days, bulimia, obstruction, spastic constipation, acute GI inflammation, unknown abdominal pain, under 12yo, pregnancy, SAFE DURING LACTATION
AdvFX: GI cramps, colic, harmless red urine/feces, p.coli, diarrhea, miscarraige
Interactions: Avoid with hypokalemic drugs (diuretics, corticosteroids, cardiac glycosides, anti-arrythmics, pseudoephedrine, Glycyrrhiza)
Caulophyllum thalictroides
“Blue cohosh”
Constituents: quinolizidine alkaloids, steroidal saponins
Actions: Uterine tonic, parturifacient, emmenagogue, anti-inflammatory, anti-rheumatic, diuretic, diaphoretic
Indications: amenorrhea, menorrhagia, dysmenorrhea, cyclic mastalgia, female infertility, uterine prolapse, facilitate labor, rheumatism, OA, RA
CI: early pregnancy
AdvFX: dermatitis, GI irritation, nausea, HA, HTN, pharyngitis, thirst, mydriasis, weakness, incoordination, CV collapse, convulsions, 2 cases of fetal harm
Interactions: may interfere with nitroglycerin dt vasoconstriction
Ceanothus Americanus
“Jersey tea”
Constituents: tannins, alkaloids
Actions: hepatoprotective, splenoprotective, lymphatics, alterative, astringent, anti-spasmodic, hypotensive, expectorant, hemostatic
Indications: fatty liver, hepatitis, splenomegaly, lymphadenopathy, bronchitis, asthma, cough, dysentery, GI bleeding, malaria, thalassemia, SCanemia, TB, non-hodgkins lymphoma, chronic EBV, skin conditions
CI: none
AdvFX: may increase clotting
Interactions: may antagonize warfarin
Centella asiatica
“Gotu Kola”
Constituents: triterpenoid sapnonins
Actions: nervine, anti-pyretic, vulnerary, venotonic, keratolytic, antimycobacterial, nootropic
Indications: insomnia, dementia, poor memory, mycobacterial infx, sore throat, tonsillitis, cystitis, hepatitis, measles, wounds (scars, keloids, ulcers), leprosy, eczema, syphillis, varicose veins, chronic venous insufficiency
CI: none
AdvFX: HA, dizziness, HTN, hematochezia, pruritis, photosensitivity, contact derm.
Interactions: none
Chamaelirium Luteum
“False unicorn”
Constituents: steroidal saponins
Actions: uterine tonic, ovarian tonic, emmengogue, diuretic
Indications: amenorrhea, dysmenorrhea, endometriosis, leucorrhea, estrogen imbalance, menopause, female infertility, uterine infections, ovarian cysts, leiomyomas, PMS, threatened miscarraige, premature labor, dyspepsia
CI: early pregnancy, GI irritation
AdvFX: N/V, slight antiplatelet activity
Interactions: may potentiate warfarin
Chelidonium Majus
“Greater Celandine”
Constituents: isoquinolone alkaloids, flavonoids, phenolic acids
Actions: alterative, choleretic, cholagogue, bitter, diuretic, anti-inflammatory, antitussive, antimicrobial, antiviral (HPV).
Indications: topical warts, eczema, corns, malignant tumors, biliary insufficiency, gall stone prevention, whooping cough, asthma
CI: biliary obstruction, hepatic failure, acute diarrhea, cholelithiasis, hepatitis, cholecystitis, unconjugated hyperbilirubinemia, pregnancy, lactation, children.
