BoardVitals Flashcards
Best goal for rhinoplasty in Asian nose that is ptotic, bulbous, underprojected, and broad?
Tip projection via columellar strut placement
What do ameleoblastomas arise from?
Tooth enamel precursor cells
Linear transposition flaps have a tendency towards what kind of deformity?
Trap-door deformity (due to underlying scar formation)
What imaging should be obtained in the setting of a post-op chyle leak?
CXR to rule out concurrent chylothorax
What medication should be given when a patient has a moderate output chyle leak?
Octreotide (100 mcg subq TID) to reduce splanchnic blood flow and decrease GI chyle production
What % of chyle leaks occur on the right side?
25%: inturruption of the right lymphatic duct on its path to the right subclavian vein
What cranial nerves are most often impacted by a jugular paraganglionoma?
CN IX-XII
What is Vernet syndrome?
Paralysis of CN 9, 10, 11
What is Collet-Sicard syndrome?
Paralysis of CN 9, 10, 11, 12
In what direction will the internal and external carotid arteries be displaced by a carotid paraganglionoma?
Carotid body tumors splay the internal and external carotids, displacing the external anteriorly and the internal posteriorly
What kind of paraganglionoma would displace the external and internal carotids anterior and medial?
Vagal paraganglionoma
What is the basic procedure of an anterior cricoid split?
Incision of the anterior cricoid and the first two tracheal rings
Stenting with an ETT for 12-14 days
What are the criteria for performing anterior cricoid split in an infant?
Failure to extubate on at least 2 occasions
Infant weight > 1500 g
No assisted ventilation for at least 10 days
Minimal supplemental O2 requirements
Absence of CHF
Absence of URI
No need for antihypertensives
What makes anterior cricoid split superior to balloon dilation for long term extubation in subglottic stenosis?
Balloon dilation can provide temporary relief but needs to be repeated frequently
Which site of paraganglionomas has the highest risk of malignancy?
Orbital and laryngeal (25%)
Vagal (10%)
Jugular and tympanic (5%)
Carotid body (3-6%)
Is acute mastoiditis associated with smoke exposure?
No
What joins to form the internal jugular vein? Where does it form?
Sigmoid sinus and common facial vein
Starts in the posterior compartment of the jugular foramen at the base of the skull
What joins to form the external jugular vein? Where does it form?
Posterior facial and posterior auricular
Forms in the parotid gland at the level of the angle of the mandible
What degree of subglottic extension is a contraindication to a vertical partial laryngectomy?
> 10 mm anteriorly
>5 mm posteriorly
What does electrocochleography measure?
Neuroelectric events generated by the cochlea and auditory nerve in response to acoustic stimulation
What does an ABR assess?
The auditory pathway function in response to auditory stimuli
What is the level at which a patient is aware of a speech signal 50% of the time?
Speech detection threshold
What does directional preponderance express?
How the amount of right beating nystagmus compares with left beating nystagmus in caloric testing
What is the Brent and Kuhn criteria for the dx of allergic fungal sinusitis?
- Eosinophilic mucin (charcot-leyden crystals)
- Noninvasive fungal hyphae
- Nasal polyposis
- Characteristic radiographic findings
- Type 1 hypersensitivity by hx, skin test, or serology
What does CT and MRI show in allergic funcal sinusitis?
CT: rim of hypointensity with hyperdense central material (allergic mucin), speckled areas of increased attenuation due to ferromagnetic fungal elements
MRI: peripheral hyperintensity with central hypointensity on both T1 and T2, central void on T2
What should be done when an acute otitis media is found prior to cochlear implant placement
This is a contraindication to placement of the CI, T tubes should be placed and CI should be deferred until the pt is clear of infection for two weeks
What should be done if a serous otitis media is noted before placement of a cochlear implant?
Middle ear irrigation
Use of topical antibiotic drops
Post-op antibiotic therapy
What AHI corresponds to mild, moderate, and severe AHI in adults?
Mild: 5-15/hr
Moderate: 15-30/hr
Severe: >30/hr
What is MEN IIb characterized by?
Medullary thyroid carcinoma
Mucosal neuromas
Pheochromocytoma
Marfinoid habitus
What is MEN I characterizes by?
Pituitary tumors
Parathyroid hyperplasia
Pancreatic tumors
What gene is associated with MEN IIa and IIb?
RET protooncogene
What is MEN IIa characterized by?
Parathyroid hyperplasia
Pheochromocytoma
Medullary thyroid carcinoma
What air-bone gap cut-offs do the following tuning fork frequencies correspond to?
256 Hz: 15 dB or more
512 Hz: 25 dB or more
1024 Hz: 35 dB or more
What is the IM dose of epinephrine that should be given to an adult for anaphylaxis?
0.3-0.5 mL of 1:1000 solution
What is the IM dose of epinephrine that should be given to a child for anaphylaxis?
0.01-0.03mg/kg or 0.1-0.3 mL of 1:1000 solution
In what percent of cases is tracheomalacia noted in substernal multi-nodular goiters?
