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Physiology Revision > Body Fluid, Plasma Membrane > Flashcards

Body Fluid, Plasma Membrane Flashcards

1
Q

Total body water varies with

A

Age
Degree of obesity
Gender
Disease

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2
Q

Least hydrated tissue in the body

A

Adipose tissue

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3
Q

Total body water (%) of adults

A

60% of body weight

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4
Q

Total body water (%) in infants

A

73% of body weight

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5
Q

Total body water (%) in old age

A

45% of body weight

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6
Q

TBW (%) in men

A

55-60%

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7
Q

TBW (%) in young women

A

45-50%

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8
Q

% of water in a fat-free tissue is constant at

A

73%

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9
Q

Ions in ICF

A

K
Mg
Phosphate and organic anions
Proteins

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10
Q

Ions in ECF

A

Na
Cl
Bicarbonate

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11
Q

What is the only compartment that declines with age

A

Interstitial fluid

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12
Q

Examples of transcellular fluid

A

Aqueous humor
CSF
GIT fluids
Serous fluids
Joint fluid
Pericardial and peritoneal fluid

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13
Q

What fluid is contained within epithelial lined spaces and is outside of the normal compartments

A

Transcellular fluid

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14
Q

TBW is measured with

A

Tritium oxide and deuterium oxide

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15
Q

ECF volume is measured with

A

Insulin
Mannitol
Sucrose
Radioactive isotopes

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16
Q

Plasma volume is measured by

A

Risa

17
Q

Which volume cannot be measured directly

A

Interstitial volume

18
Q

Difference between ECF and plasma volume

A

Interstitial volume

19
Q

Difference between TBW and ECF

A

ICF

20
Q

Contains both ECF and ICF

A

Blood volume

21
Q

If plasma volume is 3 liters and hematocrit is 0.40, total blood volume would be calculated as

A

5 liters
Total blood volume = Plasma volume/1-hematocrit

22
Q

What are the major classes of lipid molecules

A

Glycolipids
Cholesterol
Phospholipids

23
Q

What is the main component of the lipid bilayer

A

Phospholipids

24
Q

The phospholipid membrane is held by what forces

A

Non-covalent interactions of hydrophobic tails

25
Q

What are the four major groups of phospholipids which make up the plasma membrane

A

Phosphatidylcholine
Phosphatidylethanolamine
Phosphatidylserine
Sphingomyeline
Phosphatidylinositols are present in small quantities

26
Q

What keeps the membrane fluid at temperatures conducive to life

A

The right ratio of saturated to unsaturated fatty acids

27
Q

Membrane proteins are classified into

A

Integral and peripheral proteins

28
Q

They are integral proteins which are only embedded into one side of the cell membrane

A

Monotopic proteins

29
Q

They are integral proteins which have hydrophobic regions that completely span the hydrophobic interior of the membrane

A

Transmembrane proteins

30
Q

Examples of integral proteins

A

Transmembrane proteins
Monotopic proteins

31
Q

What membrane protein binds to lipids or other integral proteins

A

Peripheral proteins

32
Q

They are not embedded in the lipid bilayer

A

Peripheral proteins

33
Q

Functions of plasma membrane proteins

A

Channels
Carrier proteins
Receptors
Enzymes
CAM - desmosomes, gap junctions, tight junctions
Antigens
Surface recognition
Cytoskeleton contact

34
Q

Is the plasma membrane symmetrical

A

No it is asymmetrical
Meaning the cell membrane tends to have different composition on one side of the membrane than on the other side

The apical, lateral and basal surfaces of the cell membrane having different functions

35
Q

Contents of the cell membrane

A

Carbohydrates
Proteins
Phospholipids

36
Q

What can be used to remove peripheral proteins

A

Alkaline solutions or high salt

37
Q

Carbohydrates covalently binding to lipids are called

A

Glycolipids

38
Q

True or false
Carbohydrates bind with proteins
They also bind with lipids

A

T

39
Q

Loose coat on the membrane formed by carbohydrates are called

A

Glycocalyx

Physiology Revision (1 decks)

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