Bone Flashcards

1
Q

Function of bone (5)

A
  • support
  • movement
  • protection
  • calcium homeostasis
  • storage
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

haematopoiesis

A

formation of blood cellular components

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

haematopoiesis location

A

takes place in bone marrow. specifically red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Types of bone

A
  • sutural
  • pneumatised
  • flat
  • short
  • long
  • irregular
  • sesamoid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

sutural bones

A
  • Small, flat, oddly shaped
  • Found between flat bones of skull in the suture line
  • Develop from separate centres of ossification
  • Type of flat bone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Flat bones

A
  • Contain thin, roughly parallel surfaces of compact bone
  • Resembles spongy bone sandwich
  • Strong but light
  • Roof of the skull, sternum, ribs and scapulae
  • Provide protection for soft tissues and extensive surface area for attachment of skeletal muscles
  • Thick layers of compact bone = internal and external tables
    Layer of spongy bone between = diploë
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pneumatised bones

A
  • hollow
  • contain numerous air pockets
  • ethmoid (nose)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

short bones

A
  • Boxlike
  • External surfaces covered by compact bone
  • Interior contains spongy bone
  • Carpal bones (wrists)
  • Tarsal bones (ankles)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

long bones

A
  • Long and slender - Contain a diaphysis, 2 metaphysis, 2 epiphyses and a medullary cavity
  • Found in upper and lower limbs
    e.g. humerus, radius, ulna, femur, tibia, fibula
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

irregular bones

A
  • Complex shapes with short, flat, notched or ridged surfaces
  • Varied internal structure
  • Vertebrae, bones in the skull
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

sesamoid bones

A
  • Small, round and flat
  • Develop inside tendons
  • Mostly located in joints at the knee/hands/feet
  • kneecaps
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

order of sections of bone from top to centre

A

epiphysis -> metaphysis -> diaphysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

articular surface

A

located on epiphysis, provides smooth lubricated surface for articulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

order of sections of bone from outside in

A

articular cartilage -> periosteum -> compact bone -> endosteum -> trabecular bone -> medullary cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

periosteum

A
  • Is a tough, vascularised fibrous sheath
  • Superficially covers parts of the bone where there is no cartilage
  • Nourishes and protects the bone
  • Forms an attachment site for ligaments and tendons
  • Superficial layer high on fibres
  • Deep layers have osteogenic (bone forming) cells for bone repair
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Endosteum

A
  • A thin membrane that lines medullary cavity
  • Single layer of bone forming (osteoprogenitor) cells
  • Sparse matrix of collagen fibres
17
Q

medullary cavity

A
  • a hollow cavity containing bone marrow
  • minimises the weight of the bone where it is least needed
18
Q

organic matrix of bone

A
  • 35%
  • type 1 collagen
  • Proteoglycans and glycosaminoglycan
  • Glycoproteins: osteonectin and osteocalcin
19
Q

inorganic matrix of bone

A
  • 65%
  • calcium phosphate -> hydroxypatite
  • hardness, compressive strength
20
Q

osteocyte

A

mature bone cell that maintains and monitors the protein and mineral content of the matrix, signals stress

21
Q

osteoprogenitor cell

A

a stem cell that differentiates from mesenchyme and divisions of which produces osteoblasts

22
Q

osteoblast

A

immature bone cell that secretes organic components of matrix in the process of osteogenesis

23
Q

osteoclast

A

a large, multinucleate cell derived from monocytes which secretes acids and enzymes to dissolve bone matrix in the process of osteolysis

24
Q

woven bone

A
  • Immature bone
  • Random arrangement of collagen fibres
  • First formed during foetal development or repair of fracture
  • Remodelled into lamellar bone
25
Q

lamellar bone

A
  • Mature bone - virtually all bone in healthy adults
  • Either compact or spongy
  • Concentric bands of collagen
  • Fibres are oriented in one direction in each layer, but each layer is in different directions -> increase in strength
26
Q

Osteon

A
  • functional unit consisting of concentric lamellae
    contains:
  • lacunae
  • canaliculi
  • haversian canals
  • Volkmann canals
27
Q

lacunae

A

spaces between concentric lamellae

27
Q

canaliculi

A

small extracellular fluid filled channels radiating from lacunae, link lacunae

28
Q

haversian canals

A
  • central canals
  • neurovascular
29
Q

Volkmann canals

A
  • perforating canals
  • provide channels for neurovascular structures between adjacent osteons, periosteum and marrow`
30
Q

spongy bone

A
  • Also known as cancellous or trabecular bone
  • Composed of a latticework of thin plates of bone called trabeculae, oriented along lines of stress
  • Spaces in between the struts are filled with red marrow
  • It is found in the ends of long bones with inside flat bones such as hip bones, sternum and ribs
  • Although the concentric lamellae within resembles that of an osteon, there are no true osteons in spongy bone
31
Q

concentric lamellae

A

tubes of different size fitting inside each other to make an osteon

32
Q

2 methods of bone formation

A
  1. intramembranous ossification
  2. endochondral ossification
33
Q

intramembranous ossification

A
  • Ossification within a membrane
  • Special cells secrete a protein matrix that later mineralises
  • Primarily flat and irregular bones (facial bones, skull, clavicle)
34
Q

endochondral ossification

A
  • The replacement of hyaline cartilage by bone
  • Mesenchyme turns into cartilage that is later replaced by bone
  • Majority of bones in skeletal system
  • Normally associated with growth in length
35
Q
A