3% of cases
What is the scutum?
Lateral wall of the epitympanum
Wedge shaped piece of bone
What is blunting of the scutum on CT scan indicative of?
Cholesteatoma
What is the area between the chorda tympani and the facial nerve?
Facial recess
What space is bordered superiorly by the ponticulus and inferiorly by the subiculum?
Sinus tympani
What structure takes up the largest portion of the medial wall of the mesotympanum?
Promontory
What forms the rounded hollow prominence of the promontory?
first turn of the cochlea
Orphan annie eyes after thyroid biopsy suggests:
Papillary thyroid carcinoma
What is the treatment modality of choice for thyroid lymphoma?
Chemo and radiation, not surgery
Are most thyroid lymphomas Hodgkins or non-Hodgkins?
Non-Hodgkins
What is the typical patient for a thyroid lymphoma?
Female >70 yo with a history of Hashimotos thyroiditis
**rapidly enlarging neck mass causing respiratory difficulty
What plays a significant role in the formation of recurrnet subglottic stenosis after balloon dilation in children?
Uncontrolled GERD
What is the treatment for postinflammatory hyperpigmentation as a complication of skin resurfacing procedures with higher Fitzpatrick grades?
Hydroquinone (tyrosinase inhibitor, inhibits conversion of tyrosine to DOPA in melanocytes)
Sun block
Exfoliant
What is the treatment of adductor vs abductor spasmotic dysphonia?
Botox injection to the:
Adductor: vocalis muscle
Abductor: posterior cricoarytenoid
What are the four kinds of frontal cells as described by Bent and Kuhn
Type 1: single frontal ethmoidal cell above the agger nasi
Type 2: multiple cells above the agger nasi
Type 3: cells pneumatize into the floor of the frontal sinus
Type 4: Isolated frontal ethmoidal cells contained entirely in the frontal sinus
What are agger nasi cells?
The most anterior ethmoidal air cells lying anterolateral and inferior to the frontoethmoidal recess and anterior and above the attachment of the middle turbinate
Located within the lacrimal bone
What is found immidiately behind the poster-medial wall of the agger nasi cell?
Drainage of the frontal sinus
What is the most common causative organism of Lemierre syndrome?
Fusobacterium necrophorum
What is the best antibiotic for tx of Lemierres syndrome?
Metronidazole (prolonged course up to 6 weeks)
What typically proceeds Lemierres syndrome?
Peritonsillar abscess: infection spreads to the adjacent internal jugular vein, creating septic thrombophelbitis
What forms the vidian nerve?
What fibers does it contain?
Junction of the greater petrosal and the deep petrosal nerves
Parasympathetic and sympathetic fibers, esp parasympathetic fibers supplying the lacrimal gland
What is an indication for vidian neurectomy?
Crocodile tears–tearing while eating
Vidian nerve carries parasympathetic fibers to the lacrimal gland
What is the most common manifestation of MEN2A?
Medullary thyroid carcinoma
Pheo in 70%
Hyperparathyroidism in 20-35%
What is the key difference between the Abbe and Estlander flaps for lip reconstruction?
Estlander includes the oral commisure
What is the indication for a Karapandzic flap?
Reconstruction of a large lower lip defect of more than half and up to 2/3 of the lip
What is the indication for a Gilles flap?
Reconstruction of large lower lip defects of greater than 2/3 of the lip tissue
What part of a flow volume loop will be altered in the setting of a variable extrathoracic lesion like fixed vocal folds?
Flattening of the inspiratory (bottom) loop
1 mg of protamine negates the effects of ___ units of unfractionated heparin
100 units
What is a central megaincisor a pathognomic feature of?
Congnital pyriform aperature stenosis
What kind of bacterium causes a violacious hue overlying a subacute neck mass in a child
Atypical mycobacterium
56% Mycobacterium acium intracellulare
29% Mycobacterium tuberculosis
What layers does blood collect between in an auricular hematoma?
Perichondrium and cartilage
In an auricular hematoma, fibroneocartilage begins to form __ days after injury, resulting in a _____ deformity
7-10
Cauliflower
What nerve provides sensory innervation to the superior pinna, helix, and anti-helix
Auriculotemporal nerve
When should auricular hematoma pts be seen following bolster placement?
24-48 hr
Should a load bearing or load sharing plate be used in an edentulous, atrophic mandible?
Load bearing–load sharing requires significant bone to bone contact and the strength to share the load
What is the general MOA of methimazole and propylthiouracil?
Inhibition of TH synthesis by inhibiting oxidation and organification of iodine
PTU also disrupts conversion of T4 to T3
Which anti-thyroid med is safe in the first semester of pregnancy?
Propylthiourail
What is the feared side effect of anti thyroid drugs?
Agranulocytosis (occurs in 0.2% or less of pts)
How does TNM staging for mucosa melanoma differ from that of cutaneous melanoma?
No T1 or T2, starts at T3 because mucosal has a worse prognosis
N0 is no LN mets, N1 is regional LN mets
What is the most common presenting sx of nasopharyngeal carcinoma?
