book 5 (stem cells) Flashcards
1
Q
describe the general features of stem cells
A
- self-renewal ability - it can divide via mitosis to produce new stem cells
- undifferentiated and unspecialized - cells do not have any cell-specific structures to carry out specific functions
- daughter cells have the ability to differentiate by turning on/off expression of specific genes
2
Q
describe the unique features and function of zygotic stem cells
A
- totipotent - they are able to differentiate into any cell type to form a whole organism, including the extra-embryonic tissues
- stem cells are derived from the cells of a morula
- functions for the development of whole organisms
3
Q
describe the features and function of embryonic stem cells
A
- pluripotent - they are able to differentiate into almost any cell type to form any organ or type of cells, except those of the extra-embryonic tissues
- stem cells are derived from the inner cell mass of the blastocyst
- functions to give rise to various organs in organisms, or multiple specialized cell types that make up the heart, lung, skin and other tissues in the developing foetus
4
Q
describe the features and function of adult stem cells
A
- multipotent - they are able to differentiate into a limited range of cell type to produce only cells of a single lineage
- derived from the specialized tissues eg myeloid and lymphoid stem cells are derived from the bone marrow
- it’s function of adult stem cells is to provide growth, tissue repair and tissue maintenance
- it can also generate a continuous supply or terminally differentiated cells through asymmetric division
5
Q
state the functions of myeloid and lymphoid stem cells
A
- myeloid stem cells differentiate into red blood cells, platelets as well as various types of white blood cells - monocytes, neutrophils, basophils
- lymphoid stem cells differentiate into 3 types of white blood cells - B and T lymphoid and natural killer cells, for the daily replacement of worn out blood cells from normal wear and tear, for fighting infections in diseases and from injuries