AdvFX: N/V, burning in mouth, abd pain, diarrhea, topical dermatitis, stupor, coma
Interactions: none
Chionanthus virginicus
“Fringe Tree”
Constituents: lignan glycosides, saponins
Actions: cholagogue, alterative, bitter, diuretic, mild laxative, anti-emetic, antipyretic
Indications: wounds, inflammation, liver and GB dysfxn, jaundice, hepatomegaly, biliary insufficiency, gall stones, chronic skin conditions, constipation, dyspepsia, typhoid fever, malaria
CI: biliary obstruction, hepatic failure, acute diarrhea, acute cholelithiasis, hepatitis, cholecystitis, unconjugated hyperbilirubinemia
AdvFX: none
Interactions: none
Cineraria (Centaurium) Maritima
“Dusty Miller”
Constituents: unsaturrated pyrrolizidine alkaloids, sesquiterpine lactones
Actions: Anti-cataract
Indications: topical application to cataracts
CI: Internal use, over broken skin, pregnancy, lactation, ASTERACEA allergy
AdvFX: nausea, hepato veo-occlusive disease, hepatic failure
Interactions: synergistic with hepatotoxic drugs
Cinnamomum Zeylanicum
“Cinnamon”
Constituents: monoterpenoids, tannins, essential oils, lignans
Actions: astringent, carminative, antibacterial (Hpylori), antimicrobial, vasodilator, diaphoretic, antispasmodic
Indications:
(topical): fungal infx, along spine for cough, relaxation
(internal): hemorrhage, menorrhagia, metrorrhagia, hemoptysis, diarrhea, hypochlorhydria, dyspepsia, Hpylori ulcer, maldigestion, biliary insufficiency, dyskinesia, anorexia, atonic constipation, gas
CI: GERD, gastritis, obstruction, high doses of EO in pregnancy
AdvFX: OD of essential oil: N/V, Convulsions, pulmonary edema, liver damage, kidney damage,
Interactions: EO may deplete glutathione in liver with long-term use, tannins may reduce drug absorption
Coleus Forskohlii
Constituents: Diterpene glycosides
Actions: activates adenylate cyclase, positive inotropic, VASODILATOR, hypotensive, bronchodilator, anti-inflammatory, anti-depressant, hypoglycemic, antihistamine, anti-platelet
Indications: Asthma, DILATED CARDIOMYOPATHY, HTN, allergies, glaucoma, hypothyroidism, obesity
CI: active PUD, pregnancy, lactation, children
AdvFX: Gi stimulation, nausea
Interactions: may potentiate cardiac glycosides, anticoagulants, insulin and hypoglycemic drugs, antihistamines
May inrease risk of bleeding from NSAIDs, antagonizes PPIs
Commiphora Mukul
“guggul”
Constituents: sesquiterpenoids, EO
Actions: hypolipidemic, anti-inflammatory
Indications: hyperlipidemia, elevated LDL, inflammation, OA, nodulocystic acne
CI: IBD, pregnancy, lactation, coagulation do
AdvFX: GI symptoms, HA
Interactions: may induce CYP450, may decrease bioavailability of propranolol and diltiazem
Commiphora Myrrha (MolMol)
“Myrrh”
Constituents: resins, gums, EO
Actions: antimicrobial, antioxidant, antiinflammatory, expectorant, antitussive
Indications: excess mucus, leucorrhea, infectious vaginitis, gastroenteritis, dyspepsia, infection, aphthous stomatitis
CI: high doses in pregnancy
AdvFX: nausea
Interactions: may potentiate insulin and hypoglycemic drugs
Convallaria Majalis
“Lily of the valley”
Constituents: cardioactive glycosides, flavonoids
Actions: positive inotropic, negative chronotropic, diuretic, vasoconstrictor
Indications: CHF, atrial arrythmias, hypotension
CI: hypokalemia, hypmagnesemia, hypocalcemia, hypercalcemia, ventricular arrythmias, kidney failure, severe carditis, pregnancy, lactation
AdvFX: Gi symptoms, yellow/green halo around objects, bradycardia, gynecomastia,
Interactions: avoid with hypokalemic drugs (diuretics, corticosteroids, cardiac glycosides, anti-arrythmics, pseudoephedrine, glycyrrhiza
Calcium promotes arrhhtymia, potentiates beta-blockers
Cordyceps Sinensis
“Caterpillar fungus”
Constituents: polysaccharides, unsaturated fatty acids, amino acids
Actions: bronchodilator, antibiotic, anti-cancer
Indications: acute infection, anemia, protects bone marrow, fatigue, asthma, impotence, chronic cough, debility
CI: none
AdvFX: constipation, abd distention, irregular menses, amenorrhea
Interactions: potentiates epinephrine
Corydalis Spp.
