Bone diseases Flashcards

1
Q

Garre’s sclerosing osteomyelitis is also called:

A

1.Proliferative periostitis
2.Osteomyelitis with proliferative periostitis
3.Periostitis ossificans

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2
Q

Histopathologic picture of proliferative periostitis

A

1.Trabeculae of woven bone: arranged in parallel rows or retiform (interconnecting meshwork), often perpendicular to the surface.
2.Intertrabecular loose, vascular, uninflammed fibrous connective tissue.

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3
Q
A

Proliferative periostitis

Histopathologic picture includes:

1.Trabeculae of woven bone: arranged in parallel rows or retiform (interconnecting meshwork), often perpendicular to the surface.

2.Intertrabecular loose, vascular, uninflammed fibrous connective tissue.

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4
Q
A

Proliferative periostitis

Histopathologic picture includes:

1.Trabeculae of woven bone: arranged in parallel rows or retiform (interconnecting meshwork), often perpendicular to the surface.

2.Intertrabecular loose, vascular, uninflammed fibrous connective tissue.

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5
Q
A

Proliferative periostitis

Histopathologic picture includes:

1.Trabeculae of woven bone: arranged in parallel rows or retiform (interconnecting meshwork), often perpendicular to the surface.

2.Intertrabecular loose, vascular, uninflammed fibrous connective tissue.

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6
Q
A

Proliferative periostitis

Histopathologic picture includes:

1.Trabeculae of woven bone: arranged in parallel rows or retiform (interconnecting meshwork), often perpendicular to the surface.

2.Intertrabecular loose, vascular, uninflammed fibrous connective tissue.

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7
Q

Proliferative periostitis - differential diagnosis

A

1.Osteogenic sarcoma
2.Ewing sarcoma
3.Langerhans cell histiocytosis
4.Ossifying fibroma

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8
Q

Proliferative periostitis - Age

A

Children and young adults.
Average age: 13

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9
Q

Proliferative periostitis - clinical presentation

A

Non-painful swelling
Unilateral
Usually in the posterior mandible
Hard consistency

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10
Q

Proliferative periostitis - radiographic picture

A

Focal parallel radiopacities extending from the cortical surface
“Onion skin” appearance
Radiolucent area between original cortex and the newly formed bone layers

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11
Q

Proliferative periostitis - locations frequencies

A
  1. Inferior border of mandible
  2. Buccal cortex of mandible
  3. Lingual cortex of mandible
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12
Q

Proliferative periostitis - number of bony layers

A

1-12

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13
Q

Proliferative periostitis etiology

A

Reactive lesion:
1. Periapical inflammation
2. Periodontal inflammation
3. Buccal bifurcation cyst

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14
Q

Proliferative periostitis - time of bone remodeling

A

6-12 months after removal of cause (e.g. RCT)

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15
Q

Primary chronic ostemyelitis (PCO) and diffuse sclerosing osteomyelitis (DSO): what is the etiology difference?

A

PCO: no association with dental infection; probably immunologic etiology.

DSO: associated with chronic dental infection.

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16
Q

Primary chronic ostemyelitis (PCO) and diffuse sclerosing osteomyelitis (DSO): what is the difference in the clinical presentation?

A

PCO: pain, swelling
DSO: no pain and swelling

17
Q

PCO: clinical picture

A

Pain
Swelling (bone expansion) Facial deformity
Trismus
Lymphadenopathy
Loss of sensation

The nature of the disease is cylic: periodic episodes of flares and remissions

18
Q

Primary chronic osteomyelitis and chronic suppurative osteomyelitis: what are the differences in the clinical presentation?

A

PCO:

NO fever
NO pus discharge
NO fistula formation
NO sequestration of bone

CSO: the above signs are present.

19
Q

Primary chronic ostemyelitis (PCO) and diffuse sclerosing osteomyelitis (DSO): what is the difference in the radiographic presentation?

A

PCO:
radiographic features can include the following:
1.RL lesion (osteolysis)
2.Mixed RL-RO lesion
3.RO lesion (osteosclerosis)
4.Periosteal thickening
5.External bone resorption

DSO:
Diffuse radiopacity

20
Q

Primary chronic ostemyelitis (PCO): therapeutic management

A

Medication:
Biphosphanates
NSAIDs
Corticosteroids
Pamidronate
Denosumab
Calcitonin
Tumor necrosis factor-a antagonists
Hyperbaric oxygen
Decortication

21
Q

Chronic sclerosing osteomyelitis: therapeutic management

A

Treatment of removal of infected tooth

22
Q

What is CRMO?

A

Chronic Recurrent Multifocal Osteomyelitis

Shows PCO in extra-gnathic bones

23
Q

What is SAPHO?

A

Sinovitis, Acne, Putulosis, Hyperostosis, Osteitis

Shows PCO in extra-gnathic bones

24
Q

Chronic tendoperiostitis

A

A variant of PCO, where parafunctional, overuse of masticatory muscles exist