Neck mass 75%
Nasal sx (obstruction, epistaxis) 73%
Impaired hearing 19%
What changes occur with the following with aging?
- Epidermis
- Dermis
- Elastin
- Melanocyte count
- Dermal connective tissue
- Epidermis thins
- Dermis atrophies
- Elastin decreases
- Fewer melanocytes
- Increase in the ground substance component of dermal CT
What is the course of parasympathetic innervation to the parotid gland from the inferior salivatory nucleus?
Inferior salivatory nucleus (medulla) Glossopharyngeal nerve Jacobson's nerve Tympanic plexus Lesser petrosal nerve Otic ganglion Joins post-ganglionic fibers in the auriculotemporal nerve of V3 division
What type of antibiotic is a contraindication to botox injection?
Aminoglycosides: potentiation of neuromuscular blockade
What are CD 19, 20, and 22 markers of?
B lymphocytes
What at CD 2, 3, 4, and 8 markers of
T lymphocytes
What are CD 16 and 56 markers of?
NK cells
What is CD 69 a marker of?
Eosinophils
What is the distance from:
- anterior lacrimal crest to the anterior ethmoid artery
- anterior lacrimal crest to the posterior ethmoid artery
- anterior lacrimal crest of the optic foramen
24
36
42
What specific area is more likely to get a subglottic hemangioma?
Posterior left subglottis
How often are subglottic hemangiomas associated with skin hemangiomas?
50% of the time
Pleomorphic ademomas comprise about __% of all parotid tumors
65%
How often are Warthin tumors bilateral?
5-7.5% (more commonly bilateral than pleomorphic adenomas)
What is the primary treatment of fungal rhinosinusitis 2/2 aspergillus? Mucormycosis?
IV voriconozole
IV amphotericin
What organism causes cat scratch fever?
Bartonella henselae
What is the most appropriate treatment for cat scratch fever?
Azithromycin 5 days
**surgical intervention not indicated
What can occur as a result of auriculotemporal nerve injury in parotid surgeries?
Frey’s syndrome: auriculotemporal carries parasymp fibers to the parotid and symp fibers to the skin
Aberrant regerneration an cause gustatory sweating
What perfect of thyroid nodules dx as follicular neoplasms on FNA end up being malignant?
20%
What is the most common site of iatrogenic CSF leak during sinus sugery?
Lateral lamella of the cribriform plate
What mass of the CP angle will be isointense to brain on T1 and T2, strongly enhances with contrast, and has a broad base of dural enhancement?
Meningiomas
How do cholesteatomas appear on T1 vs T2?
Hypointense on T1
Hyperintense on T2
Do not enhance with contrast
How do cholesterol granulomas appear on T1 and T2?
Hyperintense on T1 and T2
Do not enhance with contrast
How do vestibular schwannomas appear on T1 and T2?
Isointense on T1 and T2 with foci of high density on T2
Strongly enhance with contrast but do NOT have broad based dural attachment
Where is nystagmus directed in patient with vestibular neuritis?
Fast phase away from the the affected side
What are risk factors for Hashimoto’s thyroiditis?
Female gender
Diabetes mellitus
Sjogren’s syndrome
HLA-DR3
Where does the right vs left recurrent laryngeal nerve branch off the vagus?
Right: T1-2, anterior to the right subclavian
Left: in the thorax
What is the clinical significance of recurrent laryngeal dysfunction in the setting of normal pharyngeal sensation?
Lesion must be distal to the pharyngeal branch of the vagus nerve
What gives rise to the visceral motor fibers of the vagus nerve (pharyngeal branches and superior and inferior laryngeal nerves)
Nucleus ambiguous
What contains the cell bodies of visceral sensory nerves that include cerviccal thoracic, and abdominal fibers, innervate the carotid and aortic bodies, and send branches to the epiglottis and taste buds
Nucleus tractus solitarius
What are the main functional secretory cells of the parathyroid glands?
What are the less numerous cells that stain more deeply and are rich in mitochondria
Chief cells
Oxyphil cells
**may also be intermediate cells
Is clindamycin bacteriocidal or bacteriostatic?
Bacteriostatic
What is the auditory pathway from the cochlea to the brain?
Cochlear nucleus
Acoustric stria to the
Superior olivary complex and inferior colliculus
Auditory cortex
Match the inferior colliculus and the superior colliculus to visual and auditory
Inferior: auditory
Superior: visual
What is a Pott’s Puffy tumor?
Non-neoplastic condition occuring as a result of prior frontal sinus trauma, acute/chronic frontal sinusitis, or previous sinus surgery
Leads to mucopyocele formation and subperiosteal abscess with underlying osteomyelitis
What is general tx of a Pott’s Puffy tumor?
Surgical drainage and IV abx for 6-8 weeks
What happens to the width and cross sectional area of the choana in congenital nasal pyriform aperture stenosis?
Width reduced
Cross sectional area unchanged
What does non-operative treatment of congenital nasal pyriform aperture stenosis include?