Constituents: isoquinoline alkaloids, alkaloids, carboxylic acids
Actions: strong analgesic, hypnotic, sedative, anti-inflammatory, antibacterial, antiarrythmic
Indications: pain management, dysmenorrhea, protects against NSAID ulcers, H.pylori, angina, arrythmias, parasties, gastritis
CI: pregnancy, lactation
AdvFX: decreased menstrual flow, HA, fatigue
Interactions: may have similar action to Ca-channel blockers (amlodipine)
Cratageus Oxycantha (Laevigata)
“Hawthorn”
Constituents: proanthocyanidines (tannins), flavonoids
Actions: anti-atherosclerotic, antioxidant, hypotensive, cariotonic, positive inotropic, negative chronotropic, anti-inflammatory
Indications: CHF, angina, arrhythmias, cardiac weakness, capillary fragility, mild HTN
CI: none
AdvFX: nausea
Interactions: may cause HTN with beta-blockers, tannins may reduce other drug absorptions
Curcuma longa
“Turmeric”
Constituents: curcuminoids, EO
Actions: hepatoprotective, cholagogoue, antioxidant, antiinflammatory, antineoplastic, antibacterial, antiplatelet
Indications: gallstone prevention, jaundice, hepatitis, IBS, cancer, OA, RA, inflammation, asthma, skin do, protection from NSAID ulcers, stroke and MI prevention
CI: biliary obstruction, acute cholelithiasis, hyperchlorhyria, pregnancy
AdvFX: none
Interactions: may potentiate warfarin
Cynara Scolymus
“globe artichoke”
Constituents: flavonoids, phytosterols, sesquiterpene lactones, inulin
Actions: bitter, hypolipidemic
Indications: dyslipidemia, poor digestion
CI: GERD, active PUD, gastritis, biliary obstruction, ASTERACEA allergy
AdvFX: none
Interactions: PPIs, decreased drug abs
Datura stramonium
“Jimson weed”
Constituents: tropane alkaloids
Actions: spasmolytic (anti-muscarinic), secretolytic, analgesic
Indications: acute asthma, smooth muscle spasm, whooping cough, pertussis, epilepsy, delirium
CI: BPH, urinary retention, tachycardia, arrhythmia, closed-angle glaucoma, acute pulmonary edema, GI stenosis, megacolon, pregnancy, lactation, children
AdvFX: hyperthermia, flushed face, dry membranes, mydriasis, blurred vision, giddines, loquacity, delirium, tachycardia, hyperventilation, sleepiness, hallucinations, dysphagia, convulsions, coma
“hot as hare, red as beet, dry as a bone, mad as a hatter, blind as a bad”
Interactions: potentiates anticholinergics (atropine, buproprion, dextromethorphan, dicyclomine, benadryl, tolterodine, TCAs, amantidine)
Digitalis Purpurea
“Foxglove”
Constituents: cardioactive glycosides
Actions: cardiac stimulant, postivie inotropic, negative chronotropic, diuretic, vaso-constrictor
Indications: CHF, atrial arrhythmias
CI: partial heart block, severe carditis, angine, arrythmias, bradycardia, gynecomastia, cardiac hypertrophy, aortic stenosis, kidney failure, hypokalemia, hypomagnesemia, hypocalcemia, hypercalcemia, pregnancy, lactation
AdvFX: Gi symptoms, yellow/green halo around objects, bradycardia, gynecomastia
Interactions: avoid hypokalmeic drugs (see “lily of the valley’/convallaria)
Dioscorea villosa
“wild yam”
Constituents: steroidal saponins, phytosterols, alkaloids, tannins
Actions: spasmolytic, anti-rheumatic, antiinflammatory, diuretic, diaphoretic, hepatic, cholagogue
Indications: dysmenorrhea, endometriosis, PMS, threatened miscarraige, premature labor, smooth muscle spasm, intestinal colic, mylagia, neuralgia, OA, RA, acute rheumatism
CI: biliary obstruction, cholecystitis, biliary cancer, pancreatic cancer, heatitis, cirrhosis, high doses during pregnancy
AdvFX: N/V diarrhea
Interactions: none
Echinacea spp.
Constituents: alkylamides, caffeic acid derivatives, polysaccharides, volatile oils
Actions: immune stimulant, anti-inflammatory, antimicrobial, vulnerary, alterative, antioxidant, topical anodyne
Indications: influenza, URI, pharyngitis, tonsilitits, staph skin infections, vaginitis, mastitis, wounds, skin ulcer, acne, chronic skin disease, cancer, HIV, mycobacterial infx.
