Bone Tumours

Question 1

What are the 4 main benign bone tumours?

Answer 1

Osteochondroma
Chondroma (enchondroma)
Osteoid osteoma
Chondroblastoma

Question 2

Describe osteochondroma

Answer 2

Cartilagenous bony projection on external surface of bone, usually near epiphyses, with marrow cavity continuous with original bone
Usually chondrocyte origin

Question 3

Describe chondroma/enchondroma

Answer 3

Hyaline cartilage tumour arising in the medullary cavity

Question 4

Which two developmental disorders are associated with chondroma?

Answer 4

Ollier’s disease and Maffuci syndrome

Question 5

Which has the greater risk of malignant transformation - Ollier’s disease or Mafucci syndrome?

Answer 5

Mafucci

Question 6

Describe osteoid osteoma

Answer 6

Osteoblastic tumour of neoplastic/infectious origin; appears as a lucent nidus with sclerotic bone

Question 7

List clinical features of osteoid osteoma

Answer 7

Swelling/tenderness
Males, children/young adults
Dull pain at night relieved by NSAID

Question 8

Describe chondroblastoma

Answer 8

Rare cartilagenous tumour within bone, usually epiphyses
Usually teenagers
“chicken-wire calcification”

Question 9

List the 3 main benign + locally aggressive tumours

Answer 9

Giant cell tumour
Osteoblastoma
Chordoma

Question 10

Describe giant cell tumours

Answer 10

Osteoclast-derived tumour of long bones, usually knee
Radiolucent with multinucleated cells
“soap-bubble” appearance on XR

Question 11

List the 3 main malignant bone tumours in order of most common - least common

Answer 11

Osteosarcoma
Chondrosarcoma
Ewing’s sarcoma

Question 12

Secondary bone tumours (metastatic) are more common than primary. True/False?

Answer 12

True