Topical nasal vasoconstrictors
Nasal tubes
What should you aggressively screen for when you identify a patient with laryngomalacia?
GERD: reported as high as 50-100% of laryngomalacia population
What should be done for a child who is noted to have bifid epiglottis?
MRI of the brain–high association between bifid epiglottis and hypothalmic dysfunction
What syndrome is associated with polydactyly, pituitary dysfunction, imperforate anus, and hamartoblastomas?
Pallister-Hall syndrome
What syndrome encompasses laryngotracheal cleft, hypertelorism, cleft palate, and hypospadias?
Opitz-Frias syndrome
What is the medical term for a small chin?
Microgenia
What is the definition of class I occlusion?
Mesiobuccal cusp of the maxillary front molar is directly in line with the buccal groove of the permanent mandibular first molar
What is the lateral border of the paraglottic space? Medial border? Posterior?
Lateral: thyroid cartilage and cricothyroid membrane
Medial: quadrangular membrane, ventricle, conus elasticus
Posterior: pyriform sinus mucosa
What is the equation for calculating dB based on two intensities?
x dB = 10log(I1/I2)
What increase in dB will double sound intensity?
3 dB
What approach to CPA tumor is best for a patient with good preoperative hearing and a small, intracanalicular tumor?
Middle fossa approach
**offers exposure to the IAC but not the CPA
What population should not have a middle fossa approach to a CPA tumor?
Geriatric population: 2/2 fragility of dura and the need for temporal lobe retraction
What CPA tumor approach provides superior exposure to the CPA while preserving hearing, but cannot offer good exposure to intracanalicular tumors?
Retrosigmoid approach
What two approaches to CPA tumors injure the otic capsule?
Transcochlear
Translabyrinthine
What approach to a CPA tumor requires cerebrellar retraction but offers good exposure of the CPA?
Suboccipital approach
What is the optimal time to dermabrade scars post-op?
6-8 weeks
In transplant patients or those with hematologic malignancies, what PMN count is linked with the onset of acute invasive fungal sinusitis and reduced survival?
1000 mm3
In transplant patients or those with hematologic malignancies, what PMN count is linked with the onset of acute invasive fungal sinusitis and reduced survival?
1000 mm3
Which of the ossicle is most commonly eroded by a cholesteatoma?
Incus
Malleus gets displaced with widening of Prussak’s space
What plane should scalp tissue expanders be placed in?
Subgaleal plane, above the periosteum
How long after placement of tissue expander placement can inflation begin?
2 weeks (needs sufficient time to heal)
What is a rule of thumb for the base width of a tissue expander for the scalp in relation to the width of the defect?
Expander should be about 2.5x the width of the defect
What is the Centor criteria for strep throat?
Fever
Tender lymphadenopathy
Exudative tonsillitis
Absence of cough
What is the sensitivity and specificity of the rapid strep test?
90% sensitive
95% specific
A Centor score of 4/4 equates with a __% chance of GABHS infection
60%
What is the overall incidence of rheumatic fever in pediatric GABHS pharyngitis patients?
0.3% (1-3% in the adult population)
What should be done during a stapedectomy with PORP placement if the incus is found to be dislocated?
Abort the procedure and complete in 4-6 mo when the incus is reattached to the malleus
What malignancy is a patient with sjogren’s syndrome at higher risk for?
Mucosa-associated lymphoid tissue lymphoma
SS-A and SS-B is elevated in what percent of pts with active Sjogren’s
50-70%
What is the most common salivary gland malignancy?
Mucoepidermoid carcinoma
Are males or females more likelyto get mucoepidermoid carcinoma?
Females
What types of cells are more prevalent in high grade mucoepidermoid carcinomas?
Higher proportion of epithelial cells, fewer mucoid cells
In what week of development does the extratemporal portion of the facial nerve begin development?
6th gestational week, all branches present at the end of the 8th week
The nervus intermedius contains preganglionic parasympathetic nerve fibers supplying innervation to what glands:
Lacrimal
Submandibular
Sublingual
Minor salivary glands
What is the diameter of the larybrinthine segment of the facial nerve?
0.7 mm
What is the name of the bony prominence which projects from the roof of the epitympanum, superior to the facial nerve as it enters the facial cavity?
Cog
What is the tullio phenomenon?
Vertigo and nystagmus in response to loud sounds
In what situations is the Tullio phenomenon seen?
Superior canal dehiscence
Syphilis
What is the most common location of synovial sarcoma in the head and neck?
Hypopharynx–arise from pluripotent mesenchymal cells
What are the two types of synovial sarcomas?
Monophasic form composed of spindle cells
Biphasic form composed of epithelial and spindle cells
What is the most common location of osteosarcoma in the head and neck?
Mandible and maxilla
What is the most common location of liposarcoma in the head and neck?
Neck
What is the most common location for chondrosarcomas?
Larynx
Also seen in the petrous temporal bone, clivus, maxilla, and mandible
What are the 4 parasympathetic ganglia in the head and neck?
