Bone Formation

Question 0

What happens in the zone of resorption?

Answer 0

CT and small BV invade
Calcified spicules are formed between dying chondrocytes
Bone is formed by osteoblasts on spicules

Question 1

What are the layers of long bone formation?

Answer 1

Resorption
Calcified cartilage
Hypertrophy 
Proliferation
Reserve cartilage

Question 2

What happens in the calcified cartilage zone?

Answer 2

Cells enlarge

Matrix calcified

Question 3

What happens in the zone of hypertrophy?

Answer 3

Cells enlarge greatly

Matrix is compressed into linear bands

Question 4

What happens in the zone of proliferation?

Answer 4

Cells divide to form columns

Continue to secrete matrix

Question 5

What happens in the zone of reserve cartilage?

Answer 5

Not a lot

Question 6

What happens in the haematoma during bone fracture?

Answer 6

BV broken

Dead bone cells removed by macrophages and osteoclasts

Question 7

What happens in the fibrocartilaginous callus?

Answer 7

New BV in
Pro callus of granulation tissue
Type I then type II collagen
Hyaline sleeve
Osteoblasts from perichondrium and endosteum invade

Question 8

What happens in the bony callus of bone fracture?

Answer 8

Trabeculae appear

Intramembranous and endochondral ossification

Question 9

What happens during bone remodelling of fracture site?

Answer 9

Cancellous to compact bone

Question 10

What are the stages of fracture repair?

Answer 10

Haematoma
Fibrocartilaginous callus
Bony callus
Bone remodelling