board review practice exam Flashcards
virulence factor found only in gram positive organisms
Teichoic acids
major virulence factor of streptococcus pneumoniae
Capsule - antiphagocytic
what organism has the following characteristics causes dry hacking cough, causes atypical walking pneumonia, has a high titer of cold agglutinins and lacks a cell wall
myscoplasma pneumoniae
name the organism: catalase +; coagulase -; mannitol salt -; novobiocin resistant
staphylococcus saprophyticus
Ability to take up naked DNA from the environment known as what in bacterial genetics?
Transformation
what process involves an F+ plasmid and a sex pilus?
Conjugation
What is the process whereby a segment of DNA can jump from one location to another
Transposition
This process in bacterial genetics involves viruses
Transduction
Name the organism: sorbitol negative, lactose fermenting, gram negative rods, causes bloody diarrhea
EHEC
What is a complication of EHEC?
Hemolytic-Uremic Syndrome (triad of anemia, thrombocytopenia, acute renal failure)
Name the organism: gram negative, lactose negative rod; causes ROSE SPOTS on abdomen, fever, headache and diarrhea; can remain in gallbladder and cause carrier state
salmonella typhi
Name the organism: gram negative, lactose negative rod; does not cause typhoid fever
salmonella enterica biovar typhimurium
Name the organism: gram negative rod; causes high fever, swelling in armpits and groin area
yersinia pestis - bubonic plague
How is yersinia pestis transmitted?
Fleas
Salmonella or Shigella? have flagella, disseminate hematogenously, produce hydrogen sulfide, can cause bloody diarrhea, does not ferment lactose , many animal reservoirs
Salmonella
Salmonella or Shigella? no flagella, cell to cell transmission, does not produce hydrogen sulfide, often causes blood diarrhea, does not ferment lactose, only reservoirs are humans and primates
Shigella
What is the MOA of the shigella toxin?
inhibition of protein synthesis
What type of organism is diphyllobothrium latum?
Cestode (tapeworms)
How is diphyllobothrium latum transmitted?
ingestion of larvae from raw freshwater fish
How is diphylllobothrium latum treated?
praziquantel
What condition does diphyllobothrium latum cause?
vitamin B12 deficiency - tapeworm competes for B12 in intestine causing anemia
Name the organism: pigs are reservoir, causes watery diarrhea with blood and pus
Balantidium coli
Beavers and muskrats are reservoirs for this protozoa
Giardia lamblia
Describe disease caused by Giardia lamblia
bloating, flatulence, foul-smelling, fatty diarrhea
Name the organism: severe diarrhea in AIDS patients, watery diarrhea in immunecompetent, cysts seen on acid fast stain
cryptosporidium
Which organism as the following clinical disease description? mimics giardiasis with malabsorption syndrome
Cystoisospora belli
A trematode (fluke) with a terminal spine
Schistosome haematobium
A trematode (fluke) with a lateral spine
Schistosome mansoni
A trematode (fluke) with a non-distinct spine
Schistosome japonicum
Neonatal manifestations of toxoplasma gondii
chorioretinitis, hydrocephalus, intracranial calcifications
Neonatal manifestations of rubella
pulmonary artery hypoplasia, CATARACTS, deafness, blueberry muffin rash
Neonatal manifestations of CMV
hearing loss, seizures, petechial rash, blueberry muffin rash, microcephaly, low birth weight
Neonatal manifestations of HSV-2
encephalitis, herpetic lesions
Neonatal manifestations of syphilis
stillbirth, hydrops fetalis, notched teeth, sadles nose, short maxilla, saber shins, CN VIII deafness
Name the virus: heterophile +, atypical lymphocytes, a herpes virus
EBV
Does enterovirus cause GI symptoms?
NO
Name the virus: flu like symptoms and flaccid paralysis with no sensory less
poliovirus
how is poliovirus transmitted?
fecal-oral
Site of latency for HSV-1
trigeminal ganglia
Site of latency for VZV
dorsal root ganglia
Site of latency for HSV-2
sacral ganglia
Virus that causes black vomit
Yellow fever virus
What virus causes temporal lob encephalitis
HSV-1
T/F a complication of adenovirus can also be hematuria
true
The Ixodes tick transmitts what two conditions?