- Otic
- Submandibular
- Pterygopalatine / sphenopalatine
- Ciliary
What is the small parasympathetic ganglion located just inferior to the foramen ovale what carries parasympathetic fibers for salivation of the parotid?
Otic ganglion
What ganglion is located near the posterior edge of the mylohyoid mucle just over the hyoglossus muscle
Submandibular ganglion
Preganglionic parasympathetic fibers within the chorda tympani never travel along with the lingual and synapse in the ____ ganglion before innervating the sublingual and submandibular glands
Submandibular ganglion
Preganglionic parasympathetic fibers carried in the greater superficial petrosal nerve synapse in what ganglion
Pterygopalatine/spehnopalatine
Post-ganglionic fibers that synapsed in the ___ ganglion innervate the sphincter pupillae and cause miosis
Ciliary
What medication can help prevent epistaxis in a patient with chronic kidney disease who is on coumadin
DDAVP: uremia can cause inactivation of platelets and desmopressin (intranasal or subcutanous), can also be used for Von Willebrand disease
What are the boundaries of the frontal recess?
Medial: middle turbinate
Lateral: lamina papyracea and uncinate
Anterior: posterior wall of the agger nasi
Posterior: anterior edge of the ethmoid bulla
Abnormality of what embryonic process leads to medial cleft lip?
Abnormal fusion of the medial nasal processes
What is the epithelium of the supraglottis?
Glottis?
Pseudostratified columnar
Stratified squamous
What is a type IV tympanoplasty
Absent or eroded suprastructure with the graft or TM overlying mobile stapes footplate
What is a type V tympanoplasty
Stapes footplate is fixed
Va: grafting over a fenestration created in the horizontal semicircular canal
Vb: stapedectomy **more common
What are the prognostic factors for papillary thyroid carcinoma according to the AMES criteria?
Age: >41 for men, >51 for women
Metastasis
Extrathyroidal invation
Size: >5cm
What type of branchial cleft cyst will drain into the pyriform sinus
Where will it travel with respect to the internal/external carotid, the hypoglossal and glossopharyngeal
Third branchial cleft cyst
Posterior to the internal carotid artery and between the hypoglossal and glossopharyngeal
What type of branchial cleft cyst will pass between the internal and external carotid arteries and superficial to the hypoglossal and glossopharyngeal?
Second branchial cleft cyst
Where will a first branchial cleft cyst terminate?
External auditory canal
What is the most common finding on laryngoscopy in the setting of laryngomalacia?
Inspiratory collapse of accessory arytenoid cartilages and mucosa into the glottis
**will also see posteriorly displaced epiglottis and shortened AE folds
What are indications for supraglottoplasty in a child with laryngomalacia
History of apneic events/ALTEs
Failure to thrive
Cyanosis
Cor pulmonale
What is the treatment for Stage II lyme?
Doxycycline 100 mg BID for 21 days
At what stage of Lyme disease is Bells palsy typically seen?
Stage II (disseminated disease), accompanied by migratory myalgias, generalized rash, fevers, and chills
What organism causes Lyme?
Borrelia burgdorferi
What is the best treatment for a T2b or T3 melanoma?
Wide local excision with 1-2 cm margins with sentinel lymph node biopsy
What is present on pathologic evaluation of a JNA?
Gross: sessile, lobulated, rubbery dark red to tan gray mass
Micro: Admixture of vascular tissue and fibrous stroma. Vessel walls have incomplete or absent smooth muscle
What arteries supply the trapezius?
Transverse cervical (descending branches)
Dorsal scapular
Occipital
What is the differential blood supply of the following flaps?
- Inferior trapezius flap
- Lateral island flap
- Superior trapezius flap
Dorsal scapular and descending branches of the transverse cervical
Superficial branches of the transverse cervical
Which of the trapezius flaps provides the longest pedicle?
Inferior trapezius flap
The parotid duct exits the parotid parenchyma, passes over the masseter, and turns medially to pierce the ***
Buccinator
Where does stenson’s duct empty into the oral cavity?
Second maxillary molar
What are the subsites of the supraglottis?
Aryepiglottic folds Arytenoids Suprahyoid epiglottis Infrahyoid epiglottis Arytenoids
What branchial pouches are the inferior and superior parathyroid glands derived from?
Inferior: 3rd
Superior: 4th
What structure do the inferior parathyroid glands migrate with caudally and medially during development?
Thymus
Where should you look for superior parathyroid glands if they are not in the expected location during an exploration?
Tracheoesophageal groove
Posterior mediastinum
Within the carotid cheath
Where should epi be injected during anaphylaxis?
Vastus lateralis
What is the dosing of epi for anaphylaxis in adults?
Adults: 0.3-0.5 mg of 1:1000
A lymph node that demonstrates __% or greater counters per minute compared with the hottest node ex vivo should be considered a sentinel node and be removed
10%
Most common location of involvement of otosclerosis?
Bone anterior to the oval window with a small cleft known as the fissula ante fenestrum
What is the risk of malignancy per the Bethesda system for a follicular neoplasm?
