bone and new markers Flashcards

1
Q

what is the purpose of bone?

A

stability
strength
movement
storage

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2
Q

what is the structure of cortical bone?

A

Hard and is the outer layer of bone

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3
Q

what is the structure of trabecular bone?

A

spongy and the inner layer of bone

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4
Q

what is the composition of bone

A

it is made up of cells

  • bone forming cells
  • bone resorbing cells
  • bone co-ordinating cells
Extracellular
Organic matrix - 30%
- mainly collagen (osteoid)
- ground substance 
Inorganic components - 70%
- hydroxyapatite (calcium and phosphate)
- minerals (magnesium, sodium, potassium)
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5
Q

what produces the extracellular matrix?

A

produced by osteoblasts

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6
Q

what is the role of the osteoblasts?

A
  • makes hormones
  • communicates with other bone cells
  • mineralise organic matrix
  • makes osteoids
  • become osteocytes
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7
Q

what is the role of osteoclasts

A

to breakdown old bone

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8
Q

how often is the adult skeleton replaced

A

every 10 years

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