Lyme Disease and Babesia (hence possible coinfection)
Blood smear shows a maltese cross, what does this indicate?
Babesia
Name the virus: single stranded RNA virus, most common cause of myocarditis
Coxsackie B virus
Warts on a 10 year olds hands points to what virus?
HPV
What type of virus is HPV?
non-enveloped DNA virus
What does the presence of HBeAg indicate?
chronic infection
What is common in second stage lyme disease?
Bell Palsy
Name the bug: gram negative rods with bipolar staining; causes fever, malaise, dyspnea, chest pain
Yesinia pestis
Name the bug: weakness, backache, arthralgias, fever that is worse at night, profuse sweating
Brucella abortus
Name the bug: fever, malaise, vesicular rash in the oral mucosa, vesicles are all the same age
Small pox virus
Name the mold - septate hyphi that branch at 45 degree angles, appearance of fungus ball on chest xray
Aspergillus fumigatus
Name the fungus - found in states east of the Mississippi Rive and centeral america, broad base budding
Blastomycosis
Name the mold - seen mostly in ketoacidotic diabetics, black necrotic eschar can form
Mucor and Rhizopus
What does Mucor look like on histological image?
nonseptate hyphae branching at wide angles
Name the fungus - found in southwestern US, California, causes pneumonia and meningitis, SPHERULES filled with endospores
Coccidioidomycosis
Name the organism - dimorphic yeast, pseudohyphae and budding yeasts; causes oral and esophageal thrush in immune compromised
Candida albicans
Name the organism - encapsulated, found in pigeon droppings and soil, stains with india ink
Cryptosporidium neoformans
Name the organism - symptoms include fever, night sweats, weightloss and hemoptysis, surface glycolipids inhibit phagolysosome fusion
Mycoplasma tuberculosis
ring enhancing lesions in the brain suggest what?
Toxoplasma gondii
Describe the measles virus
RNA, negative stranded, enveloped
Trypanosoma cruzi which causes Chagas disease is transmitted by what?
Reduviid bug
Name the bug - causes malaise, chills, sore throat, dry cough, intersitial pneumonia; does not gram stain, sputum reveals PMNs but no organisms
Chlamydophila pneumoniae
those working at the aquarium and dealing with fish tanks are at risk for what?
mycobacterium marinum
Break bone fever is transmitted by?
(Dengue fever; Flavivirus) by Aedes mosquito
Where in the body is bacteroides fragilis part of the normal flora?
Colon
This organism is part of the normal flora of the colon and is gram negative and an obligate anaerobe
Bacteroides fragilis
T/F chlamydia trachomatis causes reactive arthritis
T
symptoms of pseudomembranous pharyngitis (grayish white membrane) with lymphadenopathy, myocarditis and arrhythmias indicate what organism?
Corynebacterium diphtheriae
post streptococcal glomerulonephritis is considered what type of hypersensitivity?
Type III
Campylobacter jejuni is a common antecedent to what?
Buillain-Barre syndrome and reactive arthritis
Name the organism - blood and pus in stool, fecal oral transmission, oxidase positive, GROWS AT 42 DEGREES
Campylobacter jejuni
exposure to aborted fetus from a sheep is associated with which organism?
Brucella meletensis
Parvovirus B19 is what type of virus?
single stranded DNA virus (the only singled stranded DNA virus)
Name the organism - motility causes swarming on agar; produces urease; ASSOCIATED WITH STRUVITE STONES
Proteus mirabilis
name the parasite - associated with bears, myalgia, persistent low grade fever
Trichinella spiralis
Name the parasite - severe edema of lower legs
Wucheria bancrofti
Name the parasite- associated with Africa, diminished visual acuity
Onchocerca volvulus
What parasite also affects the eye but does not cause blindness like Onchocerca volvulus
Loa Loa
Vector for African sleeping sickness (Trypanosoma brucei)
Tsetse fly
Vector for Chagas Disease (Trypansoma cruzi)
Reduviid bug
Vector for Elephantiasis (Wuchereria bancrofti)
Female Mosquito
Vector for River blindness (onchocerca volvulus)
Black fly
Vector for Malaria (Plasmodium)
Anopheles Mosquito
Vector for Leishmaniasis
sand fly