15-30%
What are features of the lower lateral cartilage in a cleft lip?
Normal size and width Shortened medial crus Elongated lateral crus Blunted dome Posteriorly, laterally, and inferiorly displaced alar base
Which strains of HPV do gardasil vs cervarix protect against?
Gardasil: 6, 11, 16, 18
Cervarix: 16, 18
Is gardasil or cervarix only indicated for women?
Gardasil
What embryological precursor forms the eustachian tube?
First branchial pouch
What is the MOA of avastin?
What can injection of avastin be used to control?
VEGF inhibitor
Respiratory papillomatosis
What is the autoimmune thyroiditis in which normal parenchyma is replaced by extensive fibrosis
Riedel’s thyroiditis
What does an UPSIT score less than 5 suggest?
Malingering
What scores on the UPSIT test coorespond to anosmia and hyposmia?
Anosmia: 5-18
Hyposmia: 19-33
**total score of 40
What is the most common complication following Sistrunk procedure?
Recurrence
Primary hyperparathyroidism is caused by one or more adenoma __% of the time and diffuse hyperplasia __% of the time?
75-80%
20%
In MEN 1, hypercalcemia is seen in __% of patients
In MEN 2a, hypercalcemia is seen in __% of patients
95%
5-20%
What artery is the main pedicle of a paramedian forehead flap?
Supratrochlear artery
What is the mechanism of action of mitomycin C?
Antitumor antibiotic causing cross linking of DNA
What drug binds dihydrofolate reductase and has a rate limiting step of mucositis, with an increased toxicity in patients with kidney failure given renal excretion
Methotrexate
Lund-Mackay system for scoring of chronic rhinosinusitis
0: no abnormalities
1: partial opacification
2: complete opacification
* *24 points available, 12 pre side
What is the effect of using antibiotic drops after tympanostomy tube placement?
Reduce post-tympanostomy tube otorrhea (most common complication following T tube insertion)
What is used to calculate the OSAHS score
BMI
Tonsillar size
Freidman tongue size
Which salivary gland has the highest percentage of malignant tumor formation? Middle? Lowest?
Minor salivary glands > submandibular gland > parotid gland
What is the most common malignant tumor of the partoid?
Mucoepidermoid carcinoma
What is the most common malignant tumor of the submandibular gland?
Adenoid cystic carcinoma
Increase in calcitonin is indicative of what kind of thyroid cancer?
Medullary thyroid carcinoma
With papillary thyroid carcinoma, are regional and distant metastases more common in children or adults?
Children, though prognosis is favorable
What is the University of Pittsburgh Staging System for temporal bone neoplasms?
T1: Tumor limited to the EAC without bonyerosion or evidence of soft tissue extension
T2: Tumor with limited EAC bony erosion or soft tissue involvement (less than 0.5cm)
T3: Tumor eroding the osseous EAC (full thickness) with limited (less than 0.5 cm) soft tissue involvement, or tumor involving middle ear or mastoid
T4: Tumor eroding the
What is the ideal position for the highest part of the brow in women?
Above the lateral limbus or lateral canthus
What is the ideal shape of a male brow?
No arching, sits at the supraorbital rim
What bacteria should you prophylactically treat for when you are using medicinal leeches
Aeromonas hydrophila: gram negative rod in leech gut, sensitive to 3rd generation cephalosporins, ciprofloxacin, aminoglycosides, sulfa drugs, and tetracycline
What bacterial infection is classically associated with Lemierre’s syndrome?
Fusobacterium necrophorum
What are the embryonic sources of the ossicles?
First arch: - malleus (minus the manubrium) - incus (minus the long process) Second arch: - manubrium of the malleus - long process of the incus - suprastructure of the stapes
**footplate arises from the otic capsule
What are two species that are often found in patient with allergic fungal sinusitis?
Curvularia
Bipolaris
Are children or adults more likely to present with unilateral allergic fungal sinusitis?
Children (70%)
What do the following precursors eventually form: 1st ethmoturbinal 2nd ethmoturbinal 3rd ethmoturbinal 4th and 5th ethmoturbinal
1st: agger nasi and uncinate
2nd: middle turbinate
3rd: superior turbinate
4th and 5th: supreme turbinate
In the porus acousticus, where is the facial nerve in relation to Bills bar and the transverse crest?
The facial nerve is located anterior and superior
What is produced by the chief cells in the stomach and is enzymatically active at an acidic pH, but has proteolytic activity at normal pH (ie pharynx and larynx)
Pepsin
What is the most common causative organism in cavernous sinus thrombosis?
Staph aureus
What is the most common inherited form of congenital facial palsy?
Congenital unilateral lower lip palsy–atrophy of the depressor anguli oris muscle
Between what two structures can deep lobe parotid tumors extend to the parapharyngeal space, creating a dumbbell appearance?
