bone and joints Flashcards
History of sore joints. Key questions to history?
- Which joints?
- Morning stiffness?
- night pain?
- joint swellings?
- associated with psoriasis, inflammatory bowel disease or other autoimmune disease.
- extraarticular features.
Clinical features of osteoarthritis?
- Bony tenderness
- Bony enlargement
- crepitus
- deformity
- lack of inflammatory features; boggy, joint swelling, or prolonged morning stiffness.
Locations:
- Hands: DIP and PIP joints, base of thumbs
- Hips
- Knees.
Other differentials of multiple joint pains?
- Non articular - bursitis
- Polyarticular
- Crystal arthropathies - gout and pseudo gout
- inflammatory arthropathies - rheumatoid arthritis, psoriatic arthritis
- Wide spread pain
- fibromyalgia
- polymyalgia rheumatoica.
Features of inflammatory arthritis?
- Pain at night
- Pain in the morning
- Prolonged stiffness >1 hour
- intermittent joint swelling
Investigations for suspected inflammatory arthritis?
- inflammatory markers: ESR or CRP
- Autoimmune serology: Rheumatoid factor, anti-CCP
- Imaging; x-ray and ultrasound
- Fluid biopsy
Osteoarthritis manamgenet:
Non-pharm
- Weight loss - dietitian referral
- Exercise - muscle strengthening
- Educations -
- Occupational therapy - splints, walking aids.
Pharma:
- Paracetamol
- NSAIDS
- PPI - in conjuction with NSAIDs
- Opioids
- Corticosteroid injections - minimal evidence -
- Hyaluronic acid - minimal evidence
- Topical NSAIDs and capsaicin cream -
What therapy is particular helpful in hand OA?
Topical naiads and capsaicin cream
Complementary or alternative therapy useful in OA?
- Chondroitin sulphate
- Glucosamine supphate
limited evidence in: every other complementary:
- Acupuncture
- Fish oil
- avocado
- greenlipped mussels, giner, indian frankincense, phytodolor, pine bark extracts, chinese herbal medicine, turmeric, vitamin A, C, E, B.
Indications for surgery in OA?
- significant functional disability and pain despite conservative measures.
What are features that would suggest inflammatory back pain? i.e. spondylar arthropathies
- morning stiffness >30min
- improvement
- awaking in the second half of the night
- alternating buttock pain
Ddx of spondyloarthritides
- ankylosing spondylitis
- psoriatic arthritis
- reactive arthritis
- arthritis of inflammatory bowel
- juvenile spondylar arthropathiees
Investigations of spondyloathritides?
- X-ray - AP pelvic, and lumbar spine X-ray
- HLA - B27
- inflammatory markers - ESR and CRP
- Renal and LFTs
How to diagnose Ankylosing Spondylitis
Sacroillitis on conventional X-ray +
History of inflammatory back pain
Non-radiographic axial SpA: lacking radiographic changes, but with history features - may warrant MRI spine
Management of Ankylosing Spondylitis?
NON-PHARM:
- Exercise
- Spinal stretching program
- Physio
- Smoking changes
PHARM:
- NSAIDs
- DMARDs
What DMARDS are used in AK?
- Sulphasalazine and methotrexate.