Bolognia Flashcards

1
Q

civatte bodies

A

dead basal keratinocytes

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2
Q

viruses associated with lichen planus

A

hep c, hhv 6/7, hsv/vzv

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3
Q

drugs associated with lichen planus

A

quinidine, antimalarials, ace inhibitors, beta blockers

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4
Q

direct immunofluorescence findings of lichen planus

A

shaggy fibrinogen

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5
Q

treatment of lichen planus

A

topical cs, light therapy, acitretin, mycophenolate

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6
Q

graham little syndrome findings

A

keratosis pilaris, non scarring alopecia of axilla and pubic region, scarring alopecia of scalp

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7
Q

what are cathelicidins and defensins

A

antimicrobial peptides

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8
Q

cathelicidin and defensin levels in:

a) psoriasis
b) atopic dermatitis

A

pso- increased

ad- decreased

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9
Q

TLRs work through which receptor?

and what is the exception?

A

Myd88

exception- TLR3

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10
Q

which TLR in acne?

A

TLR2

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11
Q

which TLR targeted by imiquimod?

A

TLR7

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12
Q

which TLR detects viral dsRNA?

A

TLR3

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13
Q

complement levels in lupus

A

decreased

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14
Q

which complement does opsonization?

A

c3b

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15
Q

which complement does membrane attack complex

A

C5a, C6-C9

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16
Q

which complement is anaphylatoxin

A

C3, C5a

17
Q

which complement attract PMNs?

A

C5a