Mandible
Stylomandibular ligament
**through the stylomandibular membrane
Prestyloid tumors lie anterior to the carotid artery and usually arise from:
Poststyloid tumors lie posterior to the carotid artery and usually arise from:
Salivary
Neurogenic
What three studies are mandatory for zone 1 neck injuries (clavicles tot he cricoid)
CXR
CT angiography
Gastrograffin swallow study
What are the most common sites of cervical metastases in base of tongue cancer?
Zones II-IV
Cochlear afferents first synapse in what nuclei?
Dorsal and ventral cochlear nuclei
What is Donaldson’s line?
Hypothetical line that runs parallel to the horizontal semicircular canal and biscets the dome of the posterior semicircular canal
Marks the superior boundary of the endolymphatic sac
What are the boundaries of the internal nasal valve?
Nasal septum
Caudal border of the ULC
Head of the inferior turbrinate
What cartilage is used for an autograft spreader technique to increase the patency of the the internal nasal valve during functional septorhinoplasty
ULC: medially infolded and suture stabilization, obviates need for free cartilage graft
What is a sensitive lab test for Wegners?
C-ANCA
What is the footplate of the stapes derived from?
Otic mesenchyme
What ossicular structures does the first branchial arch give rise to?
Head and neck of the malleus
Body and short process of the incus
What ossicular structures does the second branchial arch give rise to?
Manubrium of the malleus
Long process of the incus
Stapes superstructure
What is the most muscle to reconstruct in cleft palate surgery?
Levator veli palatine: elevates the palate and is responsible for velopharyngeal closure during the swallow mechanism
What is Chandler’s staging system for JNA?
Stage 1: confined to the nasopharynx
Stage 2: extends to the nasal cavity or sphenoid
Stage 3: involves the maxillary sinus, ethmoid sinus, infratemporal fossa, orbit, cheeck, cavernous sinus
Stage 4: intracranial extension
What growth arises from the lateral nasal wall in the region overlying the sphenopalatine canal?
JNA
What is the Holman-Miller sign?
Pathognomonic radiologic sign of JNA where growth of JNA pushes the posterior maxillary wall anteriorly
What is the most common site of metastasis of ACC?
Lung: indolent but relentless course, seldom metastasizes to regional lymph nodes
What are the T1 and T2 imaging findings of cholesterol granuloma?
T1: Hyperintense
T2: Hyperintense
What is the maximum size upper eyelid defect that can be closed primarily?
25% or less
What is the only peeling agent that requires neutralization to end its action (5% sodium bicarbonate)
Glycolic acid
What is Ramsay-Hunt syndrome?
Varicella zoster visus infection leading to vesicular eruptiong in the conchal bowl and facial palsy (House-Brackmann IV-VI in 50% of patients)
What is standard treatment for Ramsay-Hunt syndrome?
Valacyclovir for 14 days OR
Famciclovir of 10 days with steroids
What is Gorlin’s syndrome?
AD disorder associated with falx calcifications, multiple cutaneous BCC, odontogenic keratocysts, bifid ribs, scoliosis, and frontal bossing
What is PFAPA syndrome?
Periodic fever, aphtous stomatitis, pharyngitis and adenitis: periodic fevers >39 lasting 3-7 days recurring every 21-42 days. Resolution of sx s/p tonsillectomy if abx fail
What is the most common cause of temporary diplopia s/p blepharoplasty?
Permanent?
Post-operative edema
Injury to the inferior oblique
What is the area of weakness that leads to a Zenker’s diverticulum?
Killian’s triangle: limited superiorly by the inferior constrictor and inferiorly by the cricopharyngeus
What type of thyroid carcinoma is the BRAF V600E mutation associated with?
Papillary thyroid carcinoma
What is the most common malignancy to arise within the nasal cavity and paranasal sinuses in children?
Rhabdomyosarcoma
What is the grading system for the slope of the skull base, and how many types are there?
Keros type I: 1-3 mm
Keros type II: 4-7 mm
Keros type III: 8-16 mm
**measured from the cribriform plate to the fovea ethmoidalis of the frontal bone
What is the criteria for drainage of a PTA in a child?
Abscess >2 cm
Respiratory distress
Failure of IV abx
What are the cooresponding structures to hillocks of His 1-6
1: Tragus
2: Helical crux
3: Helix
4: Antihelix
5: Antitragus
6: Lobule
What is the most common cause of pediatric facial fractures?
MVCs
What condition is often associated with congenital lower lip paralysis (CULLP)?
Cardiac defects (Cayler craniofacial syndrome when combined)
What is the source of the majority of hyperparathyroidism?
Single parathyroid adenoma (85%)
What % of patients with Downs have atlantoaxial instability (greater than 4mm distance between the dens and the anterior arch of the atlas)?
10-20%
What is the name of a painful thyroid following a URI? What is the treatment
DeQuervain’s subacute thyroiditis
NSAIDs and corticosteroids
The eustachian tube, middle ear, and mastoid cavity are all derived from what embryologic structure?
First pharyngeal pouch
What is appropriate therapy for necrotizing fascititis?
