BNF-riffat's revision Flashcards
memorising
Occasional treatment for travellers diarhorea
Ciprofloxacin
which antidiarhoea drug should be avoided in bloody diarrhoea and in febrile patients
loperamide
treatment of fistulating crohns
ciprofloxacin OR metronidazole for 1/12 but not more than 3/12 due to comcerns with peripheral neuropathy
in deficient states of thiopurine methyltransferase (TPMT) do not give what medicines?
mercaptopurine azathioprine
side effects of sulfasalazine
stains contact lens
insomnia
altered taste
stomatitis
side effects of aminosalicylates
lupus erythematous syndrome
blood dyscrasias
monitor for blood dyscrasias (FBP)
renal funx before treatment and every 3 months
antibiotics causing visual problems
linezolid-optic nephropathy quinolones- retinal detachment ethambutol- ocular toxicity rifampicin- colors lens and tears red rifabutin- uveitis macrolide- eye discomfort
two things to look out for in linezolid treatment
optic nephrpathy
blood disorders monitor FBC in treatments exceeding 10-14 days. weekly monitoring
important warnings with ciprofloxacin
- tendon damage (also reported with prednisolone!!)
- reduces threshhold of convulsion, induces convulsions in those taking NSAIDs
- caution with epilepsy and theophylline
- can prolong QT interval
antibiotics that can cause QT prolongation
- quionolones
2. macrolides
If vancomycin infused too rapidly
Upper body flushing- RED MAN SYNDROME
also causes:
hypotension
wheezing pruitus
muscle spasm/ pain in the back
Myasthenia Gravis
CI with aminoglycosides
caution: tetracyclines and macrolides
do not offer to people under 18
quinolones- tendon damage
antibiotics that give false positive sugar test
cephalexin, nitrofurantoin
which skin condition will terbinafine exacerbate
psoriasis
