Bone Pathology Flashcards
1
Q
blue sclera
opalescent teeth
A
osteogenesis imperfecta
2
Q
XR features:
- Wormian bone
- pulpal obliteration
- bowing
- fractures
A
osteogenesis imperfecta
3
Q
Wormian bone
A
osteogenesis imperfecta
cleiodocranial dysplasia
4
Q
Bisphosphate Tx
A
osteogenesis imperfecta
5
Q
collagen mutation
A
osteogenesis imperfecta
6
Q
Delayed tooth eruption
A
osteopetrosis
7
Q
missing, malformed, or hypoplastic clavicle
A
cleidocranial dysplasia
8
Q
unerupted succedaneous teeth
supernumery teeth
Wormian bone
open skull sutures
A
cleidocranial dysplasia
9
Q
- Unknown cause
- Always asymptomatic
- Non-vital or inflamed pulp
- Absence of deep restoration or caries
- Associated with root apex
A
idiopathic osteosclerosis
10
Q
- cannot make XR dg
- Aberrant bone regeneration after tooth extraction
- defect contains cellular hematopoetic and/or fatty marrow
- not a true neoplasm
A
Focal Osteoporotic Marrow Defect
11
Q
- Pain
- Mobile teeth
- Deviated mandible
- destruction of bone / replaced by vascular proliferation followed by fibrous fill
- Loss of lamina dura
- XR: Radiolucent, POORLY defined
A
Massive Osteolysis
12
Q
Mainly in mandible
A
- Central Giant Cell Granuloma
- Massive Osteolysis
- Focal Osteoporotic
- SBC
- ABC
- Ewing’s Sarcoma
13
Q
- Abnormal resorption and deposition of bone
- XR: “cotton wool” radiodensity, hypercementosis
- Simultaneously osteoblastic and osteoclastic activity
- convex vestibule, “My dentures no longer fit”, “I have a space b/w my teeth now”, “my hat no longer fits”
- Elevated serum alkaline phosphatase
- Tx: serum alkaline phosphatase, parathyroid hormone (PTH) antagonist
- Osteosarcoma 1%
A
Paget’s Dx
14
Q
Mainly in maxilla
A
Paget’s
Chondrosarcoma
15
Q
- May cross midline in mandible
- Children, young adults
- Agro: Rapid progression, no pain
- Non-agro: Slow progress; no pain
- usually anterior
- Associated with ABC and central odontogenic fibroma
- Identical to hyperparathyroidism brown tumors
- Multifocal lesions like cherubism
- XR: Radiolucent, well-defined
A
Central Giant Cell Granuloma
16
Q
Well-defined border
A
Central Giant Cell Granuloma
SBC
17
Q
Poorly-defined border
A
Massive osteolysis
18
Q
- Bilateral, symmetrical enlargement of posterior mandible
- Tooth displacement, failure to erupt
- cherub-like face
- Multinucleated giant cells
- XR: radiolucent, multilocular, expansile, bilateral
- Dg: Genetic tests
A
Cherubism
19
Q
Genetic, AD
A
cleidocranial dysplasia
osteogenesis imperfecta
cherubism
20
Q
Genetic AR
A
osteopetrosis
21
Q
Central Giant Cell Granuloma Rule out ____________
A
Hyperparathyroid
22
Q
A pseudocyst
A
Although fluid filled, It is NOT lined by EPITHELIUM
23
Q
Radiology:
- “cotton wool”
- hypercementosis
A
Paget’s
24
Q
Multinucleated Giant Cells
A
- Cherubism
- CGCG
- ABC
25
May move teeth
- ABC
- Massive osteolytis
- Cherubism
- Ewing's Sarcoma
26
- Blood filled spaces
- Multinucleated giant cells
- May move teeth
- radiolucent
- cortical expansion and thinning
- May be associated with CGCG or other BFOL
Aneurysmal Bone Cyst (ABC)
27
- Assymptomatic
- scalloping between teeth
- vital teeth
- radiolucent
- well-deliniated
- psuedocyst
- Trauma-Hemorrhage Theory // "Traumatic Bone Cyst"
Simple Bone Cyst (SBC)
28
Examples of pseudocysts
ABC
| SBC
29
Cross Midline
CGCG
30
CGCG Differential
- Hyperparathyroidism
- Cherubism
- ABC
31
XR: "Ground Glass" appearance
hyperparathyroid
| fibrous dysplasia
32
Neoplasm
osteosarcoma
33
XR: "sunburst", "sunray" appearance
osteosarcoma
34
Bone formation ABOVE the CEJ
osteosarcoma
35
SYMMETRICAL widening of PDL
osteosarcoma
36
what is happening in osteosarcoma?
Malignant mesenchymal cells producing bone
37
Tx for osteosarcoma
chemotherapy
irradiation
surgical excision
38
mimics an extraction that is just not healing properly the first 12 months
osteosarcoma
it takes the average dentist 12 months to dg
if you scoop out a tooth it can mimic epulous granulomatosum
39
location of osteosarcoma
posterior body and horizontal ramus of mandible
40
sarcoma
mesenchymal malignancy
41
telangiiactasia
blood vessels protruding
42
"Moth-eaten" borders
- chondrosarcoma
| - Malignant Jaw Tumor
43
root resorption
chondrosarcoma
44
PDL widening
- chondrosarcoma
- osteosarcoma
- Malignant Jaw Tumor
45
masquerades as infection
Ewing's Sarcoma
46
Neuroectoderal malignancy
Ewing's Sarcoma
47
Elevated ESR
Leukocytosis
Fever
Painful swelling
Ewing's Sarcoma
48
Paresthesia
- Ewing's Sarcoma
- Osteosarcoma
- Metastatic Tumors to the Jaws
49
Genetic Dg
Ewing's Sarcoma
50
Ewing's Sarcoma Tx
- multidrug chemotherapy + surgery
| - radiotherapy
51
"onion skin" bone
Ewing's Sarcoma
52
t(11:22)
Ewing's Sarcoma
53
2nd most common primary malignant bone tumor in pediatric pts
Ewings Sacoma
54
"numb chin syndrome"
| paresthesia
Metastatic Jaw Tumor
55
May mimic periodontitis
Metastatic Jaw Tumor
56
Most common is metastatic carcinoma from breast, lung, thyroid, prostate, and kidney cancers
Metastatic Jaw Tumor