CI: ASTERACEA allergy, TB, MS, AIDS, HIV, auto-immune disease, long-term use
AdvFX: none
Interactions: may antagonize immune-suppressive therapy (corticosteroids, adalimumab, cyclosporine)
Eleutherococcus senticosus
“siberian ginseng”
Constituents: phenylpropanoid, triterpenoid saponins, glycosides, polysaccharides, coumarins
Actions: adaptogen, immune modulator, adrenal support
Indications: pharyngitis, tonsilitis, infections, cancer, chronic inflammation, fatigue, hypoadrenocorticism, angina, insomnia
CI: long term use, acute infections, HTN (above 180/90)
AdvFX: insomnia, mild anxiety, irritability
Interactions: may antagonize immune-suppressive therapy
Ephedra sinica
“Ma Huang”
Constituents: alkaloids (ephedrine), phytosterols
Actions: adrenergic agonist, bronchodilator, anti-tussive, anti-allergic, decongestant, anti-secretory, vasoconstrictor, HTNive, diaphoretic, diuretic
Indications: bronchitis, asthma, COPD, sinusitis, allergic rhinitis, enuresis, urinary incontinence, weight loss*
CI: HTN, hyperthyroidism, DM, BPH, glaucoma, CAD, anorexia, pregnancy, lactation, long term use
AdvFX: mild agitation, increased alertness, MI, cerebral vasculitis, stroke
Sympathomimetic OD Sxs: N/V, vertigo, diaphoresis, termor, HA, nervousness, agitation, insomnia, urinary retention, tachycardia, palpitations, dizziness, weakness, seizure
Interactions: potentiates sympathomimetics (albuterol, epinephrine, phenylephrine, pseudoephedrine), caffeine, dextromethorphn, methylphenidate, MAOIs
Antagonizes alpha/beta blockers: atenolol, carvedilol, propranolol, TCAs, increased clearance of dexamethasone
Equisetum Arvense
“Horsetail”
Constituents: saponins, flavonoids, silica, mucilage
Actions: alterative, aquaretic, astringent
Indications: acne, chronic skin dz, lower UTI, urolithiasis, edema, nocturnal enuresis
CI: use of other species (toxic), HTN, hypokalemia, coag do
AdvFX: long term use depletes thiamine, beriberi
Interactions: Avoid with hypokalemic drugs (diuretics, corticosteroids, cardiac glycosides, anti-arrythmics, pseudoephedrine, Glycyrrhiza
may antagonize warfarin
Eschscholzia californica
“california poppy”
Constituents: alkaloids
Actions: nervine, hypnotic, anti-spasmodic, anodyne
Indications: nerve related pain, neuraglia, sciatica, insomnia, anxiety, panic attacks
CI: pregnancy, lactation
AdvFX: addictive
Interactions: may potentiate MAOIs (phenelzine), SSRIs (fluoxetine)
Eucalyptus Globulus
Constituents: volatile oils, flavonoids, tannins
Actions: antimicrobial, counter-irritant, expectorant, antiperiodic
Indications: OA, RA, myalgia, strains, sprains, HA, URI, pharyngitis, tonsillitis, malaria (when cinchona is not indicated)
CI: hypotension, high dose EO, use over large areas of skin if pregnany
AdvFX: diarrhea, GI upset, cold skin, irregular breathing, mydriasis, depression, hypothyroidism
Interactions: none
Eupatorium Perfoliatum
“Boneset”
Constituents: sesquiterpene lactones, unsaturrated pyrrolizidine alkaloids, EOs, falvonoids, resins
Actions: diaphoretic, immune stimulant, anti-cattarhal
Indications: mild to moderate fever, infection, pain from cough, SOB, urinary frequency, GI spasm, bone pain
CI: high fever, internal use of isolated pyrrolizidine alkaloids, chronic use, hepatotoxicity, use with hepatotoxic drugs, ASTERACEA allergy
AdvFX: nausea, hepato veno-occlusive disease, hepatic failure
Interactions: synergistic with hepatotoxic drugs
Eupatorium purpureum
“Gravel root”
Constituents: unsaturated pyrrolizidine alkaloids, oleoresins
Actions: anti-lithic, diuretic
Indications: urolithiasis, dysuria, hematuria from prostatitis, gout
CI: internal use of pyrrolizidine alkaloids, chronic use, hepatotoxicity, use with hepatotoxic drugs, ASTERACEA ALLERGY
AdvFX: nausea, hepato veno-occlusive disease, hepatic failure
Interactions: synergist with hepatotoxic drugs
Euphrasia Officinalis (stricta)
“eye bright”
Constituents: iridoid glycosides, flavonoids, volatile oils, tannins
Actions: anti-inflammatory, anti allergic, anti-catarrhal, astringent, vasoconstrictor
Indications: opthalmias, allergic rhinitis, conjunctivitis (allergic), sinusitis, blepharitis, hordeolums, eye trauma
CI: none
AdvFX: confusion, HA, lacrimation, sneezing, insomnia, poyuria, sweating
Interactions: none