Bone Tumors Flashcards
Where does Osteoma form?
Surface of facial bones
Osteoma is associated with what syndrome?
Gardner Syndrome
FAP, retroperitoneal fibromatosis, osteomas
Osteoid Osteoma is benign tumor of what?
Osteoblasts
Where does Osteoid Osteoma form?
diaphysis of long bones in cortex (femur)
Compare osteoid Osteoma to osteoblastoma
Osteoblastoma is larger than 2cm, arises in vertebrae, and pain does not respond to aspirin. Osteoid Osteoma responds to aspirin
Most common benign tumor of bone?
Osteochondroma
where does osteochondroma form?
arises from lateral projection of growth plate (metaphysis) continuous with marrow space
Osteosarcoma is malignant proliferation of what?
osteoblasts
Osteosarcoma arises where?
metaphysis of long bones around knee
Osteosarcoma risk is increased in what 3 groups
familial retinoblastoma, Paget Disease of Bone, radiation exposure
sunburst appearance and lifting of periosteum (Codman Triangle)
Osteosarcoma
Histo of Osteosarcoma
Pleiomorphic cells that produce osteoid
only tumor on epiphysis
Giant cell Tumor, around the knee
Soap bubble appearance on X-Ray
Giant Cell Tumor
Ewing Sarcoma is derived from what?
neuroectoderm