Ceftriaxone 2 gm IV q8h
Clindamycin 600 mg IV q8h
Metronidazole 500 mg IV q6h
What mutation underlies Alport syndrome, x-linked form of SNHL associated with progressive glomerulonephritis?
COL4A5, product participates in collagen IV synthesis (present in the basement membrane and the inner ear)
Which of the CPA approaches carry the highest risk of facial nerve injury?
Middle cranial fossa
What are the primary adductors of the vocal folds?
Lateral crico-arytenoid
What is the difference between a subtotal and total temporal bone resection?
Subtotal: removal of the otic capsule and facial nerve but spares the petrous apex and carotid artery
**those are removed in a total temporal bone resection
What is the term for decrease in speech recognition performance at higher signal intensity?
Rollover
**assoc with RCP
What is the term for poor speech recognition out of proportion to that which would be predicted by PTA results?
Phonemic regression
**assoc with RCP
What is the term for a test in which a tone is presented continuously to an ear with a hearing loss until it becomes inaudible?
Tone decay
**excessive tone decay associated with RCP
What is the term for increases in perceived loudness of a sound in an ear with SNHL?
Recruitment
**assoc with RCP
What is Lugol’s solution?
Potassium iodine and elemental iodide in water
Which direction does the columella and nasal septum deviate in a patient with unilateral cleft lip and palate?
Towards the noncleft side
What CD markers are found on NK cells?
CD16
CD56
What CD markers are found on B cells?
CD 19
CD 20
CD 22
ORN rarely occurs in pts who have been exposed to less than __ Gy
60
Though Crouzon syndrome presents similarly to Apert and Pfeiffer syndromes wih craniosynstosis, midfaial hypoplasia, and ocular proptosis with a parrot-beak nose, what additional findings are seen in Apert and Pfiffer?
Apert: syndactyly
Pffiefer: broad thumbs and toes
What are characteristics associated with central vertigo?
Doesn’t extinguish with repeated stimulation
Less severe
Nystagmus that doesn’t improve with fixation and multidirectional
What are the two key types of proteins expressed by HPV?
E proteins (1-7): early L proteins (1-2): late
What is the major capsid protein in Gardasil and Cervarix?
L1: structural protein that encapsulates the viral particle
What are the roles of HPV proteins E6 and E7 (early proteins)
E6: inhibits p53
E7: inhibits pRb
The levator palpebrae superioris muscle is suspended by what structure?
Whitnall ligament: extends from the fascia of the lacrimal gland laterally to the trochlea attachment medially
What is Lockwood ligament?
Thickening of Tenon’s capsule, forms a hammoch stretching below the eyeball between the medial and lateral canthal tendons, encloses the inferior rectus and inferior oblique muscles
What is the involuntary smooth muscle lid retractor that receives sympathetic innervation located beneath the levator aponeurosis
Muller muscle
What is the tx for benzo overdose?
Flumazenil: initially 0.2 mg IV, increased by to 3 mg/hr if there is no response
What is the difference between N2a, b, and c laryngeal cancers?
a: single ipsilateral LN 3-6 cm
b: multiple ipsilateral LN <6cm
c: bilateral or contralateral LN <6cm
What two teeth does a cleft lip form between?
Lateral incisors and canines
What is the most important factor for the outcome of atresia repair?
Stapes: only element that gets 2 points on the *** scale, implies inner ear pneumatization
What nerve provides cutaneous innervation for the radial forearm free flap?
Lateral antebrachial cutaneous nerve
What chemokine is secreted by active T helper cells?
IL-2
What is the maximum dose of lidocaine that can be safely given with and without epi? (in mg/kg)
WITHOUT 4mg/kg
WITH 7mg/kg
How many mg/ml does 1% lidocaine have?
10 mg lidocaine/ml
**4% will have 40 mg/ml
What is the best type of audiologic testing for children from 6 to 30 mo
Visual reinforcement audiometry
Is nystagmus enhanced or supressed with ocular fixation in central vertigo?
Enhanced
What are the limbs of the nasal tripod?
Conjoined medial crura and bilateral lateral crura
What subtypes of HPV cause RRP?
6 and 11
How high should you stay above the orbital rim to avoid ptosis with botox injections?
1 cm
If ptosis is produced w botox injections, how should it be treated and was it the MOA?
Apraclonidine gtts
Alpha 2 agonist which causes Muller muscle contraction
What dose of epi should be given for anaphylaxis?
0.01 mg/kg (max 0.5 mg) every 5-15 min if anaphylaxis persists
Which incision allows for a retrograde approach in rhinoplasty?
Intercartilaginous: followed by dissection of the vestibular lining retrogrady over the underside of the lateral crus of the lower lateral cartilage
Which two incisions allow for an open approach to rhinoplasty?
Marginal
Transcolumellar
What is the best tx option initially for presbylaryngis
Voice therapy
What differentiates class IV and V Norwood hair loss classes?
IV: Frontal and vertex loss, but still a band of hair separating two areas
V: Loss of separation between frontal and vertex areas of hair loss
What is the 1st ethmoturbinal the precursor for?
Agger nasi
Uncinate