Bone Pathology Flashcards

1
Q

blue sclera

opalescent teeth

A

osteogenesis imperfecta

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2
Q

XR features:

  • Wormian bone
  • pulpal obliteration
  • bowing
  • fractures
A

osteogenesis imperfecta

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3
Q

Wormian bone

A

osteogenesis imperfecta

cleiodocranial dysplasia

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4
Q

Bisphosphate Tx

A

osteogenesis imperfecta

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5
Q

collagen mutation

A

osteogenesis imperfecta

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6
Q

Delayed tooth eruption

A

osteopetrosis

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7
Q

missing, malformed, or hypoplastic clavicle

A

cleidocranial dysplasia

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8
Q

unerupted succedaneous teeth
supernumery teeth
Wormian bone
open skull sutures

A

cleidocranial dysplasia

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9
Q
  • Unknown cause
  • Always asymptomatic
  • Non-vital or inflamed pulp
  • Absence of deep restoration or caries
  • Associated with root apex
A

idiopathic osteosclerosis

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10
Q
  • cannot make XR dg
  • Aberrant bone regeneration after tooth extraction
  • defect contains cellular hematopoetic and/or fatty marrow
  • not a true neoplasm
A

Focal Osteoporotic Marrow Defect

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11
Q
  • Pain
  • Mobile teeth
  • Deviated mandible
  • destruction of bone / replaced by vascular proliferation followed by fibrous fill
  • Loss of lamina dura
  • XR: Radiolucent, POORLY defined
A

Massive Osteolysis

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12
Q

Mainly in mandible

A
  • Central Giant Cell Granuloma
  • Massive Osteolysis
  • Focal Osteoporotic
  • SBC
  • ABC
  • Ewing’s Sarcoma
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13
Q
  • Abnormal resorption and deposition of bone
  • XR: “cotton wool” radiodensity, hypercementosis
  • Simultaneously osteoblastic and osteoclastic activity
  • convex vestibule, “My dentures no longer fit”, “I have a space b/w my teeth now”, “my hat no longer fits”
  • Elevated serum alkaline phosphatase
  • Tx: serum alkaline phosphatase, parathyroid hormone (PTH) antagonist
  • Osteosarcoma 1%
A

Paget’s Dx

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14
Q

Mainly in maxilla

A

Paget’s

Chondrosarcoma

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15
Q
  • May cross midline in mandible
  • Children, young adults
  • Agro: Rapid progression, no pain
  • Non-agro: Slow progress; no pain
  • usually anterior
  • Associated with ABC and central odontogenic fibroma
  • Identical to hyperparathyroidism brown tumors
  • Multifocal lesions like cherubism
  • XR: Radiolucent, well-defined
A

Central Giant Cell Granuloma

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16
Q

Well-defined border

A

Central Giant Cell Granuloma

SBC

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17
Q

Poorly-defined border

A

Massive osteolysis

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18
Q
  • Bilateral, symmetrical enlargement of posterior mandible
  • Tooth displacement, failure to erupt
  • cherub-like face
  • Multinucleated giant cells
  • XR: radiolucent, multilocular, expansile, bilateral
  • Dg: Genetic tests
A

Cherubism

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19
Q

Genetic, AD

A

cleidocranial dysplasia
osteogenesis imperfecta
cherubism

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20
Q

Genetic AR

A

osteopetrosis

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21
Q

Central Giant Cell Granuloma Rule out ____________

A

Hyperparathyroid

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22
Q

A pseudocyst

A

Although fluid filled, It is NOT lined by EPITHELIUM

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23
Q

Radiology:

  • “cotton wool”
  • hypercementosis
A

Paget’s

24
Q

Multinucleated Giant Cells

A
  • Cherubism
  • CGCG
  • ABC
25
Q

May move teeth

A
  • ABC
  • Massive osteolytis
  • Cherubism
  • Ewing’s Sarcoma
26
Q
  • Blood filled spaces
  • Multinucleated giant cells
  • May move teeth
  • radiolucent
  • cortical expansion and thinning
  • May be associated with CGCG or other BFOL
A

Aneurysmal Bone Cyst (ABC)

27
Q
  • Assymptomatic
  • scalloping between teeth
  • vital teeth
  • radiolucent
  • well-deliniated
  • psuedocyst
  • Trauma-Hemorrhage Theory // “Traumatic Bone Cyst”
A

Simple Bone Cyst (SBC)

28
Q

Examples of pseudocysts

A

ABC

SBC

29
Q

Cross Midline

A

CGCG

30
Q

CGCG Differential

A
  • Hyperparathyroidism
  • Cherubism
  • ABC
31
Q

XR: “Ground Glass” appearance

A

hyperparathyroid

fibrous dysplasia

32
Q

Neoplasm

A

osteosarcoma

33
Q

XR: “sunburst”, “sunray” appearance

A

osteosarcoma

34
Q

Bone formation ABOVE the CEJ

A

osteosarcoma

35
Q

SYMMETRICAL widening of PDL

A

osteosarcoma

36
Q

what is happening in osteosarcoma?

A

Malignant mesenchymal cells producing bone

37
Q

Tx for osteosarcoma

A

chemotherapy
irradiation
surgical excision

38
Q

mimics an extraction that is just not healing properly the first 12 months

A

osteosarcoma

it takes the average dentist 12 months to dg

if you scoop out a tooth it can mimic epulous granulomatosum

39
Q

location of osteosarcoma

A

posterior body and horizontal ramus of mandible

40
Q

sarcoma

A

mesenchymal malignancy

41
Q

telangiiactasia

A

blood vessels protruding

42
Q

“Moth-eaten” borders

A
  • chondrosarcoma

- Malignant Jaw Tumor

43
Q

root resorption

A

chondrosarcoma

44
Q

PDL widening

A
  • chondrosarcoma
  • osteosarcoma
  • Malignant Jaw Tumor
45
Q

masquerades as infection

A

Ewing’s Sarcoma

46
Q

Neuroectoderal malignancy

A

Ewing’s Sarcoma

47
Q

Elevated ESR
Leukocytosis
Fever
Painful swelling

A

Ewing’s Sarcoma

48
Q

Paresthesia

A
  • Ewing’s Sarcoma
  • Osteosarcoma
  • Metastatic Tumors to the Jaws
49
Q

Genetic Dg

A

Ewing’s Sarcoma

50
Q

Ewing’s Sarcoma Tx

A
  • multidrug chemotherapy + surgery

- radiotherapy

51
Q

“onion skin” bone

A

Ewing’s Sarcoma

52
Q

t(11:22)

A

Ewing’s Sarcoma

53
Q

2nd most common primary malignant bone tumor in pediatric pts

A

Ewings Sacoma

54
Q

“numb chin syndrome”

paresthesia

A

Metastatic Jaw Tumor

55
Q

May mimic periodontitis

A

Metastatic Jaw Tumor

56
Q

Most common is metastatic carcinoma from breast, lung, thyroid, prostate, and kidney cancers

A

Metastatic Jaw Tumor